ID A0A2K6NY34_RHIRO Unreviewed; 211 AA.
AC A0A2K6NY34;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Synaptosomal-associated protein {ECO:0000256|RuleBase:RU003496};
GN Name=SNAP23 {ECO:0000313|Ensembl:ENSRROP00000009192.1};
OS Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Rhinopithecus.
OX NCBI_TaxID=61622 {ECO:0000313|Ensembl:ENSRROP00000009192.1, ECO:0000313|Proteomes:UP000233200};
RN [1] {ECO:0000313|Ensembl:ENSRROP00000009192.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004193};
CC Lipid-anchor {ECO:0000256|ARBA:ARBA00004193}. Membrane
CC {ECO:0000256|ARBA:ARBA00004635}; Lipid-anchor
CC {ECO:0000256|ARBA:ARBA00004635}. Synapse, synaptosome
CC {ECO:0000256|ARBA:ARBA00034102}.
CC -!- SIMILARITY: Belongs to the SNAP-25 family.
CC {ECO:0000256|ARBA:ARBA00009480, ECO:0000256|RuleBase:RU003496}.
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DR RefSeq; XP_010365322.1; XM_010367020.1.
DR RefSeq; XP_010365323.1; XM_010367021.1.
DR AlphaFoldDB; A0A2K6NY34; -.
DR STRING; 61622.ENSRROP00000009192; -.
DR Ensembl; ENSRROT00000033275.1; ENSRROP00000009192.1; ENSRROG00000029021.1.
DR GeneID; 104665260; -.
DR KEGG; rro:104665260; -.
DR CTD; 8773; -.
DR GeneTree; ENSGT00950000182843; -.
DR OMA; DLTKCCG; -.
DR OrthoDB; 388796at2759; -.
DR Proteomes; UP000233200; Unplaced.
DR GO; GO:0005912; C:adherens junction; IEA:Ensembl.
DR GO; GO:0042582; C:azurophil granule; IEA:Ensembl.
DR GO; GO:0005739; C:mitochondrion; IEA:Ensembl.
DR GO; GO:0043005; C:neuron projection; IEA:UniProtKB-KW.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0031201; C:SNARE complex; IEA:Ensembl.
DR GO; GO:0042581; C:specific granule; IEA:Ensembl.
DR GO; GO:0045202; C:synapse; IEA:UniProtKB-SubCell.
DR GO; GO:0019905; F:syntaxin binding; IEA:Ensembl.
DR GO; GO:0002553; P:histamine secretion by mast cell; IEA:Ensembl.
DR CDD; cd15884; SNARE_SNAP23C; 1.
DR CDD; cd15895; SNARE_SNAP23N; 1.
DR Gene3D; 1.20.5.110; -; 2.
DR InterPro; IPR000928; SNAP-25_dom.
DR InterPro; IPR000727; T_SNARE_dom.
DR PANTHER; PTHR19305; SYNAPTOSOMAL ASSOCIATED PROTEIN; 1.
DR PANTHER; PTHR19305:SF4; SYNAPTOSOMAL-ASSOCIATED PROTEIN 23; 1.
DR Pfam; PF00835; SNAP-25; 1.
DR SMART; SM00397; t_SNARE; 2.
DR SUPFAM; SSF58038; SNARE fusion complex; 2.
DR PROSITE; PS50192; T_SNARE; 2.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000233200};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Synapse {ECO:0000256|ARBA:ARBA00023018};
KW Synaptosome {ECO:0000256|ARBA:ARBA00022599}.
FT DOMAIN 14..76
FT /note="T-SNARE coiled-coil homology"
FT /evidence="ECO:0000259|PROSITE:PS50192"
FT DOMAIN 146..208
FT /note="T-SNARE coiled-coil homology"
FT /evidence="ECO:0000259|PROSITE:PS50192"
FT REGION 116..137
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 45..79
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 116..135
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 211 AA; 23224 MW; 988B8CB6FF474537 CRC64;
MDNLSSEEIQ LRAHQITDES LESTRRILGL AIESQDAGIK TITMLDEQGE QLNRIEEGLD
QINKDMRETE KTLTELNKCC GLCVCPCNRT KNFESGKAYK TTWGDGGENS PCNVVSKQPG
PVTNGQPQQP TTGAASGGYI KRITNDARED EMEENLTQVG SILGNLKDMA LNIGNEIDAQ
NPQIKRITDK ADTNKDRIDI ANARAKKLID S
//
