ID   A0A2K6NDM2_RHIRO        Unreviewed;       980 AA.
AC   A0A2K6NDM2;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Ankyrin 3 {ECO:0000313|Ensembl:ENSRROP00000002374.1};
GN   Name=ANK3 {ECO:0000313|Ensembl:ENSRROP00000002374.1};
OS   Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Rhinopithecus.
OX   NCBI_TaxID=61622 {ECO:0000313|Ensembl:ENSRROP00000002374.1, ECO:0000313|Proteomes:UP000233200};
RN   [1] {ECO:0000313|Ensembl:ENSRROP00000002374.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004370}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A2K6NDM2; -.
DR   Ensembl; ENSRROT00000010694.1; ENSRROP00000002374.1; ENSRROG00000007163.1.
DR   GeneTree; ENSGT00940000154939; -.
DR   Proteomes; UP000233200; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd08803; Death_ank3; 1.
DR   Gene3D; 2.60.220.30; -; 2.
DR   Gene3D; 2.60.40.2660; -; 1.
DR   Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR   InterPro; IPR037971; Ank3_Death.
DR   InterPro; IPR040745; Ankyrin_UPA.
DR   InterPro; IPR011029; DEATH-like_dom_sf.
DR   InterPro; IPR000488; Death_domain.
DR   InterPro; IPR000906; ZU5_dom.
DR   PANTHER; PTHR24198; ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR24198:SF173; ANKYRIN-3; 1.
DR   Pfam; PF00531; Death; 1.
DR   Pfam; PF17809; UPA_2; 1.
DR   Pfam; PF00791; ZU5; 1.
DR   SMART; SM00005; DEATH; 1.
DR   SMART; SM00218; ZU5; 1.
DR   SUPFAM; SSF47986; DEATH domain; 1.
DR   PROSITE; PS50017; DEATH_DOMAIN; 1.
DR   PROSITE; PS51145; ZU5; 2.
PE   4: Predicted;
KW   ANK repeat {ECO:0000256|ARBA:ARBA00023043};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233200};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          118..273
FT                   /note="ZU5"
FT                   /evidence="ECO:0000259|PROSITE:PS51145"
FT   DOMAIN          275..422
FT                   /note="ZU5"
FT                   /evidence="ECO:0000259|PROSITE:PS51145"
FT   DOMAIN          611..695
FT                   /note="Death"
FT                   /evidence="ECO:0000259|PROSITE:PS50017"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          758..799
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          929..980
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        758..772
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        943..957
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   980 AA;  108825 MW;  248F8E22B1C6BBA7 CRC64;
     MALPQSEDAM TGDTDKYLGP QDLKELGDDS LPAEGYMGFS LGARSASLRS FSSDRSYTLN
     RSSYARDSMM IEELLVPSKE QHLTFTREFD SDSLRHYSWA ADTLDNVNLV SSPIHSGFLV
     SFMVDARGGS MRGSRHHGMR IIIPPRKCTA PTRITCRLVK RHKLANPPPM VEGEGLASRL
     VEMGPAGAQF LGPVIVEIPH FGSMRGKERE LIVLRSENGE TWKEHQFDSK NEDLTELLNG
     MDEELDSPEE LGKKRICRII TKDFPQYFAV VSRIKQESNQ IGPEGGILSS TTVPLVQASF
     PEGALTKRIR VGLQAQPVPD EIVKKILGNK ATFSPIVTVE PRRRKFHKPI TMTIPVPPPS
     GEGVSNGYKG DSTPNLRLLC SITGGTSPAQ WEDITGTTPL TFIKDCVSFT TNVSARFWLA
     DCHQVLETVG LATQLYRELI CVPYMAKFVV FAKMNDPVES SLRCFCMTDD KVDKTLEQQE
     NFEEVARSKD IEVLEGKPIY VDCYGNLAPL TKGGQQLVFN FYAFKENRLP FSIKIRDTSQ
     EPCGRLSFLK EPKTTKGLPQ TAVCNLNITL PAHKKIEKTD RRQSFASLAL RKRYSYLTEP
     GMSPQSPCER TDIRMAIVAD HLGLSWTELA RELNFSVDEI NQIRVENPNS LISQSFMLLK
     KWVTRDGKNA TTDALTSVLT KINRIDIVTL LEGPIFDYGN ISGTRSFADE NNVFHDPVDG
     YPSLQVELET PTGLHYTPPT PFQQDDYFSD ISSIESPLRT PSRLSDGLVP SQGNIEHSAD
     GPPVVTAEDT SLEDSKLEDS VPLTEMPEAV DVDESQLENV CLSEYPQYLG NLAGPDQCRD
     SITSYLKGEA GKFEANGSHT EITPEAKTKS YFPESQNDVG KQSTKETLKP KIHGSGHVEE
     PASPLAAYQK SLEETSKLII EDTKPCVPVS MKKMSRTSPA DGKPRLNLHE EEGSSGSEQK
     VSCKNNNQKE KKSHVAWYSV
//