ID   A0A2K6N5L9_RHIBE        Unreviewed;      1432 AA.
AC   A0A2K6N5L9;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   SubName: Full=Talin 2 {ECO:0000313|Ensembl:ENSRBIP00000043320.1};
GN   Name=TLN2 {ECO:0000313|Ensembl:ENSRBIP00000043320.1};
OS   Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Rhinopithecus.
OX   NCBI_TaxID=61621 {ECO:0000313|Ensembl:ENSRBIP00000043320.1, ECO:0000313|Proteomes:UP000233180};
RN   [1] {ECO:0000313|Ensembl:ENSRBIP00000043320.1, ECO:0000313|Proteomes:UP000233180}
RP   NUCLEOTIDE SEQUENCE.
RA   Wu, C.-I. and Zhang, Y.;
RT   "Genome of Rhinopithecus bieti.";
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSRBIP00000043320.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   Ensembl; ENSRBIT00000067368.1; ENSRBIP00000043320.1; ENSRBIG00000044822.1.
DR   GeneTree; ENSGT00940000154699; -.
DR   Proteomes; UP000233180; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   CDD; cd12150; talin-RS; 1.
DR   Gene3D; 1.20.120.230; Alpha-catenin/vinculin-like; 2.
DR   Gene3D; 1.20.1410.10; I/LWEQ domain; 1.
DR   Gene3D; 1.20.1420.10; Talin, central domain; 6.
DR   InterPro; IPR036723; Alpha-catenin/vinculin-like_sf.
DR   InterPro; IPR035964; I/LWEQ_dom_sf.
DR   InterPro; IPR002558; ILWEQ_dom.
DR   InterPro; IPR037438; Talin1/2-RS.
DR   InterPro; IPR015009; Vinculin-bd_dom.
DR   PANTHER; PTHR19981; TALIN; 1.
DR   PANTHER; PTHR19981:SF34; TALIN-2; 1.
DR   Pfam; PF01608; I_LWEQ; 1.
DR   Pfam; PF08913; VBS; 1.
DR   SMART; SM00307; ILWEQ; 1.
DR   SUPFAM; SSF47220; alpha-catenin/vinculin-like; 5.
DR   SUPFAM; SSF109885; I/LWEQ domain; 2.
DR   PROSITE; PS50945; I_LWEQ; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233180}.
FT   DOMAIN          1184..1423
FT                   /note="I/LWEQ"
FT                   /evidence="ECO:0000259|PROSITE:PS50945"
FT   COILED          1391..1418
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   1432 AA;  151131 MW;  53C246564B3BE68F CRC64;
     TTQLISLNYI WRFSEQQHPS ILWVAARETA QALKTLAQAA RGVAASTTDP AAAHAMLDSA
     RDVMEGSAML IQEAKQALIA PGDAESQQRL AQVAKAVSHS LNNCVNCLPG QKDVDVALKS
     IGESSKKLLV DSLPPSTKPF QEAQSELNQA AADLNQSAGE VVHATRGQSG ELAAASGKFS
     DDFDEFLDAG IEMAGQAQTK EDQIQVIGNL KNISMASSKL LLAAKSLSVD PGAPNAKNLL
     AAAARAVTES INQLITLCTQ QAPGQKECDN ALRELETVKG MLDNPNEPVS DLSYFDCIES
     VMENSKVLGE SMAGISQNAK TGDLPAFGEC VGIASKALCG LTEAAAQAAY LVGISDPNSQ
     AGHQGLVDPI QFARANQAIQ MACQNLVDPG SSPSQVLSAA TIVAKHTSAL CNACRIASSK
     TANPVAKRHF VQSAKEVANS TANLVKTIKA LDGDFSEDNR SKCRMATAPL IEAVENLTAF
     ASNPEFVSIP AQISSEGSQA QEPILVSAKT MLESSSYLIR TARSLAINPK DPPTWSVLAG
     HSHTVSDSIK SLITSIRDKA PGQRECDYSI DGINRCIRDI EQASLAAVSQ SLATRDDISV
     EALQEQLTSV VQEIGHLIDP IATAARGEAA QLGHKVTQLA SYFEPLILAA VGVASKILDH
     QQQMTVLDQT KTLAESALQM LYAAKEGGGN PKAQHTHDAI TEAAQLMKEA VDDIMVTLNE
     AASEVGLVGG MVDAIAEAMS KLDEGTPPEP KGTFVDYQTT VVKYSKAIAV TAQEMMTKSV
     TNPEELGGLA SQMTSDYGHL AFQGQMAAAT AEPEEIGFQI RTRVQDLGHG CIFLVQKAGA
     LQVCPTDSYT KRELIECARA VTEKVSLVLS ALQAGNKGTQ ACITAATAVS GIIADLDTTI
     MFATAGTLNA ENSETFADHR ENILKTAKAL VEDTKLLVSG AASTPDKLAQ AAQSSAATIT
     QLAEVVKLGA ASLGSDDPET QVVLINAIKD VAKALSDLIS ATKGAASKPA DDPSMYQLKG
     AAKVMVTNVT SLLKTVKAVE DEATRGTRAL EATIECIKQE LTLFQSKDVP EKTSSPEESI
     RMTKGITMAT TKAVAAGNSC RQEDVIATAN LSRKAVSDML TACKQASFHP DVSDEVRTRA
     LRFGTECTLG YLDLLEHVLV VRKPISPLLP CYQESLSFGL ILGTEWVDPE DPTVIAETEL
     LGAAASIEAA AKKLEQLKPR AKPKQADETL DFEEQILEAA KSIAAATSAL VKSASAAQRE
     LVAQGKVGSI PANAADDGQW SQGLISAARM VAAATSSLCE AANASVQGHA SEEKLISSAK
     QVAASTAQLL VACKVKADQD SEAMRRLQAA GNAVKRASDN LVRAAQKAAF GKADDDDVVV
     KTKFVGGIAQ IIAAQEEMLK KERELEEARK KLAQIRQQQY KFLPTELRED EG
//