ID   A0A2K6LG66_RHIBE        Unreviewed;       469 AA.
AC   A0A2K6LG66;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   SubName: Full=Keratin 14 {ECO:0000313|Ensembl:ENSRBIP00000022530.1};
GN   Name=KRT14 {ECO:0000313|Ensembl:ENSRBIP00000022530.1};
OS   Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Rhinopithecus.
OX   NCBI_TaxID=61621 {ECO:0000313|Ensembl:ENSRBIP00000022530.1, ECO:0000313|Proteomes:UP000233180};
RN   [1] {ECO:0000313|Ensembl:ENSRBIP00000022530.1, ECO:0000313|Proteomes:UP000233180}
RP   NUCLEOTIDE SEQUENCE.
RA   Wu, C.-I. and Zhang, Y.;
RT   "Genome of Rhinopithecus bieti.";
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSRBIP00000022530.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the intermediate filament family.
CC       {ECO:0000256|RuleBase:RU000685}.
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DR   RefSeq; XP_017735631.1; XM_017880142.1.
DR   AlphaFoldDB; A0A2K6LG66; -.
DR   STRING; 61621.ENSRBIP00000022530; -.
DR   Ensembl; ENSRBIT00000046421.1; ENSRBIP00000022530.1; ENSRBIG00000035212.1.
DR   GeneID; 108534672; -.
DR   KEGG; rbb:108534672; -.
DR   GeneTree; ENSGT00940000154602; -.
DR   OMA; TLNKEMA; -.
DR   OrthoDB; 4640531at2759; -.
DR   Proteomes; UP000233180; Unplaced.
DR   GO; GO:0045178; C:basal part of cell; IEA:Ensembl.
DR   GO; GO:0001533; C:cornified envelope; IEA:Ensembl.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0045095; C:keratin filament; IEA:Ensembl.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:1990254; F:keratin filament binding; IEA:Ensembl.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0042633; P:hair cycle; IEA:Ensembl.
DR   GO; GO:0045110; P:intermediate filament bundle assembly; IEA:Ensembl.
DR   GO; GO:0030216; P:keratinocyte differentiation; IEA:Ensembl.
DR   GO; GO:0048863; P:stem cell differentiation; IEA:Ensembl.
DR   Gene3D; 1.20.5.170; -; 1.
DR   Gene3D; 1.20.5.500; Single helix bin; 1.
DR   Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR   InterPro; IPR018039; IF_conserved.
DR   InterPro; IPR039008; IF_rod_dom.
DR   InterPro; IPR002957; Keratin_I.
DR   PANTHER; PTHR23239; INTERMEDIATE FILAMENT; 1.
DR   PANTHER; PTHR23239:SF368; KERATIN, TYPE I CYTOSKELETAL 14; 1.
DR   Pfam; PF00038; Filament; 1.
DR   PRINTS; PR01248; TYPE1KERATIN.
DR   SMART; SM01391; Filament; 1.
DR   SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 2.
DR   SUPFAM; SSF46579; Prefoldin; 1.
DR   PROSITE; PS00226; IF_ROD_1; 1.
DR   PROSITE; PS51842; IF_ROD_2; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW   ECO:0000256|RuleBase:RU000685};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233180}.
FT   DOMAIN          112..423
FT                   /note="IF rod"
FT                   /evidence="ECO:0000259|PROSITE:PS51842"
FT   REGION          423..452
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          116..150
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          215..408
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        423..446
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   469 AA;  51328 MW;  546AEEF3496ADD96 CRC64;
     MTTCSRQFTS SSSMKGSFGG GIGGGSSRIS SVLAGGSCRA PSTYGGGLSV SSSRFSSGGA
     YGLGGGYGGG FSSSSSFGSG FGGGYGGGLG AGLGGGLGGG FAGGDGLLVG SEKVTMQNLN
     DRLASYLDKV RALEEANADL EVKIRDWYQR QRPAEIKDYS PYFKTIEDLR NKILTATVDN
     ANVLLQIDNA RLAADDFRTK YETELNLRMS VEADINGLRR VLDELTLARA DLEMQIESLK
     EELAYLKKNH EEEMNALRGQ VGGDVNVEMD AAPGVDLSRI LNEMRDQYEK MAEKNRKDAE
     EWFFTKTEEL NREVATNSEL VQSGKSEISE LRRTVQNLEI ELQSQLSMKA SLENSLEETK
     GRYCMQLAQI QDMIGSVEEQ LAQLRCEMEQ QNQEYKILLD VKTRLEQEIA TYRRLLEGED
     AHLSSSQFSS GSQSSRDVTS SSRQIRTKVM DVHDGKVVST HEQVLRTKN
//