ID A0A2K6LNR4_RHIBE Unreviewed; 836 AA.
AC A0A2K6LNR4;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Colony stimulating factor 3 receptor {ECO:0000313|Ensembl:ENSRBIP00000025185.1};
GN Name=CSF3R {ECO:0000313|Ensembl:ENSRBIP00000025185.1};
OS Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Rhinopithecus.
OX NCBI_TaxID=61621 {ECO:0000313|Ensembl:ENSRBIP00000025185.1, ECO:0000313|Proteomes:UP000233180};
RN [1] {ECO:0000313|Ensembl:ENSRBIP00000025185.1, ECO:0000313|Proteomes:UP000233180}
RP NUCLEOTIDE SEQUENCE.
RA Wu, C.-I. and Zhang, Y.;
RT "Genome of Rhinopithecus bieti.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSRBIP00000025185.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the type I cytokine receptor family. Type 2
CC subfamily. {ECO:0000256|ARBA:ARBA00008921}.
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DR RefSeq; XP_017739987.1; XM_017884498.1.
DR RefSeq; XP_017739988.1; XM_017884499.1.
DR RefSeq; XP_017739989.1; XM_017884500.1.
DR RefSeq; XP_017739990.1; XM_017884501.1.
DR AlphaFoldDB; A0A2K6LNR4; -.
DR STRING; 61621.ENSRBIP00000025185; -.
DR Ensembl; ENSRBIT00000049093.1; ENSRBIP00000025185.1; ENSRBIG00000036474.1.
DR GeneID; 108537272; -.
DR KEGG; rbb:108537272; -.
DR CTD; 1441; -.
DR GeneTree; ENSGT00940000158915; -.
DR OrthoDB; 5354422at2759; -.
DR Proteomes; UP000233180; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004896; F:cytokine receptor activity; IEA:InterPro.
DR CDD; cd00063; FN3; 4.
DR Gene3D; 2.60.40.10; Immunoglobulins; 6.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR003529; Hematopoietin_rcpt_Gp130_CS.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR010457; IgC2-like_lig-bd.
DR PANTHER; PTHR23036; CYTOKINE RECEPTOR; 1.
DR PANTHER; PTHR23036:SF103; GRANULOCYTE COLONY-STIMULATING FACTOR RECEPTOR; 1.
DR Pfam; PF00041; fn3; 1.
DR Pfam; PF06328; Lep_receptor_Ig; 1.
DR SMART; SM00060; FN3; 5.
DR SUPFAM; SSF49265; Fibronectin type III; 4.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR PROSITE; PS50853; FN3; 4.
DR PROSITE; PS01353; HEMATOPO_REC_L_F2; 1.
PE 3: Inferred from homology;
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000233180};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..836
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014348998"
FT TRANSMEM 626..650
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 233..332
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 334..430
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 431..528
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 530..623
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
SQ SEQUENCE 836 AA; 92167 MW; 26925E610DA78549 CRC64;
MARLRTCSLT WAALIILLLP GSLEECGHVS VSAPIVHLGD PITASCIIKQ NCSHLDLEPQ
ILWRLGAELQ PGGRQQRLSD GTQQSTITLP HLNHTRAFLS CCLNWGNSLQ ILDQVELRAG
YPPAIPRNLS CLMNLTTSSL ICQWEPGPET HLPTSFTLKS FKSRGNCQTQ GDSILDCVPE
DGQSHCSIPR RHLLLYQNMG IWVQAENALG TSMSPQLCLQ PMDVVKLEPP MLRTMDPSPE
AAPPQAGCLQ LCWEPWQPAL HINQKCELRH KPQSGEASWA LVGPLPLEAL RYELCGLLPA
TAYTLQIRCI RWPLPGHWSD WSPSLELRTT ERAPTVRLNT WWRQRQLDPR TVQLFWKPVP
LEEDSGQIQG YVVSWRPSGQ AGAILPLCNT TELSCTFPLP SEAQEVALVA YNSAGTSRPT
PVVFSESRGP ALTRLHAMAQ DPHSLWVGWE PPSPWPQGYV IEWGLSPPST SNSNKTWRME
QNGSATGFLL QENIRPFQLY EITVTPLYQD AMGPSQHVYA YSQEMAPCHA PELHLKHIGK
TWAQLEWVPE PPELGKSPLT HYTIFWTNTQ NQSFSTILNA SSHGFVLHGL EPASLYHIHL
MAASQAGATN STVLTLMTLI PEGSELHILL GLFGLLLLLS CLCGTAWLCC SPSRKNPLWP
SVPDPAHSSL GSWVPTIMEE EAFQLPGLGM PPITKLTVLE EDEKKPLPWE SHNSSETCGL
PTLVQTYVLQ GDPRAAPAQP QSQSGTSDQV LYGQLLGSPT SPGPGHYLRC DSTQPLLAGL
TPSPKSYENL WFQASPLGTL VTPAPSQEDD CVFGPLLDFP LLQGIRVHGV EGLESF
//
