ID A0A2K6MDH2_RHIBE Unreviewed; 344 AA.
AC A0A2K6MDH2;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE SubName: Full=G protein-coupled receptor class C group 5 member D {ECO:0000313|Ensembl:ENSRBIP00000033790.1};
GN Name=GPRC5D {ECO:0000313|Ensembl:ENSRBIP00000033790.1};
OS Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Rhinopithecus.
OX NCBI_TaxID=61621 {ECO:0000313|Ensembl:ENSRBIP00000033790.1, ECO:0000313|Proteomes:UP000233180};
RN [1] {ECO:0000313|Ensembl:ENSRBIP00000033790.1, ECO:0000313|Proteomes:UP000233180}
RP NUCLEOTIDE SEQUENCE.
RA Wu, C.-I. and Zhang, Y.;
RT "Genome of Rhinopithecus bieti.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSRBIP00000033790.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR RefSeq; XP_017728526.1; XM_017873037.1.
DR AlphaFoldDB; A0A2K6MDH2; -.
DR STRING; 61621.ENSRBIP00000033790; -.
DR Ensembl; ENSRBIT00000057772.1; ENSRBIP00000033790.1; ENSRBIG00000040632.1.
DR GeneID; 108530258; -.
DR KEGG; rbb:108530258; -.
DR CTD; 55507; -.
DR GeneTree; ENSGT00950000182961; -.
DR OMA; QEYFIPR; -.
DR OrthoDB; 4263681at2759; -.
DR Proteomes; UP000233180; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR CDD; cd15279; 7tmC_RAIG1_4_GPRC5A_D; 1.
DR InterPro; IPR017978; GPCR_3_C.
DR PANTHER; PTHR14511; G PROTEIN COUPLED RECEPTOR, CLASS C, GROUP 5; 1.
DR PANTHER; PTHR14511:SF16; G-PROTEIN COUPLED RECEPTOR FAMILY C GROUP 5 MEMBER D; 1.
DR Pfam; PF00003; 7tm_3; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000233180};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 22..47
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 59..82
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 94..115
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 127..150
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 170..193
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 205..224
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 244..266
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 18..261
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|Pfam:PF00003"
SQ SEQUENCE 344 AA; 38845 MW; 5D73DF7A833E5C79 CRC64;
MYKDCIKSTG DYFLPCDSEG PWGIILESLA ILGIVVTILL LLAFLFLMRK IQDCSQWNVL
PTQLLFLLSV LGLFGLTFAF IIQLNQQTAP VRYFLFGVLF ALCFSCLLAH ASNLVKLVRG
RVSFSWTTIL CIAIGCSLLQ VIIAIEYVTL IMTRGMMFVH MTPCQLNVDF VVLLVYVLFL
MALTFFVSKA TFCGPCENWK QHGRLIFITV LFSIIIWVVW ISMLLRGNPQ FQRQPQWDDP
VVCIALVTNA WVFLLLYIVP ELCILYRSCR QECPSQGHAC PVTAYQHSFQ VENQELSRAR
DSDGAEEDVA LTSFGTPIQP QTVDPTQECF IPRAKLSPQQ DAGV
//
