ID   A0A2K6L9D8_RHIBE        Unreviewed;       506 AA.
AC   A0A2K6L9D8;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Ubiquitin like modifier activating enzyme 1 {ECO:0000313|Ensembl:ENSRBIP00000020139.1};
GN   Name=UBA1 {ECO:0000313|Ensembl:ENSRBIP00000020139.1};
OS   Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Rhinopithecus.
OX   NCBI_TaxID=61621 {ECO:0000313|Ensembl:ENSRBIP00000020139.1, ECO:0000313|Proteomes:UP000233180};
RN   [1] {ECO:0000313|Ensembl:ENSRBIP00000020139.1, ECO:0000313|Proteomes:UP000233180}
RP   NUCLEOTIDE SEQUENCE.
RA   Wu, C.-I. and Zhang, Y.;
RT   "Genome of Rhinopithecus bieti.";
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSRBIP00000020139.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- PATHWAY: Protein modification; protein ubiquitination.
CC       {ECO:0000256|ARBA:ARBA00004906}.
CC   -!- SIMILARITY: Belongs to the ubiquitin-activating E1 family.
CC       {ECO:0000256|ARBA:ARBA00005673}.
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DR   AlphaFoldDB; A0A2K6L9D8; -.
DR   Ensembl; ENSRBIT00000044017.1; ENSRBIP00000020139.1; ENSRBIG00000034047.1.
DR   GeneTree; ENSGT00940000158975; -.
DR   UniPathway; UPA00143; -.
DR   Proteomes; UP000233180; Unplaced.
DR   GO; GO:0008641; F:ubiquitin-like modifier activating enzyme activity; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   Gene3D; 1.10.10.2660; Ubiquitin-activating enzyme E1, SCCH domain; 1.
DR   Gene3D; 3.10.290.60; Ubiquitin-activating enzyme E1, UFD domain; 1.
DR   InterPro; IPR045886; ThiF/MoeB/HesA.
DR   InterPro; IPR018965; Ub-activating_enz_E1_C.
DR   InterPro; IPR038252; UBA_E1_C_sf.
DR   InterPro; IPR019572; UBA_E1_SCCH.
DR   InterPro; IPR042063; Ubi_acti_E1_SCCH.
DR   InterPro; IPR035985; Ubiquitin-activating_enz.
DR   PANTHER; PTHR10953; UBIQUITIN-ACTIVATING ENZYME E1; 1.
DR   PANTHER; PTHR10953:SF155; UBIQUITIN-LIKE MODIFIER-ACTIVATING ENZYME 1; 1.
DR   Pfam; PF09358; E1_UFD; 1.
DR   Pfam; PF10585; UBA_E1_SCCH; 1.
DR   PRINTS; PR02045; F138DOMAIN.
DR   SMART; SM00985; UBA_e1_C; 1.
DR   SUPFAM; SSF69572; Activating enzymes of the ubiquitin-like proteins; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000233180}.
FT   DOMAIN          370..501
FT                   /note="Ubiquitin-activating enzyme E1 C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00985"
SQ   SEQUENCE   506 AA;  56756 MW;  EA2E8BF2B0A92898 CRC64;
     MGFHHVGQAG LEPLTSGDPP TLASQSAGIT GVSYCAWPGF SIEVGKWGRL GSFPTSRVAV
     SLVLGLFTDG PSNNACGNPF CQLWPHVICL LCLQWARDEF EGLFKQPAEN VNQYLTDPKF
     VERTLRLAGT QPLEVLEAVQ RSLVLQRPQT WADCVTWACH HWHTQYSNNI RQLLHNFPPD
     QLTSSGAPFW SGPKRCPHPL TFDVNNPLHL DYVMAAANLF AQTYGLTGSQ DRAAVATLLQ
     SVQVPEFTPK SGVKIHVSDQ ELQSANASVD DSRLEELKAT LPSPDRLPGF KMYPIDFEKD
     DDSNFHMDFI VAASNLRAEN YDIPPADRHK SKLIAGKIIP AIATTTAAVV GLVCLELYKV
     VQGHRQLDSY KNGFLNLALP FFGFSEPLAA PRHQYYNQEW TLWDRFEVQG LQPNGDEMTL
     KQFLDYFKTE HKLEITMLSQ GVSMLYSFFM PAAKLKERLD QPMTEIVSRV SKRKLGRHVR
     ALVLELCCND ESGEDVEVPY VRYTIR
//