ID A0A2K6N3C3_RHIBE Unreviewed; 522 AA.
AC A0A2K6N3C3;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Delta/notch like EGF repeat containing {ECO:0000313|Ensembl:ENSRBIP00000042539.1};
GN Name=DNER {ECO:0000313|Ensembl:ENSRBIP00000042539.1};
OS Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Rhinopithecus.
OX NCBI_TaxID=61621 {ECO:0000313|Ensembl:ENSRBIP00000042539.1, ECO:0000313|Proteomes:UP000233180};
RN [1] {ECO:0000313|Ensembl:ENSRBIP00000042539.1, ECO:0000313|Proteomes:UP000233180}
RP NUCLEOTIDE SEQUENCE.
RA Wu, C.-I. and Zhang, Y.;
RT "Genome of Rhinopithecus bieti.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSRBIP00000042539.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR AlphaFoldDB; A0A2K6N3C3; -.
DR STRING; 61621.ENSRBIP00000042539; -.
DR Ensembl; ENSRBIT00000066582.1; ENSRBIP00000042539.1; ENSRBIG00000044529.1.
DR GeneTree; ENSGT00940000158872; -.
DR OMA; CECEDAY; -.
DR Proteomes; UP000233180; Unplaced.
DR GO; GO:0030425; C:dendrite; IEA:Ensembl.
DR GO; GO:0005769; C:early endosome; IEA:Ensembl.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0007417; P:central nervous system development; IEA:Ensembl.
DR CDD; cd00054; EGF_CA; 4.
DR Gene3D; 2.10.25.10; Laminin; 5.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR013032; EGF-like_CS.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR PANTHER; PTHR24049; CRUMBS FAMILY MEMBER; 1.
DR PANTHER; PTHR24049:SF22; DROSOPHILA CRUMBS HOMOLOG; 1.
DR Pfam; PF00008; EGF; 4.
DR Pfam; PF12661; hEGF; 2.
DR SMART; SM00181; EGF; 7.
DR SMART; SM00179; EGF_CA; 6.
DR SUPFAM; SSF57196; EGF/Laminin; 4.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR PROSITE; PS00010; ASX_HYDROXYL; 1.
DR PROSITE; PS00022; EGF_1; 5.
DR PROSITE; PS01186; EGF_2; 4.
DR PROSITE; PS50026; EGF_3; 7.
DR PROSITE; PS01187; EGF_CA; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000233180};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 7..46
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 222..261
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 262..303
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 305..341
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 343..379
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 381..417
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 464..502
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 11..21
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 36..45
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 232..249
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 251..260
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 293..302
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 331..340
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 369..378
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 385..395
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 522 AA; 55791 MW; C80839ABC8494019 CRC64;
MVSFQLVADP CASNPCHHGN CSSSSSSSSD GYLCICNEGY EGPNCEQALP SLPATGWTES
MAPRQLQPVP PTQEPDKILP HSQATVTLPT WQPKTGQKVV EMKWDQVEVI PDIACGNASS
NSSAGGRLVT FEVPQNTSVK IRQDATASLI LLWKVTATGF QQCSLIDGRS VTPLQASGGL
VLLEEMLALG NNHFIGFVND SVTKSIVALR LTLVVKVSTC VPGESHTSDL ECSGKGKCTT
KPSEATFSCT CEEQYVGTFC EEYDACQRKP CQNNASCIDA NEKQDGNNFT CVCLPGYTGE
LCQSKIDYCI LDPCRNGATC ISSLNGFTCQ CPEGYFGSAC EEKVDPCASS PCQNNGTCYV
DGVHFTCSCS SGFTGPTCAQ LIDFCALSPC AHGTCRSVGT SYKCLCDPGG YSPEIPSVCA
ILSNEYPQLP SFLAGPEWVV NGMHLTAGLS LCPSGYHGLY CEEEYNECLS APCLNAATCR
DLVNGYECVC GGCSELRSRH CTPAWVTNPM GRYSVYLILV YL
//
