ID A0A2K6M188_RHIBE Unreviewed; 1172 AA.
AC A0A2K6M188;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Laminin subunit beta 3 {ECO:0000313|Ensembl:ENSRBIP00000029542.1};
GN Name=LAMB3 {ECO:0000313|Ensembl:ENSRBIP00000029542.1};
OS Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Rhinopithecus.
OX NCBI_TaxID=61621 {ECO:0000313|Ensembl:ENSRBIP00000029542.1, ECO:0000313|Proteomes:UP000233180};
RN [1] {ECO:0000313|Ensembl:ENSRBIP00000029542.1, ECO:0000313|Proteomes:UP000233180}
RP NUCLEOTIDE SEQUENCE.
RA Wu, C.-I. and Zhang, Y.;
RT "Genome of Rhinopithecus bieti.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSRBIP00000029542.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00460}.
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DR RefSeq; XP_017743801.1; XM_017888312.1.
DR AlphaFoldDB; A0A2K6M188; -.
DR STRING; 61621.ENSRBIP00000029542; -.
DR Ensembl; ENSRBIT00000053493.1; ENSRBIP00000029542.1; ENSRBIG00000038657.1.
DR GeneID; 108539549; -.
DR KEGG; rbb:108539549; -.
DR CTD; 3914; -.
DR GeneTree; ENSGT00940000160731; -.
DR OMA; RCLCLPH; -.
DR OrthoDB; 90222at2759; -.
DR Proteomes; UP000233180; Unplaced.
DR GO; GO:0005610; C:laminin-5 complex; IEA:Ensembl.
DR GO; GO:0050873; P:brown fat cell differentiation; IEA:Ensembl.
DR GO; GO:0035987; P:endodermal cell differentiation; IEA:Ensembl.
DR CDD; cd22303; cc_LAMB3_C; 1.
DR CDD; cd00055; EGF_Lam; 6.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 2.10.25.10; Laminin; 4.
DR Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR Gene3D; 2.170.300.10; Tie2 ligand-binding domain superfamily; 1.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR008211; Laminin_N.
DR InterPro; IPR002049; LE_dom.
DR PANTHER; PTHR10574:SF268; LAMININ SUBUNIT BETA-3; 1.
DR PANTHER; PTHR10574; NETRIN/LAMININ-RELATED; 1.
DR Pfam; PF00053; Laminin_EGF; 6.
DR Pfam; PF00055; Laminin_N; 1.
DR PRINTS; PR00011; EGFLAMININ.
DR SMART; SM00180; EGF_Lam; 6.
DR SMART; SM00136; LamNT; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 5.
DR PROSITE; PS00022; EGF_1; 1.
DR PROSITE; PS01248; EGF_LAM_1; 2.
DR PROSITE; PS50027; EGF_LAM_2; 6.
DR PROSITE; PS51117; LAMININ_NTER; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00460};
KW Laminin EGF-like domain {ECO:0000256|ARBA:ARBA00023292,
KW ECO:0000256|PROSITE-ProRule:PRU00460};
KW Reference proteome {ECO:0000313|Proteomes:UP000233180};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..1172
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014394381"
FT DOMAIN 22..249
FT /note="Laminin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51117"
FT DOMAIN 250..315
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 316..378
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 379..430
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 431..480
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 481..533
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 534..580
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT REGION 747..766
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 839..873
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 949..979
FT /evidence="ECO:0000256|SAM:Coils"
FT DISULFID 281..290
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 346..355
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 401..410
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 453..462
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 481..493
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 483..500
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 502..511
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 534..546
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 536..553
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 555..564
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
SQ SEQUENCE 1172 AA; 129442 MW; ADB961A58413C5FA CRC64;
MRPLFLLCFA LPGLLHAQQA CSRGACYPPV GDLLVGRTRF LRASSTCGLT KPETYCTQHG
EWQMKCCKCD SRQPHNYYSH RVENVASSSG PMRWWQSQND VNPVSLQLDL DRRFQLQEVM
MEFQGPMPAG MLIERSSDFG NTWRVYQYLA ADCTSTFPRV RQGRPQSWQD VRCQFLPQRP
NARLNGGKVQ LNLMDLASGI PATQSKKIQE LGEITNLRVN FTRLAPVPQR GYHPPSAYYA
VSQLRLQGSC FCHGHADRCA PKPGASAGPS TAVQVHDVCV CQHNTAGPNC EHCAPFYNNR
PWRPAEGQDT HECQRCDCNG HSETCHFDPA VFAASQGAYG GVCDNCQDHT EGKNCERCQL
HYFRNRRPGA SIQETCIPCE CDPDGAVPGA PCDPVTGQCV CKEHVQGERC DLCKPGFTGL
TYANPQGCHR CDCNILGSRR DMPCDEESGR CLCLPNVVGP KCDQCAPYHW KLASGQGCEP
CACDPHNSLS PQCNQFTGQC PCREGFGGLT CSAAAIRQCP DRTYGDAATG CRACDCDFRG
TEGPGCDKAS GRCLCRPGLT GPRCDQCQRG YCNRYPVCVA CHPCFQTYDA DLREQALRLG
SLRNATASLW SGPGLEDRGL ASRILDAKSK IEQIRAVLSS AAVTEQEVAQ VASAILSLRR
ALQGLQPDLP LEEETLSLPR DLESLDRSFN GLLTMYQRKR EQFEKLSSAD PSGAFRMLTT
AYEQSAQAVQ QVSDSSRLLD QLRDSRREAE RLAQQAGGGG GTGSPQLVAL RLEMSSLPDL
TPTFNKLCGS SRQMACTPGS CPGELCPHDN GTACGSHCRG VLPRAGGAFW MAGQVAEQLR
GFNAQLQQTR QMIRAAEESA SQIQSNAQRL ETQVSTSRSQ MEEDVRRTRL LIQQVRDFLT
DPDTDAATIQ EVSEAVLALW LPTDSATVLQ KMNEIQAIAA RLPNVDLVLS QTKQDIARAR
RLQAEAEEAR SRAHAVEGQV EDVVGNLQQG TVALQEAQDT MQGTSRSLRL IQDRVAEVQQ
VLQPAEKLVT SMTKQLGDFW TRMEELRRQA WQQRAQAVQA QQLAEGASEQ ALSAQEGFER
IKQKYAELKD RLGQSPTLGE QGARIQSVKT EAEELFGETM EMMDRMKDME LELLRGSQAI
MLRSADLTGL EKRVEQIRDH INERVLYYAT CK
//
