ID   A0A2K6N3Q3_RHIBE        Unreviewed;       580 AA.
AC   A0A2K6N3Q3;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   RecName: Full=Major facilitator superfamily domain-containing protein 4A {ECO:0000256|ARBA:ARBA00040840};
GN   Name=MFSD4A {ECO:0000313|Ensembl:ENSRBIP00000042674.1};
OS   Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Rhinopithecus.
OX   NCBI_TaxID=61621 {ECO:0000313|Ensembl:ENSRBIP00000042674.1, ECO:0000313|Proteomes:UP000233180};
RN   [1] {ECO:0000313|Ensembl:ENSRBIP00000042674.1, ECO:0000313|Proteomes:UP000233180}
RP   NUCLEOTIDE SEQUENCE.
RA   Wu, C.-I. and Zhang, Y.;
RT   "Genome of Rhinopithecus bieti.";
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSRBIP00000042674.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC       {ECO:0000256|ARBA:ARBA00008335}.
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DR   AlphaFoldDB; A0A2K6N3Q3; -.
DR   Ensembl; ENSRBIT00000066717.1; ENSRBIP00000042674.1; ENSRBIG00000044581.1.
DR   GeneTree; ENSGT00530000063320; -.
DR   Proteomes; UP000233180; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   CDD; cd17453; MFS_MFSD4A; 1.
DR   Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   PANTHER; PTHR23121:SF10; MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 4A; 1.
DR   PANTHER; PTHR23121; SODIUM-DEPENDENT GLUCOSE TRANSPORTER 1; 1.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233180};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        21..40
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        52..74
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        81..101
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        107..126
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        138..160
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        221..241
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        307..335
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        347..365
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        377..396
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        402..424
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        436..458
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        464..487
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   580 AA;  63804 MW;  3DCE0BDD93A8BFA3 CRC64;
     MGCDGRVSGL LRRNLQPTLT YWSVFFSFGL CIAFLGPTLL DLRCQTHSSL PQISWVFFSQ
     QLCLLLGSAL GGVFKRTLAQ SLWALFTSSL AISLVFAVIP FCHDVKVLAS VMALAGLAMG
     CIDTVANMQL VRMYQKDSAV FLQVLHFFVG FGALLSPLIA DPFLSEANCL PANSTANTTS
     RGHLFHVSRV LAQHHVEAKP WSNQTFPELT PKDGAGTRVS YAFWIMALIN LPVPMAVLML
     LSKERLLTCC PQRRPLLLSA DELALETQPP EKEDASSLPP KFQSHPGHED LFSCCQRKNL
     RGAPYSFFAI HITAALVLFM TDGLTGAYSA FVYSYAVEKP LSVGHKVAGY LPSLFWGFIT
     LGRLLSIPIS SRMKPATMVF INVVGVVVTF LVLLIFSYNV VFLFVGTASL GLFLSSTFPS
     MLAYTEDSLQ YKGCATTVLV TGAGVGEMVL QMLVGSIFQA QGSYSFLVCG VIFGCLAFTF
     YILLLFFHRM HPGLPSVPTQ DRSIAMENSE CYQRDSICKD SPLISNLYVI IKTWIEEKSF
     SILSFRISLF RPQFLDFGII GFGGQIILCC GKLSCTLQFV
//