ID A0A2K6N556_RHIBE Unreviewed; 845 AA.
AC A0A2K6N556;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Adhesion G protein-coupled receptor G2 {ECO:0000313|Ensembl:ENSRBIP00000043163.1};
GN Name=ADGRG2 {ECO:0000313|Ensembl:ENSRBIP00000043163.1};
OS Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Rhinopithecus.
OX NCBI_TaxID=61621 {ECO:0000313|Ensembl:ENSRBIP00000043163.1, ECO:0000313|Proteomes:UP000233180};
RN [1] {ECO:0000313|Ensembl:ENSRBIP00000043163.1, ECO:0000313|Proteomes:UP000233180}
RP NUCLEOTIDE SEQUENCE.
RA Wu, C.-I. and Zhang, Y.;
RT "Genome of Rhinopithecus bieti.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSRBIP00000043163.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A2K6N556; -.
DR Ensembl; ENSRBIT00000067206.1; ENSRBIP00000043163.1; ENSRBIG00000044766.1.
DR GeneTree; ENSGT00940000156341; -.
DR OMA; RIWLFGN; -.
DR Proteomes; UP000233180; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.
DR Gene3D; 2.60.220.50; -; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR046338; GAIN_dom_sf.
DR InterPro; IPR017981; GPCR_2-like_7TM.
DR InterPro; IPR000832; GPCR_2_secretin-like.
DR InterPro; IPR017983; GPCR_2_secretin-like_CS.
DR InterPro; IPR000203; GPS.
DR PANTHER; PTHR12011; ADHESION G-PROTEIN COUPLED RECEPTOR; 1.
DR PANTHER; PTHR12011:SF264; ADHESION G-PROTEIN COUPLED RECEPTOR G2; 1.
DR Pfam; PF00002; 7tm_2; 1.
DR Pfam; PF01825; GPS; 1.
DR PRINTS; PR00249; GPCRSECRETIN.
DR SMART; SM00303; GPS; 1.
DR PROSITE; PS00650; G_PROTEIN_RECEP_F2_2; 1.
DR PROSITE; PS50261; G_PROTEIN_RECEP_F2_4; 1.
DR PROSITE; PS50221; GPS; 1.
PE 4: Predicted;
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000233180};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transducer {ECO:0000256|ARBA:ARBA00023040};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 482..505
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 517..540
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 552..575
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 587..608
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 636..658
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 679..707
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 480..711
FT /note="G-protein coupled receptors family 2 profile 2"
FT /evidence="ECO:0000259|PROSITE:PS50261"
FT REGION 746..766
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 845 AA; 93299 MW; 67B96B49147FEF27 CRC64;
MVFSGRQYGR VGRTEEVLLT FKIFLVIICL HVVLVTSLEG NVSVETTSLN GKNFSENQHI
TNGTLTGVLS LSELKRSELN KTLQTLSETY FIMCATAEAQ STLNCTFTIK LNNTMNACAV
IAALERVKIR PMEHCCCSVR TPCPSSPEEL EKLQCDLQDP IVCLADHPRG PPFSSSQSIP
VVPRATVLSQ VPSATSFAEP PDYSPVTHNV LSPIGEIHPL SPQPSAPIAS SPAIDMPPQS
EMISSPMPQT HVSGTPPPVK ASFSSPTVSA PANVITTSAP PVQTGKCKMP LEQQILQLLL
HQPNRCVFHL IILAPDIYSY LPLDFQVSLE TQAPENSIGT ITLPSSLMNN LPANDMELAS
RVQFNFFETP ALFQDPSLEN LSLISYVISS SVANLTVRNL TRNVTVTLKH VNPSQDKLTV
RCVFWDLGRN GGRGGWSDDG CSVKDRRLNE TICTCSHLTS FGILLDLSRT SVLPAQTMAL
TFITYIGCGL SSIFLSVTLV TYVAFEKIRR DYPSKILIQL CAALLLLNLV FLLDSWIALY
KMQGVCISVA VFLHYFLLVS FTWMGLEAFH MYLALVKVFN TYIRKYILKF CIVGWGVPAV
VVTIILTISP DNYGLGSYGK FPNGSPDDFC WINNNAVFYI TVVGYFCVIF SCSLWSWFSS
VELKEEATGS PAKTSIQDLR SIAVNVTFMY LFAIFNTLQG FFIFIFYCVA KENVRKQWRR
YLCCGELRLA ENSDWSKTAT NGLKKQTVNQ GVSSSSNSLQ SNSNSTNSTT LLVNNDCSVH
ASRNGNASTE RNGVSFSVQN GDVCLHDFTG KQHMFNEKED SCNGKGRMAL RRTSKRGSLH
FIEQM
//
