ID A0A2K6L6J2_RHIBE Unreviewed; 883 AA.
AC A0A2K6L6J2;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Sorting nexin 13 {ECO:0000313|Ensembl:ENSRBIP00000019155.1};
GN Name=SNX13 {ECO:0000313|Ensembl:ENSRBIP00000019155.1};
OS Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Rhinopithecus.
OX NCBI_TaxID=61621 {ECO:0000313|Ensembl:ENSRBIP00000019155.1, ECO:0000313|Proteomes:UP000233180};
RN [1] {ECO:0000313|Ensembl:ENSRBIP00000019155.1, ECO:0000313|Proteomes:UP000233180}
RP NUCLEOTIDE SEQUENCE.
RA Wu, C.-I. and Zhang, Y.;
RT "Genome of Rhinopithecus bieti.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSRBIP00000019155.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the sorting nexin family.
CC {ECO:0000256|ARBA:ARBA00010883}.
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DR AlphaFoldDB; A0A2K6L6J2; -.
DR Ensembl; ENSRBIT00000043024.1; ENSRBIP00000019155.1; ENSRBIG00000033559.1.
DR GeneTree; ENSGT00950000182856; -.
DR Proteomes; UP000233180; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0043226; C:organelle; IEA:UniProt.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR CDD; cd06873; PX_SNX13; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR Gene3D; 1.10.167.10; Regulator of G-protein Signalling 4, domain 2; 1.
DR InterPro; IPR003114; Phox_assoc.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR016137; RGS.
DR InterPro; IPR036305; RGS_sf.
DR InterPro; IPR044926; RGS_subdomain_2.
DR InterPro; IPR037437; SNX13_PX.
DR InterPro; IPR013937; Sorting_nexin_C.
DR PANTHER; PTHR22775; SORTING NEXIN; 1.
DR PANTHER; PTHR22775:SF3; SORTING NEXIN-13; 1.
DR Pfam; PF08628; Nexin_C; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF02194; PXA; 1.
DR Pfam; PF00615; RGS; 1.
DR SMART; SM00312; PX; 1.
DR SMART; SM00313; PXA; 1.
DR SMART; SM00315; RGS; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR SUPFAM; SSF48097; Regulator of G-protein signaling, RGS; 1.
DR PROSITE; PS50195; PX; 1.
DR PROSITE; PS51207; PXA; 1.
DR PROSITE; PS50132; RGS; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000233180};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..24
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 30..51
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 97..284
FT /note="PXA"
FT /evidence="ECO:0000259|PROSITE:PS51207"
FT DOMAIN 326..433
FT /note="RGS"
FT /evidence="ECO:0000259|PROSITE:PS50132"
FT DOMAIN 485..606
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
SQ SEQUENCE 883 AA; 102841 MW; D89CA25EC57B23D5 CRC64;
MMPPTSLSIW GWGSLGIVLF LITFGPFVIF YLTFYILCFV GGGLVVTLLF GKTNSEKYLE
QCEHSFLPPS STGVPKCLEE MKREARTIKI DRRLTGANII DEPLQQVIQF SLRDYVQYWY
YTLSDDESFL LEIRQTLQNA LIQFATRSKE IDWQPYFTTR IVDDFGTHLR VFRKAQQKIT
EKDDQVKGTA EDLVDTFFEV EVEMEKEVCR DLVCTSPKDE EGFLRDLCEV LLYLLLPPGD
FQNKIMRYFV REILARGILL PLINQLSDPD YINQYVIWMI RDSNCNYEAF MNIIKLSDNI
GELEAVRDKA AEELQYLRSL DTAGDDYMQQ TGGQAHLFFW MTVEGYRVTA QQQLEVLLSR
QRDGKHQTNQ TKGLLRAAAV GIYEQYLSEK ASPRVTVDDY LVAKLADTLN HEDPTPEIFD
DIQRKVYELM LRDERFYPSF RQNALYVRML AELDMLKDPS FRGSDDGDGG MSLDDLSNVS
SDDSVQLHAY ISDTGVCNDH GKTYALYAIT VHRRNLNSEE MWKTYRRYSD FHDFHMRITE
QFESLSSILK LPGKKTFNNM DRDFLEKRKK DLNAYLQLLL APEMMKASPA LAHYVYDFLE
NKAYSKGKGD FARKMDTFVN PLRNSMRNVS NAVKSLPDSL AEGMTKMSDN MGKMSERLGQ
DIKQSFFKVP PLIPKTDSDP EHRRVSAQLD DNVDDNIPLR VMLLLMDEVF DLKERNQWLR
RNIKNLLQQL IRATYGDTIN RKIVDHVDWM TSPEQVADSV KRFRDAFWPN GILAETIPCR
DKSIRMRTRV AGKTKLLAIM PDELKHIIGA ETTRKGILRV FEMFQHNQLN RRMVYVFLEG
FLETLFPQYK FRELFNKLHS RSKQMQKYKQ KLQTTQAPSL QKR
//
