ID A0A2K6P0K9_RHIRO Unreviewed; 1113 AA.
AC A0A2K6P0K9;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=RNA binding motif protein 6 {ECO:0000313|Ensembl:ENSRROP00000010061.1};
GN Name=RBM6 {ECO:0000313|Ensembl:ENSRROP00000010061.1};
OS Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Rhinopithecus.
OX NCBI_TaxID=61622 {ECO:0000313|Ensembl:ENSRROP00000010061.1, ECO:0000313|Proteomes:UP000233200};
RN [1] {ECO:0000313|Ensembl:ENSRROP00000010061.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A2K6P0K9; -.
DR Ensembl; ENSRROT00000034157.1; ENSRROP00000010061.1; ENSRROG00000029411.1.
DR GeneTree; ENSGT00940000157976; -.
DR OMA; REVGSCM; -.
DR Proteomes; UP000233200; Unplaced.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd12314; RRM1_RBM6; 1.
DR CDD; cd12563; RRM2_RBM6; 1.
DR Gene3D; 3.30.70.330; -; 2.
DR Gene3D; 2.160.20.80; E3 ubiquitin-protein ligase SopA; 1.
DR InterPro; IPR000467; G_patch_dom.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR041591; OCRE.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR034123; RBM6_RRM1.
DR InterPro; IPR034125; RBM6_RRM2.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR13948; RNA-BINDING PROTEIN; 1.
DR PANTHER; PTHR13948:SF22; RNA-BINDING PROTEIN 6; 1.
DR Pfam; PF01585; G-patch; 1.
DR Pfam; PF17780; OCRE; 1.
DR SMART; SM00443; G_patch; 1.
DR SMART; SM00360; RRM; 2.
DR SUPFAM; SSF141571; Pentapeptide repeat-like; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 2.
DR PROSITE; PS50174; G_PATCH; 1.
DR PROSITE; PS50102; RRM; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000233200};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}.
FT DOMAIN 446..526
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 1041..1087
FT /note="G-patch"
FT /evidence="ECO:0000259|PROSITE:PS50174"
FT REGION 1..381
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 403..444
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 564..644
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 731..777
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 817..937
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 994..1097
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 966..993
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 101..124
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 131..224
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 231..278
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 296..337
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 344..370
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 421..443
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 564..578
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 584..644
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 732..761
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 762..777
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 817..854
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 862..876
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 994..1042
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1113 AA; 127590 MW; 8B8D85515D1B70AB CRC64;
MWFANGSQEE RFAPGWNRDY PPPPLKSHAQ ERHSGNFPGR DSLPFDFQGH SGPPFANVEE
HSFSYGARDG PHGDYRGGEG PGHDFRGGDF SSSDFQSRDS SQLDFRGRDI HSGDFRDREG
PPMDYRGGDG TSMDYRGREA PHMNYRDRDA HAVDFRGRDA PPSDFRGRGT YDLDFRGRDG
SHADFRGRDL SDLDFRAREQ SRSDFRNRDV SDLDFRDKDG TQVDFRGRGS GTTDLDFRDR
DTPHSDFRGR HRSRTDQDFR GREMGTCMEF KDREMPPVDP NILDYIQPST QDREHSGMNV
NRREESTRDH TIERPAFGIQ KGEFEHSETR EGETQGVAFE HESSADFRNS QSPIQDQDKS
QLSGGEQQSS DAGLFKEEGG LDFLGRQDTD YRSMEYRDVD HRLPGSQMFG YGQSKSFPEG
KTARDAQRDL QDQDYRTGPS EEKPSRLIRL SGVPENATKE EILNAFRTPD GMPVKNLQLK
EYNTGYDYGY VCVEFSLLED AIGCMEANQG TLMIQDKEVT LEYVPSLDFW YCKRCKASIG
GHRSSCSFCK NPREVTEAKQ ELVTYPQPQK TSIPAPLEKQ PNQPLRATDK EPEPRKREEG
QESRLGYQKR EAERYLPPSR REGPAFRRDR EKESWSGETR QDGESKTIML KRIYRSTPPE
VIVEVLEPYV RLTTANVRII KNRTGPMGHT YGFIDLDSHA EALRVVKILQ NLDPPFSIDG
KMVAVNLATG KRRNDTGDHS DHMHYYQGKK YFRDRRGGGR NSDWSSDTNR QGQQSSSDCY
IYDSATGYYY DPLAGTYYDP NTQQEVYVPQ DPGLLEEEEI KEKKPTSQGK SSSKKEMSKR
DGKEKKDRGV MRFQENASEG KAPAEDVFKK PLPPTVKKEE SPPPPKMVNP LIGLLGEYGG
DSDYEEEEEE EQTPPPQPRI AQPQKREELP KKENEEDKLT DWNKLACLLC RRQFPNKEVL
IKHQQLSDLH KQNLEIHRKI KQSEQELAYL ERREREGKFK ERGNDRREKL QSFDSPERKR
IKYSRESDSD RKLVDKEDTD TSSKGGCVQQ ATGWRKGAGL GYGHPGLAPS EEAEGRMRGP
SVGAPGRTSK RQSNETYRDA VRRVMFARYK ELD
//
