ID A0A2K6LGZ5_RHIBE Unreviewed; 1302 AA.
AC A0A2K6LGZ5;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=Cordon-bleu WH2 repeat protein {ECO:0000313|Ensembl:ENSRBIP00000022815.1};
GN Name=COBL {ECO:0000313|Ensembl:ENSRBIP00000022815.1};
OS Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Rhinopithecus.
OX NCBI_TaxID=61621 {ECO:0000313|Ensembl:ENSRBIP00000022815.1, ECO:0000313|Proteomes:UP000233180};
RN [1] {ECO:0000313|Ensembl:ENSRBIP00000022815.1, ECO:0000313|Proteomes:UP000233180}
RP NUCLEOTIDE SEQUENCE.
RA Wu, C.-I. and Zhang, Y.;
RT "Genome of Rhinopithecus bieti.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSRBIP00000022815.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_017724096.1; XM_017868607.1.
DR Ensembl; ENSRBIT00000046706.1; ENSRBIP00000022815.1; ENSRBIG00000035318.1.
DR GeneID; 108527368; -.
DR CTD; 23242; -.
DR GeneTree; ENSGT00530000063608; -.
DR OrthoDB; 5404619at2759; -.
DR Proteomes; UP000233180; Unplaced.
DR GO; GO:0003785; F:actin monomer binding; IEA:InterPro.
DR CDD; cd21799; WH2_Wa_Cobl; 1.
DR CDD; cd21800; WH2_Wb_Cobl; 1.
DR CDD; cd21801; WH2_Wc_Cobl; 1.
DR InterPro; IPR039895; COBL-like.
DR InterPro; IPR019025; Cordon-bleu_ubiquitin_domain.
DR InterPro; IPR003124; WH2_dom.
DR PANTHER; PTHR47008; PROTEIN CORDON-BLEU; 1.
DR PANTHER; PTHR47008:SF1; PROTEIN CORDON-BLEU; 1.
DR Pfam; PF09469; Cobl; 1.
DR Pfam; PF02205; WH2; 3.
DR SMART; SM00246; WH2; 3.
DR PROSITE; PS51082; WH2; 3.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000233180}.
FT DOMAIN 1150..1170
FT /note="WH2"
FT /evidence="ECO:0000259|PROSITE:PS51082"
FT DOMAIN 1190..1210
FT /note="WH2"
FT /evidence="ECO:0000259|PROSITE:PS51082"
FT DOMAIN 1278..1298
FT /note="WH2"
FT /evidence="ECO:0000259|PROSITE:PS51082"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 243..516
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 699..718
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 822..883
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 948..1000
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1027..1145
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1159..1179
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1221..1276
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 243..275
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 319..335
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 361..386
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 437..464
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 465..479
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 701..716
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 832..865
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1027..1051
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1101..1115
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1161..1176
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1238..1258
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1259..1276
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1302 AA; 140046 MW; 3E647D0E61E4920B CRC64;
MKARAPPPPG KAATLHVHSD QKPPHDGALG SQQNLVRMKE ALRASTVDVT VVLPSGLEKR
SVLNGSHAMM DLLVELCLQN HLNPSHHALE IRSSETQQPL SFKPNTLIGT LNVHTVFVKE
KVPEEKVKPG PPKVPEKSVR LVVNYLRTQK AVVRVSPEVP LQNILPVICA KCEVSPEHVV
LLRDNIAGEE LELSKSLNEL GIKELYAWDN RRETFRKSSL GNDETDKEKK KFLGFFKVNK
RSNSKGCLTT PNSPSMHSRS LTLGPSLSLG SISGVSVKSE MKKRRAPPPP GSGPPVQDKA
SEKVSLGSQI DLQKKKRRAP APPPPQPPPP SPLIPSRTED KEENRKSTMG GGRQVPQKPP
RGTARGPPQL VLPPPPPYPP PDPDVVEPLS FSGEGTGSEA SDQRPKLSLP LGSGSHCSPD
GVPQVLSEAE ETVSVGSCFA SEDTTEDSGV MSSPSDIVSL DSQQDSMKYK DKWATDQEDC
SDQDLAGTPD LGPQKSPLWE KNGFENSHLR TEKAATASND EEDLLITGQF HKTLAELDED
LEEMEDSYET DTSSLTSSIH GTSNHCPQDA MVPHGDTDAI PVTFIGEVSD DPVDSGLFSN
RNNNAGSFDL EGVTSRRASL APLQAEHSQP PGKAREEVPA LHAASHDMGK GIRVALSNIC
KDGNLMEMVP RVTSFASNLH TDNLNAKAKD KVHGCADGER TQATETVNSQ PVNEKEGNDK
NAALAPASWH QRGQNPGKSY RLKHGLTTYK IIPPKSEMRC YNRDVSLSTG AIKIDELGNL
VNPHTAGIRI ISLSSSVPEA ESQPIGKVKE FWRCNSVEKH LGRPLENSAR GPSSPPVRTQ
TQHPESRLQA DPKPILPQQQ SAHHEGLNPL KEGRSQPPTV GMGHVKVPAT HNTEVTFLKP
QRRTSSQYVA SAIAKRIGPP KVHADMVRPH GHAEKGYAGR VPVLAAPPVT VKDDRTSSPH
SETQGWKDGA QRPCVTPPDN HGEDSAVGAP PSREVSSPYR KLYSQDGPAA IHRSSCFSLV
QSSQRDGVSV GQSCGFSGKQ STSNQEANSA SEPRHAPDGT DPPPPHMSNA QSCNRELANG
SVHVPGRGEP SHPPEGSGTE SHILLEREEK PSMFSTDGNE TDSIWPPSIF GPKKKFKPVV
QRPVPKDTSL HSALMEAIHS AGGKDRLRKT AEHTGEGRPV KLSYAEAEGE RSALLAAIRE
HSGTCSLRKV ASSASEELRS FRDAAHSAQG SESPLLEDLG LPPPPAVPPP PPPPSQALSA
PRTASRCSTG TPSNTVDARQ ALMDAIRSGT GAARLRKVPL LV
//
