ID A0A2K6L3A9_RHIBE Unreviewed; 666 AA.
AC A0A2K6L3A9;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Zinc finger protein 333 {ECO:0000313|Ensembl:ENSRBIP00000018008.1};
GN Name=ZNF333 {ECO:0000313|Ensembl:ENSRBIP00000018008.1};
OS Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Rhinopithecus.
OX NCBI_TaxID=61621 {ECO:0000313|Ensembl:ENSRBIP00000018008.1, ECO:0000313|Proteomes:UP000233180};
RN [1] {ECO:0000313|Ensembl:ENSRBIP00000018008.1, ECO:0000313|Proteomes:UP000233180}
RP NUCLEOTIDE SEQUENCE.
RA Wu, C.-I. and Zhang, Y.;
RT "Genome of Rhinopithecus bieti.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSRBIP00000018008.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC family. {ECO:0000256|ARBA:ARBA00006991}.
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DR AlphaFoldDB; A0A2K6L3A9; -.
DR Ensembl; ENSRBIT00000041867.1; ENSRBIP00000018008.1; ENSRBIG00000033000.1.
DR GeneTree; ENSGT00940000163161; -.
DR Proteomes; UP000233180; Unplaced.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd07765; KRAB_A-box; 2.
DR Gene3D; 6.10.140.140; -; 2.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 11.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR036051; KRAB_dom_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR47772:SF4; REDUCED EXPRESSION 2-RELATED; 1.
DR PANTHER; PTHR47772; ZINC FINGER PROTEIN 200; 1.
DR Pfam; PF01352; KRAB; 2.
DR Pfam; PF00096; zf-C2H2; 8.
DR Pfam; PF13465; zf-H2C2_2; 1.
DR SMART; SM00349; KRAB; 2.
DR SMART; SM00614; ZnF_BED; 2.
DR SMART; SM00355; ZnF_C2H2; 10.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 7.
DR SUPFAM; SSF109640; KRAB domain (Kruppel-associated box); 2.
DR PROSITE; PS50805; KRAB; 2.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 10.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 10.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000233180};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 5..75
FT /note="KRAB"
FT /evidence="ECO:0000259|PROSITE:PS50805"
FT DOMAIN 204..275
FT /note="KRAB"
FT /evidence="ECO:0000259|PROSITE:PS50805"
FT DOMAIN 367..394
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 395..422
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 423..450
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 451..478
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 479..506
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 507..534
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 535..562
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 563..590
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 591..618
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 619..646
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 43..62
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 666 AA; 75427 MW; 6B593BC978280E65 CRC64;
MPESVTLEDV AVEFIQEWAL LGSARRSLCR YGMLDQCRTL TSRGTPPCKP SRVSQLGPRA
EPRATERGIL HATGIAWESQ LKPKELPSMQ ALLEEASSRD MQMGPGLFLR MQLVPSIEAK
ETPLTQEDQP ALQEPPWSPG CTGLKAAVQI QRVLIPVPTL GHPDPWVAED SAVPARDPAW
LQEDRVEEEA MAPGLPTARS QEPVTFADVA VVFTPEEWVF LDSTQRSLYR DVMLENYRNL
ASVADQLCKP TALSYLEQRG EQWTTDRGIL SDTCAEPQLQ PQEAIPSQDP FTEILSIDVK
GEQPQPGEKL YKYNELEKPF NSIEPLFQYQ KIHAGEVSYE CQESRNSFFQ STHLIVPEKI
RSGDKTYACN KCEKSFRYSS DLIRHEKTHT AEKCFDCQEC GQAFKYSSNL RRHMRTHTGE
KPFECSQCGK TFTRNFNLIL HQRNHTGEKP YECKDCGKAF NQPSSLRSHV RTHTGEKPFE
CSQCGKAFRE HSSLKTHLRT HTREKPYECN QCGKPFRTST HLNVHKRIHT GEKLYECGTC
GQVLSRLSTL KSHMRTHTGE KPYVCQECGR AFSEPSSLRK HARTHSGKKP YACQECGRAF
GQSSHLIVHV RTHSAGRPYQ CNQCEKAFRH SSSLTVHKRT HMGRENIRNG SLPLAMSHPY
CGPLAN
//
