ID   A0A2K6LJG5_RHIBE        Unreviewed;       435 AA.
AC   A0A2K6LJG5;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   RecName: Full=HSF-type DNA-binding domain-containing protein {ECO:0000259|SMART:SM00415};
OS   Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Rhinopithecus.
OX   NCBI_TaxID=61621 {ECO:0000313|Ensembl:ENSRBIP00000023639.1, ECO:0000313|Proteomes:UP000233180};
RN   [1] {ECO:0000313|Ensembl:ENSRBIP00000023639.1, ECO:0000313|Proteomes:UP000233180}
RP   NUCLEOTIDE SEQUENCE.
RA   Wu, C.-I. and Zhang, Y.;
RT   "Genome of Rhinopithecus bieti.";
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSRBIP00000023639.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the HSF family. {ECO:0000256|ARBA:ARBA00006403,
CC       ECO:0000256|RuleBase:RU004020}.
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DR   AlphaFoldDB; A0A2K6LJG5; -.
DR   STRING; 61621.ENSRBIP00000023639; -.
DR   Ensembl; ENSRBIT00000047535.1; ENSRBIP00000023639.1; ENSRBIG00000035744.1.
DR   GeneTree; ENSGT00940000163633; -.
DR   OMA; DCHHMSQ; -.
DR   Proteomes; UP000233180; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR000232; HSF_DNA-bd.
DR   InterPro; IPR027725; HSF_fam.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR10015; HEAT SHOCK TRANSCRIPTION FACTOR; 1.
DR   PANTHER; PTHR10015:SF282; HEAT SHOCK TRANSCRIPTION FACTOR, X-LINKED; 1.
DR   Pfam; PF00447; HSF_DNA-bind; 1.
DR   SMART; SM00415; HSF; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233180}.
FT   DOMAIN          95..211
FT                   /note="HSF-type DNA-binding"
FT                   /evidence="ECO:0000259|SMART:SM00415"
FT   REGION          14..52
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          215..263
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          400..425
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        237..263
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        402..424
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   435 AA;  47904 MW;  C02C30297A72187E CRC64;
     MEDKPSLSVA LCEERNSRGQ GHGLDRVPFP PQLHSETYLH PADPSPAWDD PVSTGSPNFR
     LLTEELAFQA LAEEASFRRP RPDGDIPPQG EDNLLSLPFP QKLWRLVSSN QFSSIWWDEG
     GACIVINQKL FEKEILERDV AHKVFATDSI KSFFRQLNLY GFRKRRQRSF RTLTHVFPAQ
     RPVSILNKLE FYCHPYFQRD SPHLLVRMKR RVGVKSAPGH QEEDKPEAAG SCLAPADTEQ
     QDHTSPNEND QVTPQHQEPV GPNTQIRSVS ALPAIPVMVP DPAMASDNTP VTQPAGEWSE
     GSQAHVTPVA AVPGPAAQPF FSVPKSPTQM NSYGPVVALP TASPSTLAME TTRLPAPGML
     PFCHLWVPVT LVAAGAAQPV ASVAMFPHAL ALHHHCPHSH RTSQYMPASD GPRHTQTTQT
     SAHRGEHLGR ICAGQ
//