ID   A0A2K6LZL2_RHIBE        Unreviewed;       649 AA.
AC   A0A2K6LZL2;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Sorbin and SH3 domain containing 2 {ECO:0000313|Ensembl:ENSRBIP00000028967.1};
GN   Name=SORBS2 {ECO:0000313|Ensembl:ENSRBIP00000028967.1};
OS   Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Rhinopithecus.
OX   NCBI_TaxID=61621 {ECO:0000313|Ensembl:ENSRBIP00000028967.1, ECO:0000313|Proteomes:UP000233180};
RN   [1] {ECO:0000313|Ensembl:ENSRBIP00000028967.1, ECO:0000313|Proteomes:UP000233180}
RP   NUCLEOTIDE SEQUENCE.
RA   Wu, C.-I. and Zhang, Y.;
RT   "Genome of Rhinopithecus bieti.";
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSRBIP00000028967.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A2K6LZL2; -.
DR   Ensembl; ENSRBIT00000052914.1; ENSRBIP00000028967.1; ENSRBIG00000038356.1.
DR   GeneTree; ENSGT00940000157056; -.
DR   Proteomes; UP000233180; Unplaced.
DR   CDD; cd11923; SH3_Sorbs2_2; 1.
DR   Gene3D; 2.30.30.40; SH3 Domains; 3.
DR   InterPro; IPR036028; SH3-like_dom_sf.
DR   InterPro; IPR001452; SH3_domain.
DR   InterPro; IPR003127; SoHo_dom.
DR   PANTHER; PTHR14167:SF56; DREBRIN-LIKE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR14167; SH3 DOMAIN-CONTAINING; 1.
DR   Pfam; PF00018; SH3_1; 1.
DR   Pfam; PF07653; SH3_2; 1.
DR   Pfam; PF14604; SH3_9; 1.
DR   Pfam; PF02208; Sorb; 1.
DR   PRINTS; PR00499; P67PHOX.
DR   PRINTS; PR00452; SH3DOMAIN.
DR   SMART; SM00326; SH3; 3.
DR   SMART; SM00459; Sorb; 1.
DR   SUPFAM; SSF50044; SH3-domain; 3.
DR   PROSITE; PS50002; SH3; 3.
DR   PROSITE; PS50831; SOHO; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000233180};
KW   SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW   ProRule:PRU00192}.
FT   DOMAIN          152..217
FT                   /note="SoHo"
FT                   /evidence="ECO:0000259|PROSITE:PS50831"
FT   DOMAIN          408..471
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
FT   DOMAIN          487..548
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
FT   DOMAIN          590..649
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
FT   REGION          1..44
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          58..82
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          218..409
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        63..82
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        218..239
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        242..257
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        258..288
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        301..321
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        346..380
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   649 AA;  72136 MW;  4E48F477D506376C CRC64;
     MSVTLTSVKR VQSSPNLLAA GRDSQSPDSA WRSYNDGNQE TLNGDATYSS LAAKGFRSVR
     PNLQDKRSPT QSQITVNGNS GGAVSPMSYY QRPFSPSAYS LPASLNSSIV MQHGSSLDST
     GTYPQHAHSL DGTTSSSIPL YRSSEEEKRV TVIKAPHYPG IGPVDESGIP TAIRTTVDRP
     KDWYKTMFKQ IHMVHKPGMF AGYTHLLYSA QSHPAAKTQT YRPLSKSHSD NSTNAFKDVS
     SPVPPPHVPP PVPPLRPRDR SSTEKHDWDP PDRKVDTRKF RSEPRSIFEY EPGKSSILQH
     ERPASLYQSS IDRSLERPMS SASMASDFRK RRKSEPAVGP PRGLGDQSVS RTSPGRADLP
     GSSTTLTKSF TSSSPSSPSR AKDRESPRSY SSTLTDTGRS APRERRGTPE KEVVNLIAWE
     SFTATHLIGE LSFKKGDTVY ILRKIDQNWY EGEHHGRVGI FPISYVEKLT PPEKAQPARP
     PPPAQPGEIG EAVAKYNFNA DTNVELSLRK GDRVILLKRV DQNWYEGKIP GTNRQGIFPV
     SYVEVVKKNT KGAEDYPDPP IPHSYSSDRI HSLSSNKPQR PVFTHENIQG GGEPFQALYN
     YTPRNEDELE LRESDVIDVM EKCDDGWFVG TSRRTKFFGT FPGNYVKRL
//