ID A0A2K6LUY2_RHIBE Unreviewed; 605 AA.
AC A0A2K6LUY2;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=Glycerophosphodiester phosphodiesterase domain containing 5 {ECO:0000313|Ensembl:ENSRBIP00000027331.1};
GN Name=GDPD5 {ECO:0000313|Ensembl:ENSRBIP00000027331.1};
OS Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Rhinopithecus.
OX NCBI_TaxID=61621 {ECO:0000313|Ensembl:ENSRBIP00000027331.1, ECO:0000313|Proteomes:UP000233180};
RN [1] {ECO:0000313|Ensembl:ENSRBIP00000027331.1, ECO:0000313|Proteomes:UP000233180}
RP NUCLEOTIDE SEQUENCE.
RA Wu, C.-I. and Zhang, Y.;
RT "Genome of Rhinopithecus bieti.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSRBIP00000027331.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the glycerophosphoryl diester phosphodiesterase
CC family. {ECO:0000256|ARBA:ARBA00007277}.
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DR RefSeq; XP_017740710.1; XM_017885221.1.
DR AlphaFoldDB; A0A2K6LUY2; -.
DR STRING; 61621.ENSRBIP00000027331; -.
DR Ensembl; ENSRBIT00000051262.1; ENSRBIP00000027331.1; ENSRBIG00000037527.1.
DR GeneID; 108537612; -.
DR CTD; 81544; -.
DR GeneTree; ENSGT00940000159690; -.
DR OMA; CKHCRYR; -.
DR OrthoDB; 203377at2759; -.
DR Proteomes; UP000233180; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008081; F:phosphoric diester hydrolase activity; IEA:InterPro.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR CDD; cd08608; GDPD_GDE2; 1.
DR Gene3D; 3.20.20.190; Phosphatidylinositol (PI) phosphodiesterase; 1.
DR InterPro; IPR030395; GP_PDE_dom.
DR InterPro; IPR017946; PLC-like_Pdiesterase_TIM-brl.
DR PANTHER; PTHR23344:SF6; GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE DOMAIN-CONTAINING PROTEIN 5; 1.
DR PANTHER; PTHR23344; GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE; 1.
DR Pfam; PF03009; GDPD; 1.
DR Pfam; PF13653; GDPD_2; 1.
DR SUPFAM; SSF51695; PLC-like phosphodiesterases; 1.
DR PROSITE; PS51704; GP_PDE; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000233180};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 43..63
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 90..114
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 126..143
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 163..181
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 193..213
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 498..517
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 228..485
FT /note="GP-PDE"
FT /evidence="ECO:0000259|PROSITE:PS51704"
SQ SEQUENCE 605 AA; 68597 MW; 95AFEAAFC6056718 CRC64;
MVRHQPLQYY EPQLCLSCLT GIYGCRWKRY QRSHDDTTPW ERLWFLLLTF TFGLTLTWLY
FWWEVHNDYD EFNWYLYNRM GYWSDWPVPI LVTTAAAFAY IAGLLVLALC HIAVGQQMNL
HWLHKIGLVV ILASTVVAMS AVAQLWEDEW EVLLISLQGT APFLHVGALA AVTVLSWIVA
GQFARAERTS SQVTILCTFF TVVFALYLAP LTISSPCIME KKDLGPKPAL IGHRGAPMLA
PEHTLMSFRK ALEQKLYGLQ ADITISLDGV PFLMHDATLR RTTNVEEEFP ELARRPASML
NWTTLQRLNA GQWFLKTDPF WTASSLSPSD HREAQNQSIC SLAELLELAK GNATLLLNLR
DPPREHPYRN SFLNVTLEAV LHSGFPQHQV MWLPSRQRPL VRKVAPGFQQ TSGSKEAVTS
LRRGHIQRLN LRYTQVSRQE LRDYASWNLS VNLYTVNAPW LFSLLWCAGV PSVTSDNSHT
LSQVPSPLWI MPPDEYCLMW VTADLVSFTL IVGIFVLQKW RLGGIRSYNP EQIMLSAAVR
RTSRDVSIMK EKLIFSEISD GVEISDVLSV CSDNSYDTYA NSTATTVGPR GGGSCTKTLT
ERSGR
//
