ID   A0A2K6NX27_RHIRO        Unreviewed;      1031 AA.
AC   A0A2K6NX27;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 30.
DE   SubName: Full=ST18 C2H2C-type zinc finger transcription factor {ECO:0000313|Ensembl:ENSRROP00000008838.1};
GN   Name=ST18 {ECO:0000313|Ensembl:ENSRROP00000008838.1};
OS   Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Rhinopithecus.
OX   NCBI_TaxID=61622 {ECO:0000313|Ensembl:ENSRROP00000008838.1, ECO:0000313|Proteomes:UP000233200};
RN   [1] {ECO:0000313|Ensembl:ENSRROP00000008838.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the MYT1 family.
CC       {ECO:0000256|ARBA:ARBA00010194}.
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DR   AlphaFoldDB; A0A2K6NX27; -.
DR   Ensembl; ENSRROT00000032919.1; ENSRROP00000008838.1; ENSRROG00000028859.1.
DR   GeneTree; ENSGT00940000159905; -.
DR   OMA; RYTCYQE; -.
DR   Proteomes; UP000233200; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   Gene3D; 4.10.320.30; -; 6.
DR   InterPro; IPR013681; Myelin_TF.
DR   InterPro; IPR002515; Znf_C2H2C.
DR   InterPro; IPR036060; Znf_C2H2C_sf.
DR   PANTHER; PTHR10816; MYELIN TRANSCRIPTION FACTOR 1-RELATED; 1.
DR   PANTHER; PTHR10816:SF9; SUPPRESSION OF TUMORIGENICITY 18 PROTEIN; 1.
DR   Pfam; PF08474; MYT1; 1.
DR   Pfam; PF01530; zf-C2HC; 6.
DR   SUPFAM; SSF103637; CCHHC domain; 6.
DR   PROSITE; PS51802; ZF_CCHHC; 6.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233200};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU01143}.
FT   SIGNAL          1..15
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           16..1031
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5014440010"
FT   DOMAIN          464..699
FT                   /note="Myelin transcription factor 1"
FT                   /evidence="ECO:0000259|Pfam:PF08474"
FT   REGION          42..74
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          156..205
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          235..277
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          506..547
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          656..694
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          910..972
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        50..74
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        166..196
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        261..277
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        531..547
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        658..683
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1031 AA;  113592 MW;  02A2F3DF8C810963 CRC64;
     RFTIFLIFLN HYSVAYDCSM AKKRRAEDPA LGVPVNKRKS LLMKPRHYSP NADCQEDRSD
     RTEDDGPLET HDHSTAEEVM IKPMDESLLS AAQENSSRKE DRYSCYQELV VKSLMHLGKF
     EKNVSVQTTS ENLNDSGIQS LKAESDETDE CFLIHSDDGR DKINDSQPPF CSSDDNESNS
     ESAENGWDSG SNFSEETKPP RVPKYVLTDH KKDLLEVPEI KTEGDKFIPC ENRCDSETER
     KDPQNAHAEP LDGNAQPSFP DVEEEDSKSL AVMTEESSDL EKAKGNLSLL EQAIALQAER
     GCVFHNTYKE LDRFLLEHLA GERRQTKVID MSGRQIFNNK HSPRPEKRET KCPIPGCDGT
     GHVTGLYPHH RSLSGCPHKV RVPLEILAMH ENVLKCPTPG CTGRGHVNSN RNTHRSLSGC
     PIAAAEKLAM SQDKNQLDSP QTGQCPDQAH RTSLVKQIEF NIPSQAITSP RATVSKEQEK
     FGKVPFDYAS FDAQVFGKRP LIQTVQGRKT PPFPESKHFS NPVKFPNRLP SAGAHTQSPG
     RASSYSYGQC SEDTHIAAAA AILNLSTRCR EATDILSNKP QSLHAKGAEI EVDENGTLDL
     SMKKNRILDK AAPLTSSNTS IPTPSSSPFK TSSILVNAAF YQALCDQEGW DTPINYSKTH
     GKTEEEKEKD PVSSLENLEE KKFPGEASIP SPKPKLHARD LKKELITCPT PGCDGSGHVT
     GNYASHRSVS GCPLADKTLK SLMAANSQEL KCPTPGCDGS GHVTGNYASH RSLSGCPRAR
     KGGVKMTPTK EEKEDPELKC PVIGCDGQGH ISGKYTSHRT ASGCPLAAKR QKENPLNGAS
     LSWKLNKQEL PHCPLPGCNG LGHVNNVFVT HRSLSGCPLN AQAIKKGKVS EELMTIKLKA
     TGGIESDEEI RHLDEEIKEL NESNLKIEAD MMKLQTQITS MESNLKTIEE ENKLIEQNNE
     SLLKELAGLS QALISSLADI QLPQMGPISE QNFEAYVNTL TDMYSNLERD YSPECKALLE
     SIKQAVKGIH V
//