ID A0A2K6MIR5_RHIBE Unreviewed; 663 AA.
AC A0A2K6MIR5;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=EF-hand domain-containing protein {ECO:0000259|PROSITE:PS50222};
OS Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Rhinopithecus.
OX NCBI_TaxID=61621 {ECO:0000313|Ensembl:ENSRBIP00000035669.1, ECO:0000313|Proteomes:UP000233180};
RN [1] {ECO:0000313|Ensembl:ENSRBIP00000035669.1, ECO:0000313|Proteomes:UP000233180}
RP NUCLEOTIDE SEQUENCE.
RA Wu, C.-I. and Zhang, Y.;
RT "Genome of Rhinopithecus bieti.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSRBIP00000035669.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A2K6MIR5; -.
DR STRING; 61621.ENSRBIP00000035669; -.
DR Ensembl; ENSRBIT00000059667.1; ENSRBIP00000035669.1; ENSRBIG00000041472.1.
DR GeneTree; ENSGT00940000166468; -.
DR OMA; VITIRSW; -.
DR Proteomes; UP000233180; Unplaced.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0045104; P:intermediate filament cytoskeleton organization; IEA:InterPro.
DR CDD; cd00051; EFh; 1.
DR CDD; cd00176; SPEC; 2.
DR Gene3D; 1.20.58.60; -; 5.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR043197; Plakin.
DR InterPro; IPR018159; Spectrin/alpha-actinin.
DR InterPro; IPR002017; Spectrin_repeat.
DR PANTHER; PTHR23169; ENVOPLAKIN; 1.
DR PANTHER; PTHR23169:SF25; MICROTUBULE-ACTIN CROSS-LINKING FACTOR 1, ISOFORMS 1_2_3_4_5; 1.
DR Pfam; PF13499; EF-hand_7; 1.
DR Pfam; PF00435; Spectrin; 4.
DR SMART; SM00054; EFh; 2.
DR SMART; SM00150; SPEC; 5.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF46966; Spectrin repeat; 4.
DR PROSITE; PS00018; EF_HAND_1; 2.
DR PROSITE; PS50222; EF_HAND_2; 2.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000233180};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..663
FT /note="EF-hand domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014376919"
FT DOMAIN 572..607
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 608..643
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REGION 482..512
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 663 AA; 77432 MW; 9E2679EA5FF825DF CRC64;
MPLYLTLSLK RALLFLQVFA NEVNAHRDQI IELDQTGNQL KFLSQKQDVV LIKNLLVSVQ
SRWEKVVQRS IERGRSLDDA RKRAKQFHEA WKKLIDWLED AESHLDSELE ISNDPDKIKL
QLSKHKEFQK TLGGKQPVYD TTIRTGRALK EKTLLPEDTQ KLDNFLGEVR DKWDTVCGKS
VERQHKLEEA LLFSGQFMDA LQALVDWLYK VEPQLAEDQP VHGDLDLVMN LMDAHKVFQK
ELGKRTGTVQ VLKRSGRELI ENSRDDTTWV KGQLQELSTR WDTVCKLSVS KQSRLEQALK
QAEVFRDTVH MLLEWLSEAE QTLRFRGALP DDTEALQSLI DTHKEFMKKV EEKRVDVNSA
VAMGEVILAV CHPDCITTIK HWITIIRARF EEVLTWAKQH QQRLETALSE LVANAELLEE
LLAWIQWAET TLIQRDQEPI PQNIDRVKAL IAEHQTFMEE MTRKQPDVDR VTKTYKRKNI
EPTHAPFIEK SRSGGRKSLS QPTPPPMPIL SQSEAKNPRI NQLSARWQQV WLLALERQRK
LNDALDRLEE LKEFANFDFD VWRKKYMRWM NHKKSRVMDF FRRIDKDQDG KITRQEFIDG
ILASKFPTTK LEMTAVADIF DRDGDGYIDY YEFVAALHPN KDAYRPTTDA DKIEDEVREI
IIF
//
