ID A0A2K6LHB9_RHIBE Unreviewed; 266 AA.
AC A0A2K6LHB9;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=DNA damage regulated autophagy modulator 2 {ECO:0000313|Ensembl:ENSRBIP00000022926.1};
GN Name=DRAM2 {ECO:0000313|Ensembl:ENSRBIP00000022926.1};
OS Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Rhinopithecus.
OX NCBI_TaxID=61621 {ECO:0000313|Ensembl:ENSRBIP00000022926.1, ECO:0000313|Proteomes:UP000233180};
RN [1] {ECO:0000313|Ensembl:ENSRBIP00000022926.1, ECO:0000313|Proteomes:UP000233180}
RP NUCLEOTIDE SEQUENCE.
RA Wu, C.-I. and Zhang, Y.;
RT "Genome of Rhinopithecus bieti.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSRBIP00000022926.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the DRAM/TMEM150 family.
CC {ECO:0000256|ARBA:ARBA00006565}.
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DR RefSeq; XP_017725144.1; XM_017869655.1.
DR RefSeq; XP_017725145.1; XM_017869656.1.
DR RefSeq; XP_017725146.1; XM_017869657.1.
DR RefSeq; XP_017725147.1; XM_017869658.1.
DR AlphaFoldDB; A0A2K6LHB9; -.
DR STRING; 61621.ENSRBIP00000022926; -.
DR Ensembl; ENSRBIT00000046817.1; ENSRBIP00000022926.1; ENSRBIG00000035397.1.
DR GeneID; 108528077; -.
DR CTD; 128338; -.
DR GeneTree; ENSGT01030000234578; -.
DR OMA; CVYIRHR; -.
DR OrthoDB; 2896974at2759; -.
DR Proteomes; UP000233180; Unplaced.
DR GO; GO:0016324; C:apical plasma membrane; IEA:Ensembl.
DR GO; GO:0005794; C:Golgi apparatus; IEA:Ensembl.
DR GO; GO:0005764; C:lysosome; IEA:Ensembl.
DR GO; GO:0001917; C:photoreceptor inner segment; IEA:Ensembl.
DR GO; GO:0045494; P:photoreceptor cell maintenance; IEA:Ensembl.
DR GO; GO:0010506; P:regulation of autophagy; IEA:Ensembl.
DR GO; GO:0007601; P:visual perception; IEA:Ensembl.
DR InterPro; IPR019402; Frag1/DRAM/Sfk1.
DR PANTHER; PTHR21324:SF10; DNA DAMAGE-REGULATED AUTOPHAGY MODULATOR PROTEIN 2; 1.
DR PANTHER; PTHR21324; FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED; 1.
DR Pfam; PF10277; Frag1; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000233180};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..35
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 55..73
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 94..112
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 118..144
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 156..182
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 202..227
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 266 AA; 29710 MW; 9B2E5E16A682FE15 CRC64;
MWWFQQGLSF LPSALVIWTS AAFIFSYITA VTLHHIDPAL PYISDTGTLA PEKCLFGAML
NIAAVLCVAT IYVRYKQVHA LSPEENVIIK LNKAGLVLGI LSCLGLAVVA NFQKTALFAA
HVSGAVLTFG MGSLYMFVQT ILSYQMQPKI HGKQVFWIRL LLVIWCGVSA FSMLTCSSIL
HSGNFGTDLE QKLHWNPEDK GYVLHMITTA AEWSMSFSFF GFFLTYIRDF QKISLRVEAN
LHGLNLYDTA PCPINGERTR LLSRDI
//
