ID A0A2K6P6U6_RHIRO Unreviewed; 1327 AA.
AC A0A2K6P6U6;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Immunoglobulin superfamily member 1 {ECO:0000313|Ensembl:ENSRROP00000012267.1};
GN Name=IGSF1 {ECO:0000313|Ensembl:ENSRROP00000012267.1};
OS Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Rhinopithecus.
OX NCBI_TaxID=61622 {ECO:0000313|Ensembl:ENSRROP00000012267.1, ECO:0000313|Proteomes:UP000233200};
RN [1] {ECO:0000313|Ensembl:ENSRROP00000012267.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_010368735.1; XM_010370433.1.
DR Ensembl; ENSRROT00000036384.1; ENSRROP00000012267.1; ENSRROG00000030440.1.
DR GeneID; 104667855; -.
DR CTD; 3547; -.
DR GeneTree; ENSGT01100000263478; -.
DR OrthoDB; 5355093at2759; -.
DR Proteomes; UP000233200; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:UniProt.
DR Gene3D; 2.60.40.10; Immunoglobulins; 12.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013151; Immunoglobulin.
DR PANTHER; PTHR11738; MHC CLASS I NK CELL RECEPTOR; 1.
DR PANTHER; PTHR11738:SF159; PLATELET GLYCOPROTEIN VI; 1.
DR Pfam; PF00047; ig; 1.
DR Pfam; PF13895; Ig_2; 5.
DR Pfam; PF13927; Ig_3; 1.
DR SMART; SM00409; IG; 10.
DR SMART; SM00408; IGc2; 10.
DR SUPFAM; SSF48726; Immunoglobulin; 12.
DR PROSITE; PS50835; IG_LIKE; 6.
PE 4: Predicted;
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000233200};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..1327
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014424677"
FT TRANSMEM 511..530
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 542..561
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 29..97
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 312..384
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 410..475
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 768..860
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 864..933
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1056..1125
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 1297..1319
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1304..1319
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1327 AA; 147998 MW; B8EDF493CDE16BEC CRC64;
MTLDRRGEGA TMLKTFTVLL FCILMDPQPE LWIESNYPQA PWENITLWCR SPSRISSKFL
LLKDKTQMTW IRPSHKTFQV SFLIGALTES SAGLYRCCYW KEPGWSKPSK VLELEAPGQL
PKPIFWIQAE TPPLPGCNVN ILCHGWLQDL VFMLFKEGYA EPVDYQVPTG TMAIFSIDNL
TPEDEGVYIC RTHIQMLPTL WSEPSNPLKL VVAGLYPKPT LTVHPGPIMA PGESLNLRCQ
GPIYGMTFAL MRVEDLEKSF YHKKTIKNEA YFFFQSLKIQ DTGHYLCFYY DASYRGSLLS
DVLKIWVTDT FPKTWLLARP SPVVQMGQNV SLRCRGPVDG VGLALYKKGE DKPVQFLDAT
SIDDNTSFFL NNVTYSDTGI YSCQYLLTWK TSIRMPSHNT VELMVVDKPP KPSLSAWPST
VFKLGKAITL RCRVSHPVLE FSLEWEERGT FQKFSVDGDF IISNVDGKGT GTYSCSYRVE
THPNIWSHRS EPLKLMGPAG YLTWNYVLNE AIRLSLIVQL VALLLVVLWI RWKCRRLRIR
EAWLLGTAQG VTMLFIVTAL LCCGLCNGVL IEETEIVMPT PKPELWAETN FPLAPWKNLT
LWCRSPSGST KEFVLLKDGT GWIATRPASE QVRAAFPLGA LTQSHTGSYH CHSWEEMAVS
EPSEALELLG TDILPKPVIS ASPPIRGQEL QLRCKGWLAG MGFALYKEGQ QEPVQQLGAV
GREAFFTIQR MEDKDEGNYS CRTHTEQRPF KWSEPSEPLE LVIKEMYPKP FFKTWASPVV
TPGARVTFNC STPHQHMSFI LYKDGSEIAS SDRSWASPGA SAAHFLIISV GIGDGGNYSC
RYYDFSIWSE PSDPVELVVT EFYPKPTLLA QPGPVVFPGK SVTLRCQGTF QGMRFALLQE
GAQVPLQFQS VSGNSADFLL HTVGAEDSGN YSCIYYETTM SNRGSYLSIP LMIWVTDTFP
KPWLLAEPSS VVPMGQNVTL WCRGPVHGVG YILHKEEEAT SMQLWGSTSN DGAFPITNIS
GASMGRYSCC YHPDWTSSIK IQPSNTLELI VTGLLPKPSL LAQPGPMVSP GENMTLQCQG
ELPDSTFVLL KEGTQEPLEQ QRPSGYRADF WMPAVRGEDS GIYSCVYYLD SAPFAASNHS
DSLEIWVTDK PPKPSLSAWP GTMFKLGKDI ILQCRGPLPG VEFVLEHDGE EAPQQFSEDG
DFVINNVEGK GIGNYSCSYR LQAYPDIWSE PSDSLELVGA AGPVAQECTV GNIVRSSLIV
VVVVALGVVL AIEWKKWPRL RTRGSETDGR DQTIALEECN QEGEPGTPAN SPSSTSRRIS
VELPVPI
//
