GenomeNet

Database: UniProt
Entry: A0A2K6NE80_RHIRO
LinkDB: A0A2K6NE80_RHIRO
Original site: A0A2K6NE80_RHIRO 
ID   A0A2K6NE80_RHIRO        Unreviewed;      3071 AA.
AC   A0A2K6NE80;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   10-FEB-2021, entry version 19.
DE   SubName: Full=Centromere protein F {ECO:0000313|Ensembl:ENSRROP00000002587};
GN   Name=CENPF {ECO:0000313|Ensembl:ENSRROP00000002587};
OS   Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Rhinopithecus.
OX   NCBI_TaxID=61622 {ECO:0000313|Ensembl:ENSRROP00000002587, ECO:0000313|Proteomes:UP000233200};
RN   [1] {ECO:0000313|Ensembl:ENSRROP00000002587}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=25362486;
RA   Zhou X., Wang B., Pan Q., Zhang J., Kumar S., Sun X., Liu Z., Pan H.,
RA   Lin Y., Liu G., Zhan W., Li M., Ren B., Ma X., Ruan H., Cheng C., Wang D.,
RA   Shi F., Hui Y., Tao Y., Zhang C., Zhu P., Xiang Z., Jiang W., Chang J.,
RA   Wang H., Cao Z., Jiang Z., Li B., Yang G., Roos C., Garber P.A.,
RA   Bruford M.W., Li R., Li M.;
RT   "Whole-genome sequencing of the snub-nosed monkey provides insights into
RT   folivory and evolutionary history.";
RL   Nat. Genet. 46:1303-1310(2014).
RN   [2] {ECO:0000313|Ensembl:ENSRROP00000002587}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2018) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   RefSeq; XP_010371258.1; XM_010372956.1.
DR   Ensembl; ENSRROT00000011590; ENSRROP00000002587; ENSRROG00000010374.
DR   GeneTree; ENSGT00730000111187; -.
DR   OMA; YNAQLVQ; -.
DR   OrthoDB; 205405at2759; -.
DR   Proteomes; UP000233200; Unplaced.
DR   GO; GO:0097539; C:ciliary transition fiber; IEA:Ensembl.
DR   GO; GO:0000940; C:condensed chromosome outer kinetochore; IEA:Ensembl.
DR   GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR   GO; GO:0030496; C:midbody; IEA:Ensembl.
DR   GO; GO:0005635; C:nuclear envelope; IEA:Ensembl.
DR   GO; GO:0016363; C:nuclear matrix; IEA:Ensembl.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   GO; GO:0000922; C:spindle pole; IEA:Ensembl.
DR   GO; GO:0070840; F:dynein complex binding; IEA:Ensembl.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0008022; F:protein C-terminus binding; IEA:Ensembl.
DR   GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl.
DR   GO; GO:0008134; F:transcription factor binding; IEA:Ensembl.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0051310; P:metaphase plate congression; IEA:Ensembl.
DR   GO; GO:0000278; P:mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0015031; P:protein transport; IEA:Ensembl.
DR   GO; GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0021591; P:ventricular system development; IEA:Ensembl.
DR   InterPro; IPR043513; Cenp-F.
DR   InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR   InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR   InterPro; IPR018463; Centromere_CenpF_N.
DR   PANTHER; PTHR18874; PTHR18874; 2.
DR   Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR   Pfam; PF10473; CENP-F_leu_zip; 3.
DR   Pfam; PF10481; CENP-F_N; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233200}.
FT   DOMAIN          1..307
FT                   /note="CENP-F_N"
FT                   /evidence="ECO:0000259|Pfam:PF10481"
FT   DOMAIN          1850..1992
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2088..2227
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2270..2409
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2927..2970
FT                   /note="CENP-F_C_Rb_bdg"
FT                   /evidence="ECO:0000259|Pfam:PF10490"
FT   REGION          208..234
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1626..1647
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1678..1701
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2846..3071
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          13..131
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          164..191
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          280..333
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          336..384
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          389..458
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          503..572
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          580..607
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          615..642
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          682..702
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          789..830
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          856..914
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          919..953
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          986..1077
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1082..1116
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1153..1201
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1243..1270
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1354..1374
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1506..1526
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1538..1569
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1581..1603
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1747..1774
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1782..1802
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1810..1830
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1868..1923
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1927..1954
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1959..2035
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2064..2091
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2099..2235
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2250..2273
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2281..2315
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2323..2424
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2432..2501
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2519..2560
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2575..2641
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2646..2673
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2696..2730
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2738..2782
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2793..2820
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        2885..2914
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2919..2941
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2956..2970
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2986..3037
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   3071 AA;  352731 MW;  B805E65D01090379 CRC64;
     MSWALEEWKE GLPTRALQKI QELEGQLDKL KKEKQQRQFQ LDSLEAALQK QKQKVENEKT
     EGTNLKRENQ RLMEICESLE KTKQKISHEL QVKESQVNFQ EGQLNSGKKQ IEKLEQELKR
     CKSELERSQQ AAQSADVSLN PCNTPQKIFT TPLTPSQYYS GSKYEDLKEK YNKEVEERKR
     LEAEVKALQA KKASQTLPQT TMNHRDIARH QASSSVFSWQ QEKTPSHLSS NSQKTPIRRD
     FSACYFSGEQ EVTPSRSALL IGKRDANNSF FDNSSSPHLL EQLKVQNQEL RSKINELELR
     LQGQEKEMKG QVNKFQELQL QLEKAKVESI EKEKVLNKCR DELVRTTAQY DQASTKCTAL
     EQKLKKLTED LSCQRQNAES ARCSLEQKIK EKEKEFQEVT AVKQQLEKNL EEFKQKLCRA
     EQASQASQIK EDELRRSVEE MKKENNLLKS QSEQKTREVC HLEAELKNVK QCLNQSQNFA
     EEMKVKNTSQ ETMLRDLHEK INQQENSLTL EKLKLAVAEL EKQRDCSQDL LKKREHHIEQ
     LNDKLSKTEK ESKALLSALE LKKKEYEELK EEKTLFSCWK SENEKLLTQM ESEKENLQSK
     INHLETCLKT QQIKSHEYNE RVRTLEMDRE NLSVEIRNLH NVIDSKSVEV ETQKLAYVEL
     QQKAEFSDQK HQKEIENMCL KTSQLTGQVE DLEHKLQLLS NEIMDKDRCY QDLHAEYESL
     RDLLKSRDAS LATNEDHQRS LLAFDEQPAM HNSFANIIEE QGSMPSERSE CRLEADQSPK
     NSAILQNRVD SLEFSLESQK QMNSDLQKQC EELVQIKGEI EENLRKAEQM HQSFVAETSQ
     RISKLQEDTS AHQNVVAETL SALENKEKEL QLLNDKLETE QAEIQELKQS NHLLEDSLKE
     LQLLSETLSL EKKEMSSIIS LNKREIEQLT QENETLKEIN ASLNQEKMNL IQKSESFANY
     IDEREKSISE LSDQYKQEKL ILLQRCEETG NAYEDLSQKY KAAQEKNSKL ECLLNECTSL
     CENRKNELEQ LKEAFAKEHQ EFLTKLAFAE ERNQNLMLEL ETVQQDLRSE MTDTQNNSKS
     GTDGLKQEIM TLKEEQNKMQ KEVNDVLQEN EQLMKVMKTK HECQNLESEP IRNSVKERES
     ERNQCNFKPQ MDLEVKEISL DSYNAQLVQL EAMLRNMELK LQESEKEKEC LQHELQIIRG
     DLETRNLQDM QSQEISGLKD CEVDAEERYI SVLHELSTSQ NDNAHLECSL QTAMNKLNEL
     EKICEILQAE KCELVTEPND SRSECITATR KMAEEVGKLV NEVKILNEDS GLLHGELVED
     VPGGEFGEQP NEQHPMCLAP LDESNSYEHL TLSNKEVQIH FAELQEKFSS LQSEHKILYD
     QHCQMSSKMS ELQTYIDSLK AENLVLSTNL RNFQGDLVKE MQPGLEEGLV PSLSSSCVPD
     SPSLSSLGDS SFYKALLEQT GEMSLLNNLE GTVSANQCSV DEVFCSSLEE ENLTKKETPS
     APVKGVEELE SLCEAYRQSL KKLEEKMESQ GIMKNKEIQE LEQLLSSERQ ELDCLRKQYL
     SENEQWQQKL TSVTLEMESK LAAEKKQTEQ LSLELEVARL QLQGLDLSSR SLLGIDTEDA
     IQGRNESCDI SKEHTSETTD RTPKHDVHQI CDKGVQQDLH LDIEKITETG AVKLTGQCSG
     EQYPDTSYET PGEDKTQGSS ECMSELSFSG ANASVPMDFL GNQENIQNLQ LRVKETSNEN
     LRLLHVIEER DRKVESLLNE MKELDSKLHL QEVQLMTKIE ACIELEKIVG ELKKENSDLS
     EKLEYFSCDN QELLQRVESS EGLNSNLEMR ADKSSHEDID DNVAKVNDSW KERFLDVENE
     LSRIRSVKAN IEHQALSLEA DLEIVQTEKL CLEKDNENKQ KVIVCLEEEL SVVTSERNQL
     RGELDTMSKK TMELDQLSEK MKEKTQELES HRSEYLHCIQ VAEAEVKEKT ELLQTLSSDV
     SELLKDKTHL QEKLQSLEKD SQALSLTKCE LENQIAQLNK EKELLVKESE SLQTRLNESD
     YEKLNISKAL EAALVEKGEF ALRLSSTQEE VHQLRRGIEK LRVRIEADER KQLHVAEKLK
     ERERENDSLK DKVENLEREL QMSEENQELV ILDAENSKAE VETLKTQIEE MARNLKVFEL
     DLVTLRSEKE NLTKQIQEKQ GQASELDKLL SSFKSLLEEK EQAEIQIKEE SKTAVEMLQN
     QLKELNEAVA ALCGDQETMK ATEQSLDPPV EEAHQLRNSI EKLRARLETD EKKQLCVLEQ
     LKESEHHADL LKSRVENLER ELEIAGKNQE HAALEAESSK GEVETLKAKI EGMTRSLREL
     ELDLATIRSE KENLTNKLQK EQERISELEI INSSFENILR EKEQEKVQMK EKSNTAMEML
     QTQLKELNER VTALHNDQEA CKAKEQNLSS QVDCLELEKA QLLQGLDEAK NNNIVLQSSV
     NGLIQEVEDG KQKLEKKDEE ISRLKNQIQD QEQLVFRLSQ VEGEHQLWKK QNLELGNLTV
     ELEQKIQVLQ SKNVSLQDTL EVLQSSYKNL ENELELTKMD KMSFVEKVNT MTAKETELQR
     EMHEIAQKTA ELQEELSGEK NRLTGELQLL LEEIKSSKDQ LKELTLENSE LKKSLDCMHK
     DQVEKEGKVR EEIAEYQLRL HETEKKHQAL LLETNKQYEI EIHTYREKLT SKEECLSSQK
     LEMDLLKSSK EELNNSLKAT TQVLEELKKT KMDNLKYVNQ LKKENERAQG KIKLLIKSCK
     QLEEEKEILQ KELSKLQAAQ EKQKIGTVVG TKVDELTTEI KELKEALEEK TKEADEYLDK
     YCSLLISHEK LEKAKEMLET QVAHLCSQQS KPDSRGSPLL DPVVPGPSPI LSAAEKRLSS
     GQKKASGKRQ RSSGMWENGR GPTPSTSETF SKKSKKAVMS GIHPAEDTEG TEFEPEGLPE
     VVKKGFADIP TGKTSPYILR RTTMATRTSP RLAAQKLALS PLSLGKENLA ESSKPTAGGS
     RSQKVKVAQQ SPVDSDTILR EPTTKSLPVN NLPARSPTDS PREGLRVKRG RLAPNPKAGL
     EPKGSENCKV Q
//
DBGET integrated database retrieval system