ID A0A2K6NAB8_RHIRO Unreviewed; 141 AA.
AC A0A2K6NAB8;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Keratin associated protein 4-4 {ECO:0000313|Ensembl:ENSRROP00000001217.1};
GN Name=KRTAP4-4 {ECO:0000313|Ensembl:ENSRROP00000001217.1};
OS Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Rhinopithecus.
OX NCBI_TaxID=61622 {ECO:0000313|Ensembl:ENSRROP00000001217.1, ECO:0000313|Proteomes:UP000233200};
RN [1] {ECO:0000313|Ensembl:ENSRROP00000001217.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- FUNCTION: In the hair cortex, hair keratin intermediate filaments are
CC embedded in an interfilamentous matrix, consisting of hair keratin-
CC associated proteins (KRTAP), which are essential for the formation of a
CC rigid and resistant hair shaft through their extensive disulfide bond
CC cross-linking with abundant cysteine residues of hair keratins. The
CC matrix proteins include the high-sulfur and high-glycine-tyrosine
CC keratins. {ECO:0000256|ARBA:ARBA00003327}.
CC -!- SUBUNIT: Interacts with hair keratins. {ECO:0000256|ARBA:ARBA00011662}.
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DR AlphaFoldDB; A0A2K6NAB8; -.
DR Ensembl; ENSRROT00000005353.1; ENSRROP00000001217.1; ENSRROG00000004858.1.
DR GeneTree; ENSGT00940000163975; -.
DR OMA; ITTCCSP; -.
DR Proteomes; UP000233200; Unplaced.
DR GO; GO:0005829; C:cytosol; IEA:UniProt.
DR GO; GO:0045095; C:keratin filament; IEA:InterPro.
DR InterPro; IPR002494; KAP.
DR PANTHER; PTHR23262; KERATIN ASSOCIATED PROTEIN; 1.
DR PANTHER; PTHR23262:SF208; KERATIN-ASSOCIATED PROTEIN 4-1; 1.
DR Pfam; PF13885; Keratin_B2_2; 2.
PE 4: Predicted;
KW Keratin {ECO:0000256|ARBA:ARBA00022744};
KW Reference proteome {ECO:0000313|Proteomes:UP000233200};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
SQ SEQUENCE 141 AA; 15213 MW; 7636852B0B46A752 CRC64;
MVNSCCGSVC SDQGCGLENC CRPSCCHPTC CRTTCCRPSC CQTTCCRTTC CRPSCCVSSC
CRPQCCQTTC CRTTCCRPSC CRPQCCQSVC CQPTCCRPSY CVSSCCRPQC CQTTCCRTTC
CRPSCCVSSC YRSPCGQSLC C
//