ID   A0A2K6N625_RHIBE        Unreviewed;      1386 AA.
AC   A0A2K6N625;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   SubName: Full=Cleavage and polyadenylation specific factor 1 {ECO:0000313|Ensembl:ENSRBIP00000043489.1};
GN   Name=CPSF1 {ECO:0000313|Ensembl:ENSRBIP00000043489.1};
OS   Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Rhinopithecus.
OX   NCBI_TaxID=61621 {ECO:0000313|Ensembl:ENSRBIP00000043489.1, ECO:0000313|Proteomes:UP000233180};
RN   [1] {ECO:0000313|Ensembl:ENSRBIP00000043489.1, ECO:0000313|Proteomes:UP000233180}
RP   NUCLEOTIDE SEQUENCE.
RA   Wu, C.-I. and Zhang, Y.;
RT   "Genome of Rhinopithecus bieti.";
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSRBIP00000043489.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the CPSF1 family.
CC       {ECO:0000256|ARBA:ARBA00038446}.
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DR   Ensembl; ENSRBIT00000067538.1; ENSRBIP00000043489.1; ENSRBIG00000044907.1.
DR   GeneTree; ENSGT00950000183151; -.
DR   Proteomes; UP000233180; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   Gene3D; 1.10.150.910; -; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 3.
DR   InterPro; IPR004871; Cleavage/polyA-sp_fac_asu_C.
DR   InterPro; IPR018846; Cleavage/polyA-sp_fac_asu_N.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   PANTHER; PTHR10644:SF2; CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 1; 1.
DR   PANTHER; PTHR10644; DNA REPAIR/RNA PROCESSING CPSF FAMILY; 1.
DR   Pfam; PF03178; CPSF_A; 1.
DR   Pfam; PF10433; MMS1_N; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000233180}.
FT   DOMAIN          92..664
FT                   /note="Cleavage/polyadenylation specificity factor A
FT                   subunit N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF10433"
FT   DOMAIN          1134..1351
FT                   /note="Cleavage/polyadenylation specificity factor A
FT                   subunit C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF03178"
FT   REGION          404..434
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          539..565
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          713..771
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          895..916
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        408..427
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        895..912
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1386 AA;  154786 MW;  B7D6C7D6E4B643EC CRC64;
     MYAVYKQAHP PTGLEFAMYC NFFNNSERNL VVAGTSQLYV YRLNRDAEAL TKNDRSTEGK
     AHREKLELAA SFSFFGNVMS MASVQLAGAK RDALLLSFKD AKLSVVEYDP GTHDLKTLSL
     HYFEEPELRD GFVQNVHTPR VRVDPDGRCA AMLVYGTRLV VLPFRRESLA EEHEGLVGEG
     QRSSFLPSYI IDVRALDEKL LNIIDLQFLH GYYEPTLLIL FEPNQTWPGR VAVRQDTCSI
     VAISLNITQK VHPVIWSLTS LPFDCTQALA VPKPIGGVVV FAVNSLLYLN QSVPPYGVAL
     NSLTTGTTAF PLRTQEGVRI TLDCAQATFI SYDKMVISLK GGEIYVLTLI TDGMRSVRAF
     HFDKAAASVL TTSMVTMEPG YLFLGSRLGN SLLLKYTEKL QEPPASAVRE AADKEEPPSK
     KKRVDATTTG GKSVPQDEVD EIEVYGSEAQ SGTQLATYSF EVCDSILNIG PCANAAMGEP
     AFLSEENSPE PDLEIVVCSG HGKNGALSVL QKSIRPQVVT TFELPGCYDM WTVIAPVRKE
     EEDNPKGEVT EQEPRSPEAD DDGRRHGFLI LSREDSTMIL QTGQEIMELD TSGFATQGPT
     VFAGNIGDNR YIVQVSPLGI RLLEGVNQLH FIPVDLGAPI VQCAVADPYV VIMSAEGHVT
     MFLLKSDSYG GRHHRLALHK PPLHHQSKVI TLCLYRDLSG MFTTESRLGG ARDELGGRIG
     SEAEGLGSET SPTVDDEEEM LYGDSGSLFS PSKEEARRSS QPPADRDPAP FRAEPTHWCL
     LVRENGTMEI YQLPDWRLVF LVKNFPVGQR VLVDSSFGQP TTQGEARREE ATRQGELPLV
     KEVLLVALGS RQSRPYLLVH VDQELLIYEA FPHDSQLGQG NLKVRFKKVP HNINFREKKP
     KPSKKKAEGG GTEEGAGARG RVARFRYFED IYGYSGVFIC GPSPHWLLVT GRGALRLHPM
     AIDGPVDSFA PFHNVNCPRG FLYFNRQGEL RISVLPAYLS YDAPWPVRKI PLRCTAHYVA
     YHVESKVYAV ATSTNTPCAR IPRMTGEEKE FETIERDERY IHPQQEAFSI QLISPVSWEA
     IPNARIELQE WEHVTCMKTV SLRSEETVSG LKGYVAAGTC LMQGEEVTCR GRIFLWSLRA
     SELTGMAFID TQLYIHQMIS VKNFILAADV MKSISLLRYQ EESKTLSLVS RDAKPLEVYS
     VDFMVDNAQL GFLVSDRDRN LMVYMYLPEA KESFGGMRLL RRADFHVGAH VNTFWRTPCR
     GATEGLSKKS VVWENKHITW FATLDGGIGL LLPMQEKTYR RLLMLQNALT TMLPHHAGLN
     PRAFRMLHVD RRTLQNAVRN VLDGELLNRY LYLSTMERSE LAKKIGTTPD IILDDLLETD
     RVTAHF
//