ID A0A2K6MSU0_RHIBE Unreviewed; 562 AA.
AC A0A2K6MSU0;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=APOBEC1 complementation factor {ECO:0000313|Ensembl:ENSRBIP00000038817.1};
GN Name=A1CF {ECO:0000313|Ensembl:ENSRBIP00000038817.1};
OS Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Rhinopithecus.
OX NCBI_TaxID=61621 {ECO:0000313|Ensembl:ENSRBIP00000038817.1, ECO:0000313|Proteomes:UP000233180};
RN [1] {ECO:0000313|Ensembl:ENSRBIP00000038817.1, ECO:0000313|Proteomes:UP000233180}
RP NUCLEOTIDE SEQUENCE.
RA Wu, C.-I. and Zhang, Y.;
RT "Genome of Rhinopithecus bieti.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSRBIP00000038817.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR AlphaFoldDB; A0A2K6MSU0; -.
DR STRING; 61621.ENSRBIP00000038817; -.
DR Ensembl; ENSRBIT00000062836.1; ENSRBIP00000038817.1; ENSRBIG00000042892.1.
DR GeneTree; ENSGT00940000158678; -.
DR Proteomes; UP000233180; Unplaced.
DR GO; GO:0030895; C:apolipoprotein B mRNA editing enzyme complex; IEA:Ensembl.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0140767; F:enzyme-substrate adaptor activity; IEA:Ensembl.
DR GO; GO:0003727; F:single-stranded RNA binding; IEA:Ensembl.
DR GO; GO:0016554; P:cytidine to uridine editing; IEA:Ensembl.
DR GO; GO:0016556; P:mRNA modification; IEA:Ensembl.
DR GO; GO:2000623; P:negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:Ensembl.
DR GO; GO:0050821; P:protein stabilization; IEA:Ensembl.
DR CDD; cd19900; DSRM_A1CF; 1.
DR CDD; cd12498; RRM3_ACF; 1.
DR Gene3D; 3.30.70.330; -; 3.
DR InterPro; IPR044461; A1CF_DSRM.
DR InterPro; IPR006535; HnRNP_R/Q_splicing_fac.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR NCBIfam; TIGR01648; hnRNP-R-Q; 1.
DR PANTHER; PTHR21245:SF8; APOBEC1 COMPLEMENTATION FACTOR; 1.
DR PANTHER; PTHR21245; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN; 1.
DR Pfam; PF14709; DND1_DSRM; 1.
DR Pfam; PF00076; RRM_1; 3.
DR SMART; SM00360; RRM; 3.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 2.
DR PROSITE; PS50102; RRM; 3.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000233180};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176}.
FT DOMAIN 58..106
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 108..189
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 202..274
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
SQ SEQUENCE 562 AA; 61512 MW; 5A722FD21B28C5F4 CRC64;
MESNHKSGDG LSGTQKEAAL RALVQRTGYS LVQENGQRKY GGPPPGWDAD ELIPLCEKMM
MDFNGNNRGY AFVTFSNKLE AKNAIKQLNN YEIRNGRLLG VCASVDNCRL FVGASQNQKR
EEILSEMKKV TEGVVDVIVY PSAADKTKNR GFAFVEYESH RAAAMARRKL LPGRIQLWGH
PIAVDWAEPE VEVDEDTMSS VKILYVRNLM LSTSEEMIEK EFNNIKPGAV ERVKKIRDYA
FVHFSNREDA VEAMKALNGK VLDGSPIEVT LAKPVDKDSY VRYTRGTGGR GTMLQGEYTY
SLGQVYDPTT TYLGAPVFYA PQAYAAIPSL HFPATKGHLS NRAIIRAPSI REIYMNVPVG
AAGVRGLGGR GYLAYTGLGR GYQAKGDKRE DKLYDILPGM ELTPMNPVTL KPQGIKLAPQ
CLCPQKNNWG QPPVYQLHSA IGQDQRQLFL YKITIPALAS QNPAIHPFTP PKLSAYVDEA
KTYAAEYTLQ TLGIPTDGGD AGTMATAATA FPGYAVPNAT APVSAAQLKQ AVTLGQDLAA
YTTYEVYPTF AVTARGDGYG AF
//
