ID A0A2K6LUJ8_RHIBE Unreviewed; 1330 AA.
AC A0A2K6LUJ8;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Sushi, nidogen and EGF like domains 1 {ECO:0000313|Ensembl:ENSRBIP00000027210.1};
GN Name=SNED1 {ECO:0000313|Ensembl:ENSRBIP00000027210.1};
OS Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Rhinopithecus.
OX NCBI_TaxID=61621 {ECO:0000313|Ensembl:ENSRBIP00000027210.1, ECO:0000313|Proteomes:UP000233180};
RN [1] {ECO:0000313|Ensembl:ENSRBIP00000027210.1, ECO:0000313|Proteomes:UP000233180}
RP NUCLEOTIDE SEQUENCE.
RA Wu, C.-I. and Zhang, Y.;
RT "Genome of Rhinopithecus bieti.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSRBIP00000027210.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR Ensembl; ENSRBIT00000051137.1; ENSRBIP00000027210.1; ENSRBIG00000037462.1.
DR GeneTree; ENSGT00940000160730; -.
DR Proteomes; UP000233180; Unplaced.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0007160; P:cell-matrix adhesion; IEA:InterPro.
DR CDD; cd00033; CCP; 1.
DR CDD; cd00054; EGF_CA; 13.
DR CDD; cd00063; FN3; 3.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR Gene3D; 2.10.25.10; Laminin; 14.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR013032; EGF-like_CS.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003886; NIDO_dom.
DR InterPro; IPR035976; Sushi/SCR/CCP_sf.
DR InterPro; IPR000436; Sushi_SCR_CCP_dom.
DR PANTHER; PTHR24033; EGF-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24033:SF151; PROTEIN EYES SHUT; 1.
DR Pfam; PF00008; EGF; 9.
DR Pfam; PF00041; fn3; 3.
DR Pfam; PF12661; hEGF; 4.
DR Pfam; PF06119; NIDO; 1.
DR PRINTS; PR00010; EGFBLOOD.
DR SMART; SM00032; CCP; 1.
DR SMART; SM00181; EGF; 14.
DR SMART; SM00179; EGF_CA; 13.
DR SMART; SM00060; FN3; 3.
DR SMART; SM00539; NIDO; 1.
DR SUPFAM; SSF57535; Complement control module/SCR domain; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 10.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR PROSITE; PS00010; ASX_HYDROXYL; 5.
DR PROSITE; PS00022; EGF_1; 13.
DR PROSITE; PS01186; EGF_2; 12.
DR PROSITE; PS50026; EGF_3; 14.
DR PROSITE; PS01187; EGF_CA; 2.
DR PROSITE; PS50853; FN3; 3.
DR PROSITE; PS51220; NIDO; 1.
DR PROSITE; PS50923; SUSHI; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000233180};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Sushi {ECO:0000256|ARBA:ARBA00022659, ECO:0000256|PROSITE-
KW ProRule:PRU00302}.
FT DOMAIN 95..254
FT /note="NIDO"
FT /evidence="ECO:0000259|PROSITE:PS51220"
FT DOMAIN 264..306
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 327..363
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 365..401
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 407..443
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 446..478
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 519..555
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 558..594
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 597..633
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 635..671
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 674..731
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 731..767
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 769..805
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 807..843
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 845..881
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 886..984
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 985..1083
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1084..1178
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1252..1288
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 353..362
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 391..400
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 433..442
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 468..477
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 545..554
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 584..593
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 623..632
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 661..670
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 702..729
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 757..766
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 795..804
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 833..842
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 871..880
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1278..1287
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 1330 AA; 143415 MW; 05D4CFEC1924C0DB CRC64;
LQFGVAWPTC LVARPWARAG GVCAARWLLA ELYRFRRERR RRRHPQTERT GGFRGLPASS
VPFPFFGAKN NNKIVTFWEV SQFTPVALPH VPRTAVCGSL RQMRETGVQA MCTTGGHRPS
HACRRATEDV RHYFPELLDF NATWVFVATW YRVTFFGGSS SSPVNTFQTV LITDGKFSFT
IFNYESIVWT TGTHASSGGN ATGLGGIAAQ AGFNAGDGQR YFSIPGSRTA DMAEVETTTN
VGVPGRWAFR IDDAQVRVGG CGHTTSVCLT LRPCLNGGKC IDDCVTGNPS YTCSCLSGFT
GRSGCAGLRR NAVGSTTPRG HCPQGVAQSP CDTRECQNGG QCQVENGSAV CVCQAGYTGA
ACETDMDDCS PDPCLNGGSC VDLVGNYTCL CAEPFKGLHC ETGDHPVPDA CLSAPCHNGG
TCVDADQGYV CECPEGFMGL DCRQRVPNDC ECRNGGRCLG ANTTLCQCPP GFFGLLCEFE
ITAMPCNMNT QCPDGGYCME HGGSYLCVCH TDHNASHSLP SPCDSDPCFN GGSCDAHDDS
YICECPRGFH GKHCEKARPH LCSSGPCRNG GTCKEAGGEY HCSCPYRFTG RHCEIGKPDS
CASGPCHNGG TCFHYIGKYK CDCPPGFSGR HCEIAPSPCF RSPCVNGGTC EDRGTDFFCH
CQAGYMGRRC QAEVDCGPPE EVKHATLRFN GTRLGAVALY ACDRGYSLSA PSRIRVCQPH
GVWSEPPQCL EIDECRSQPC LHGGSCQDHV AGYLCLCSTG YQGVHCELER DECRAHLCRN
GGSCRNLPGA YVCQCPAGFV GVHCETEVDA CDSSPCQHGG RCESGGGAYL CVCPEGFFGY
HCETASDPCF SSPCGGRGYC LASNGSHSCT CKVGYTGKDC AKELFPPTAL KMERVEESGV
SISWNPPDGP AARQMLDGYA VTYVSSDGSY RRTDFVDRTR SSHQLRALAA GRAYNISVFS
VKRNTNNKND ISRPAVLLAR TRPRPVEGFE VTNVTASTIS VQWALHRIHH ATVSGVRVSI
RHPEALGDQA TDVERSVDRF TFGALLPGRR YTIQLTTLSG LRGEEHPTES LATAPTHVWT
RPLPPANLTA ARVTATSAHV VWDAPTPGSL LEAYVINVTT SQSTKSRYVP NGKLASYTVR
DLLPGRRYQL SVTAVQGTEL GPLHSEPAHL YIITSPRDGA DRRWHQGGHH PRVLRNRPPP
ARLPELRLLN DHSVPETPTQ PPRFSELVDG RGRVSARFGS SPSKAATVRS QVPGNCSENL
CQNGGTCVPG ADAHSCDCGP GFKGRRCELA CIKVSRPCTR LFSETKSFPV WEGGVCHHVK
QSKSQTLEKS
//
