ID A0A2K6MXL3_RHIBE Unreviewed; 383 AA.
AC A0A2K6MXL3;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Cytohesin 1 {ECO:0000313|Ensembl:ENSRBIP00000040510.1};
GN Name=CYTH1 {ECO:0000313|Ensembl:ENSRBIP00000040510.1};
OS Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Rhinopithecus.
OX NCBI_TaxID=61621 {ECO:0000313|Ensembl:ENSRBIP00000040510.1, ECO:0000313|Proteomes:UP000233180};
RN [1] {ECO:0000313|Ensembl:ENSRBIP00000040510.1, ECO:0000313|Proteomes:UP000233180}
RP NUCLEOTIDE SEQUENCE.
RA Wu, C.-I. and Zhang, Y.;
RT "Genome of Rhinopithecus bieti.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSRBIP00000040510.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A2K6MXL3; -.
DR Ensembl; ENSRBIT00000064543.1; ENSRBIP00000040510.1; ENSRBIG00000043659.1.
DR GeneTree; ENSGT00940000157519; -.
DR Proteomes; UP000233180; Unplaced.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR CDD; cd01252; PH_GRP1-like; 1.
DR CDD; cd00171; Sec7; 1.
DR Gene3D; 1.10.220.20; -; 1.
DR Gene3D; 1.10.1000.11; Arf Nucleotide-binding Site Opener,domain 2; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR023394; Sec7_C_sf.
DR InterPro; IPR000904; Sec7_dom.
DR InterPro; IPR035999; Sec7_dom_sf.
DR PANTHER; PTHR10663:SF340; CYTOHESIN-1; 1.
DR PANTHER; PTHR10663; GUANYL-NUCLEOTIDE EXCHANGE FACTOR; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF01369; Sec7; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00222; Sec7; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF48425; Sec7 domain; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50190; SEC7; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000233180}.
FT DOMAIN 17..228
FT /note="SEC7"
FT /evidence="ECO:0000259|PROSITE:PS50190"
FT DOMAIN 246..362
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT COILED 11..52
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 383 AA; 44586 MW; 6B547DC3F2E10669 CRC64;
CSDDKIPSDL TAEERQELEN IRRRKQELLA DIQRLKDEIA EVANEIENLG STEERKNMQR
NKQVGIQFLI ENGLLKNTCE DIAQFLYKGE GLNKTAIGDY LGERQDEFNI QVLHAFVELH
EFTDLNLVQA LRQFLWSFRL PGEAQKIDRM MEAFAQRYCQ CNNGVFQSTD TCYVLSFAII
MLNTSLHNPN VKDKPTVERF IAMNRGINDG GDLPEELLRN LYESIKNEPF KIPEDDGNDL
THTFFNPDRE GWLLKLGGRV KTWKRRWFIL TDNCLYYFEY TTDKEPRGII PLENLSIREV
EDSKKPNCFE LYIPDNKDQV IKACKTEADG RVVEGNHTVY RISAPTPEEK EEWIKCIKAA
ISRDPFYEML AARKKKVSST KRH
//
