ID A0A2K6LSQ7_RHIBE Unreviewed; 1483 AA.
AC A0A2K6LSQ7;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=ATP binding cassette subfamily A member 10 {ECO:0000313|Ensembl:ENSRBIP00000026566.1};
GN Name=ABCA10 {ECO:0000313|Ensembl:ENSRBIP00000026566.1};
OS Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Rhinopithecus.
OX NCBI_TaxID=61621 {ECO:0000313|Ensembl:ENSRBIP00000026566.1, ECO:0000313|Proteomes:UP000233180};
RN [1] {ECO:0000313|Ensembl:ENSRBIP00000026566.1, ECO:0000313|Proteomes:UP000233180}
RP NUCLEOTIDE SEQUENCE.
RA Wu, C.-I. and Zhang, Y.;
RT "Genome of Rhinopithecus bieti.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSRBIP00000026566.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR STRING; 61621.ENSRBIP00000026566; -.
DR Ensembl; ENSRBIT00000050483.1; ENSRBIP00000026566.1; ENSRBIG00000037149.1.
DR GeneTree; ENSGT00940000162673; -.
DR OMA; LCKEQEM; -.
DR Proteomes; UP000233180; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0006869; P:lipid transport; IEA:UniProt.
DR CDD; cd03263; ABC_subfamily_A; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR026082; ABCA.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR19229:SF270; ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 10; 1.
DR PANTHER; PTHR19229; ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA; 1.
DR Pfam; PF01061; ABC2_membrane; 1.
DR Pfam; PF12698; ABC2_membrane_3; 1.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000233180};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 74..93
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 105..126
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 146..168
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 180..204
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 210..230
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 277..300
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 739..756
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 896..917
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 953..974
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 980..1008
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1015..1037
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 361..597
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 1144..1380
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 1094..1118
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1483 AA; 168833 MW; 689B4C903EA268C5 CRC64;
MIIYLYFSYM VGRTVIGTPD EETMDIVLPK KYHQMVGVIF RDTFSYQLKF NWGYRIPIIK
EHSEYTGNCT KTDYNLFLIL HGIPFIGINM KMLPFLSKGE IMNEWFLFTC LVSFSSFIYF
ASLNVARERG EFKKLMTVMG LRESAFWLSW GLTYVCFIFV MSIFMALIIT SIPIIFHTGF
MVIFTLFSLY GLSLIALAFL MSVLIRKPML AGLAGFLFAV FWGCLGFTVL HRQLPLSLGW
VLSLFSPFAF IAGMDQITHL DHYLRGVIFP GPSGDSYIMI ATFFILAFDA LFYLILTLYF
ERVLPDKDGH GDSPLFFLKS SFWSKHQNTH HEIFENEMNS ENSSDDSFEP VSPEFHGKEA
IRIRNVKKEY NGKTGKVEAL QGIFFDIYEG QITAILGHDG AGKSTLLNIL SGLSVSTEGS
TTIYNTQLSE ITDMEEIRQN IGFCPQFNFQ FDFLTVRENL RVFAKIKGIQ PKEFFFDMVK
RIIMELDMQS IQDIIAKKLS GGQKRKLTLG IAILGDPQVL LLDEPTAGLD PFLRHRVWSL
LKEHKVDRVI LFSTQFMDEA DILADRKVFL SKGKLKCAGS SLFLKRKWGI GYHLSLHRNE
MCDTEKITSL IKQHIPDAKL TTESEENLPL EKTNRFPDLY SDLDKCSDQG IRNYATAPGL
NEVFLNLEGK SAIDEPDFDI GKQKKIYVTR NTGNESEMEQ VLCSLPETRK AVSSATLWRR
QIYAVATLRF LKLRRERRVL LCLSLVLGVA FIPIILEKIM YKVLRETHCW EFSPTMYFLS
LEQIPKMPLT SLLIINNTGS NIEDLVHSLK RQDIVLEIDD FRNRNGSDDP SYNGAIIVSG
DQKDYRFSVA CNTKKLNCFP VLMGIVSNAL TGIFNFTELI QTESTSFSRD DIVLDFGFID
GSIFLLLITN CISPFIGMSS ISDYKKKVQS QLWISGLWPS AYWCGQALVD IPLYFLILLS
IHLIYYFIFL GFQLSWERTF VLVVCIIGCT ASLIFLTYIL ICVTTILVST QYENLNLILC
MIFIPSFTLL GYVILLIQLD FMYMTNLDSL DSRINEVNKT ILLTTLISGV SFFVIRCLER
SMEMKYMNKD PVLISPRSRE THPNPEEPEE EDEDVQAERV QAANTLTTPN LAEEPVITAS
CLHKEYYDTK KSCFSTRKKK IAIRNVSFCV KKGEVLGLLG HNGAGKSTSI KMIAGYTKPC
AGVVVLQDSR TSVRQQHDNS LKFLGYCPEE NSLWPTLTMK EHLELYAAVK GLDKDDAALS
ISRLVEALEL QEQLKAPVKT LSEGIKRKLC FVLSILGNPS VVLLDEPFTG MDPEGQQQIQ
ILQATVKNKE RGALLTTHYM SEAEAVCDRV AIMVSGTLRC IGSIQQLKNK FGKDYLLEIK
MKEPSQVEAL HTEILKLFPQ AARQERYSSL MAYKLPVEDV HPLSRAFFKL EAVKQTFNLE
EYSLSQATLE QVFLELCKEQ EMGNVDDKID TTVQWKLLPQ EDP
//
