ID   A0A2K6NP81_RHIRO        Unreviewed;       313 AA.
AC   A0A2K6NP81;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Calcium homeostasis modulator family member 6 {ECO:0000313|Ensembl:ENSRROP00000006080.1};
GN   Name=CALHM6 {ECO:0000313|Ensembl:ENSRROP00000006080.1};
OS   Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Rhinopithecus.
OX   NCBI_TaxID=61622 {ECO:0000313|Ensembl:ENSRROP00000006080.1, ECO:0000313|Proteomes:UP000233200};
RN   [1] {ECO:0000313|Ensembl:ENSRROP00000006080.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the CALHM family.
CC       {ECO:0000256|ARBA:ARBA00008497}.
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DR   AlphaFoldDB; A0A2K6NP81; -.
DR   STRING; 61622.ENSRROP00000006080; -.
DR   Ensembl; ENSRROT00000027185.1; ENSRROP00000006080.1; ENSRROG00000024470.1.
DR   GeneTree; ENSGT01030000234610; -.
DR   OMA; AVVFQCP; -.
DR   Proteomes; UP000233200; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR029569; CALHM.
DR   PANTHER; PTHR32261; CALCIUM HOMEOSTASIS MODULATOR PROTEIN; 1.
DR   PANTHER; PTHR32261:SF4; CALCIUM HOMEOSTASIS MODULATOR PROTEIN 6; 1.
DR   Pfam; PF14798; Ca_hom_mod; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233200};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        45..68
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        100..122
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        174..197
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   313 AA;  34224 MW;  F588198A7EF4CB0F CRC64;
     MEKFQAVLDL HLKHHSALGY GLVTLLTAGG ERIFSAVVFQ CPCSAAWNLP LVFLLVPALA
     LFLLGYVLSA RTWRLITGCG CRARASCGSG LRGSLVCAQL SAAAALAPLT WVAVALLGGA
     FYECAASGSA VLAQRLCLHR DHNCAAELPL VPCHQAKASD VQDLLKDLKA QSQVLGWILI
     AAVIIILLIF TCVSRCLSPV SFLQLKFWKI YLEKEQQILK SKATEHATEL AKENVKCFFE
     GSHPKECNTP SVKEWQQISS LYTFNQKDQY YSMLHKYVNR KEKTHSIRST EGDTVIPVLG
     FVDSSGINST PGL
//