ID A0A2K6P7F3_RHIRO Unreviewed; 260 AA.
AC A0A2K6P7F3;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=CD27 molecule {ECO:0000313|Ensembl:ENSRROP00000012465.1};
GN Name=CD27 {ECO:0000313|Ensembl:ENSRROP00000012465.1};
OS Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Rhinopithecus.
OX NCBI_TaxID=61622 {ECO:0000313|Ensembl:ENSRROP00000012465.1, ECO:0000313|Proteomes:UP000233200};
RN [1] {ECO:0000313|Ensembl:ENSRROP00000012465.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00206}.
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DR RefSeq; XP_010384254.1; XM_010385952.1.
DR AlphaFoldDB; A0A2K6P7F3; -.
DR STRING; 61622.ENSRROP00000012465; -.
DR Ensembl; ENSRROT00000036584.1; ENSRROP00000012465.1; ENSRROG00000030539.1.
DR GeneID; 104680120; -.
DR KEGG; rro:104680120; -.
DR CTD; 939; -.
DR GeneTree; ENSGT00510000049297; -.
DR OMA; LSTHWSP; -.
DR OrthoDB; 4711092at2759; -.
DR Proteomes; UP000233200; Unplaced.
DR GO; GO:0009897; C:external side of plasma membrane; IEA:Ensembl.
DR GO; GO:0043027; F:cysteine-type endopeptidase inhibitor activity involved in apoptotic process; IEA:Ensembl.
DR GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR GO; GO:0097191; P:extrinsic apoptotic signaling pathway; IEA:Ensembl.
DR GO; GO:0070233; P:negative regulation of T cell apoptotic process; IEA:Ensembl.
DR GO; GO:0045579; P:positive regulation of B cell differentiation; IEA:InterPro.
DR GO; GO:0046330; P:positive regulation of JNK cascade; IEA:Ensembl.
DR GO; GO:0045582; P:positive regulation of T cell differentiation; IEA:InterPro.
DR CDD; cd13408; TNFRSF7; 1.
DR Gene3D; 2.10.50.10; Tumor Necrosis Factor Receptor, subunit A, domain 2; 1.
DR InterPro; IPR001368; TNFR/NGFR_Cys_rich_reg.
DR InterPro; IPR022328; TNFR_7.
DR InterPro; IPR034000; TNFRSF7_N.
DR PANTHER; PTHR47496; CD27; 1.
DR PANTHER; PTHR47496:SF1; CD27 ANTIGEN; 1.
DR Pfam; PF00020; TNFR_c6; 1.
DR PRINTS; PR01960; TNFACTORR7.
DR SMART; SM00208; TNFR; 2.
DR SUPFAM; SSF57586; TNF receptor-like; 2.
DR PROSITE; PS00652; TNFR_NGFR_1; 1.
DR PROSITE; PS50050; TNFR_NGFR_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000233200};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..260
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014407181"
FT TRANSMEM 189..211
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 64..104
FT /note="TNFR-Cys"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DOMAIN 64..104
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|PROSITE:PS50050"
FT REGION 218..260
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 260 AA; 29069 MW; 7EBD5B2FF41A50C0 CRC64;
MARPHPWWLC FLGTLVGLSA TPAPKSCPER HYWAQGKLCC QMCEPGTFLV KDCDQHRKAA
QCDPCIPGVS FSPDHHTRPH CESCRHCNSG LLIRNCTITA NAVCACRNGW QCRDKECTEC
DPPPNPSLTT WPSQALGPHP QPTHLPYVSE MLEARTAGHM QTLADFRQLP ARTLSTHWPP
QRSLCSSDFI RILVIFSGMF LVFTLAGALF LHQQRKYRSN KGESPMGPAE PCPYSCPREE
EGSTIPIQED YRKPEPASSP
//
