ID   A0A2K6P647_RHIRO        Unreviewed;       805 AA.
AC   A0A2K6P647;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   SubName: Full=APC membrane recruitment protein 1 {ECO:0000313|Ensembl:ENSRROP00000012015.1};
GN   Name=AMER1 {ECO:0000313|Ensembl:ENSRROP00000012015.1};
OS   Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Rhinopithecus.
OX   NCBI_TaxID=61622 {ECO:0000313|Ensembl:ENSRROP00000012015.1, ECO:0000313|Proteomes:UP000233200};
RN   [1] {ECO:0000313|Ensembl:ENSRROP00000012015.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the Amer family.
CC       {ECO:0000256|ARBA:ARBA00007750}.
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DR   AlphaFoldDB; A0A2K6P647; -.
DR   STRING; 61622.ENSRROP00000012015; -.
DR   Ensembl; ENSRROT00000036131.1; ENSRROP00000012015.1; ENSRROG00000030333.1.
DR   GeneTree; ENSGT00530000063529; -.
DR   OMA; KPMEACA; -.
DR   Proteomes; UP000233200; Unplaced.
DR   GO; GO:0016604; C:nuclear body; IEA:Ensembl.
DR   GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR   GO; GO:0008013; F:beta-catenin binding; IEA:Ensembl.
DR   GO; GO:1904713; F:beta-catenin destruction complex binding; IEA:Ensembl.
DR   GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IEA:Ensembl.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0045732; P:positive regulation of protein catabolic process; IEA:Ensembl.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; IEA:Ensembl.
DR   InterPro; IPR019003; AMER.
DR   PANTHER; PTHR22237:SF0; APC MEMBRANE RECRUITMENT PROTEIN 1; 1.
DR   PANTHER; PTHR22237; UNCHARACTERIZED; 1.
DR   Pfam; PF09422; AMER; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233200}.
FT   REGION          1..115
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          156..309
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          339..406
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          448..478
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          592..649
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          737..767
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        223..237
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        339..363
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        372..406
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        455..474
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   805 AA;  87877 MW;  A4A512F0D8A49A98 CRC64;
     METQKDEAAQ AKGAAASGST HEQTTEKGAK NKAAKATEGP TSEPSSSGPG RLKKTAMKLF
     GGKKGICTLP SFFGGGRSKG SGKGSSKKSL SKSKTHDGLS EAAHGPEDVV SDGTGFSLPL
     PELPCRFPSS QSAHGALETG SRCNTSVAGA TEKAVAEKFP SMPKPKKGLK GFFSSIRRHR
     KSKVTGAEQS EPGAKGPERV KARPHEHVSA APQVPCSEET FQAPRKENAN PQDASGPKVS
     PTPEPSPPTT EKMACKDPEK PMEACASAHV QPKPAPESSS LEEPHSPETG EKVVAGEVNP
     PNGPVGDQLS LLFGDVTSLK SFDSLTGCGD IIAEQDMDSM TDSMASGGQR ANRDGTKRSS
     CLVTYQGGGE EMALPDDDDE EEEEEEEEVE LEEEEEEVKE EEEDDDLEYL WATAQMYPRP
     DMNLGYHPTT SPGHHGYMLL DPVRSYPGLA PGELLTPQSD QQESAPNSDE GYYDSTTPGF
     EDDSGEALGL VHRDCLPRDS YSGDALYEFY EPDDSLENSP PGDDCLYDLH GRSSEMFDPF
     LNFEPFSSSR PPGAMETEEE RLVTIQKQLL YWELRREQLE AQEARAREAR AREAHTREAY
     TRESHGREAY AREAHTWEAR GREARTREPQ AREARSRETQ VREAQARQEK PVLEYQMRPL
     GPSVMGLAAG LSGTSQISHR GITSAFPTTA SSEPDWRDFR PLEKRYEGTC SKKDQSTCLM
     QLFQSDAMFE PDMQEANFGG SPRRAYPTYS PPEDPEEEEV EKEGNATVSF SQALVEFTSN
     GNLFSSIRCP GTEDKRQVTQ ACGTW
//