ID   A0A2K6P7Q4_RHIRO        Unreviewed;       279 AA.
AC   A0A2K6P7Q4;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   RecName: Full=Sodium/potassium-transporting ATPase subunit beta {ECO:0000256|RuleBase:RU362099};
GN   Name=ATP1B3 {ECO:0000313|Ensembl:ENSRROP00000012524.1};
OS   Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Rhinopithecus.
OX   NCBI_TaxID=61622 {ECO:0000313|Ensembl:ENSRROP00000012524.1, ECO:0000313|Proteomes:UP000233200};
RN   [1] {ECO:0000313|Ensembl:ENSRROP00000012524.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- FUNCTION: This is the non-catalytic component of the active enzyme,
CC       which catalyzes the hydrolysis of ATP coupled with the exchange of
CC       Na(+) and K(+) ions across the plasma membrane. The exact function of
CC       the beta-3 subunit is not known. {ECO:0000256|ARBA:ARBA00037667}.
CC   -!- SUBUNIT: The sodium/potassium-transporting ATPase is composed of a
CC       catalytic alpha subunit, an auxiliary non-catalytic beta subunit and an
CC       additional regulatory subunit. Interacts with catalytic alpha subunit
CC       ATP12A. {ECO:0000256|ARBA:ARBA00038625}.
CC   -!- SUBCELLULAR LOCATION: Apical cell membrane
CC       {ECO:0000256|ARBA:ARBA00004655}; Single-pass type II membrane protein
CC       {ECO:0000256|ARBA:ARBA00004655}. Basolateral cell membrane
CC       {ECO:0000256|ARBA:ARBA00037810}; Single-pass type II membrane protein
CC       {ECO:0000256|ARBA:ARBA00037810}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004606}; Single-pass type II membrane protein
CC       {ECO:0000256|ARBA:ARBA00004606}.
CC   -!- SIMILARITY: Belongs to the X(+)/potassium ATPases subunit beta family.
CC       {ECO:0000256|ARBA:ARBA00005876, ECO:0000256|RuleBase:RU362099}.
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DR   RefSeq; XP_010376574.1; XM_010378272.1.
DR   AlphaFoldDB; A0A2K6P7Q4; -.
DR   STRING; 61622.ENSRROP00000012524; -.
DR   Ensembl; ENSRROT00000036644.1; ENSRROP00000012524.1; ENSRROG00000030567.1.
DR   GeneID; 104674060; -.
DR   KEGG; rro:104674060; -.
DR   CTD; 483; -.
DR   GeneTree; ENSGT01030000234579; -.
DR   OMA; WVPEIYN; -.
DR   OrthoDB; 2880589at2759; -.
DR   Proteomes; UP000233200; Unplaced.
DR   GO; GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016323; C:basolateral plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005890; C:sodium:potassium-exchanging ATPase complex; IEA:InterPro.
DR   GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR   GO; GO:0006814; P:sodium ion transport; IEA:InterPro.
DR   Gene3D; 2.60.40.1660; Na, k-atpase alpha subunit; 1.
DR   InterPro; IPR000402; Na/K_ATPase_sub_beta.
DR   InterPro; IPR038702; Na/K_ATPase_sub_beta_sf.
DR   NCBIfam; TIGR01107; Na_K_ATPase_bet; 1.
DR   PANTHER; PTHR11523; SODIUM/POTASSIUM-DEPENDENT ATPASE BETA SUBUNIT; 1.
DR   PANTHER; PTHR11523:SF47; SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-3; 1.
DR   Pfam; PF00287; Na_K-ATPase; 1.
DR   PROSITE; PS00390; ATPASE_NA_K_BETA_1; 1.
PE   3: Inferred from homology;
KW   Ion transport {ECO:0000256|RuleBase:RU362099};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362099};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233200};
KW   Signal-anchor {ECO:0000256|ARBA:ARBA00022968};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU362099};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU362099}; Transport {ECO:0000256|RuleBase:RU362099}.
FT   TRANSMEM        38..62
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362099"
SQ   SEQUENCE   279 AA;  31480 MW;  4C357A5B7B63D252 CRC64;
     MTKNEKKSLN QSLAEWKLFI YNPTTGELLG RTAKSWGLIL LFYLVFYGFL AALFSFTMWV
     MLQTLNDEVP KYRDQIPSPG LMVFPKPVTA LEYTFSRSDP TSYAGYIEDL KEFLKPYTLE
     EQKNLTVCPD GALFEQKGPV YVACQFPISL LQACSGMNDP DFGYSQGNPC ILVKMNRIIG
     LKPEGVPRID CVSKNEDIPN VAVYPHNGMI DLKYFPYYGK KLHVGYLQPL VAVQVSFAPN
     NTGKEVTVEC KIDGSANLKS QDDRDKFLGR VMFKITARA
//