ID   A0A2K6P8F9_RHIRO        Unreviewed;      1290 AA.
AC   A0A2K6P8F9;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Cytoplasmic linker associated protein 2 {ECO:0000313|Ensembl:ENSRROP00000012832.1};
GN   Name=CLASP2 {ECO:0000313|Ensembl:ENSRROP00000012832.1};
OS   Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Rhinopithecus.
OX   NCBI_TaxID=61622 {ECO:0000313|Ensembl:ENSRROP00000012832.1, ECO:0000313|Proteomes:UP000233200};
RN   [1] {ECO:0000313|Ensembl:ENSRROP00000012832.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   Ensembl; ENSRROT00000036954.1; ENSRROP00000012832.1; ENSRROG00000030491.1.
DR   GeneTree; ENSGT00940000155574; -.
DR   Proteomes; UP000233200; Unplaced.
DR   GO; GO:0015630; C:microtubule cytoskeleton; IEA:UniProt.
DR   GO; GO:0008017; F:microtubule binding; IEA:UniProt.
DR   GO; GO:0051494; P:negative regulation of cytoskeleton organization; IEA:UniProt.
DR   GO; GO:1902904; P:negative regulation of supramolecular fiber organization; IEA:UniProt.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 3.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR024395; CLASP_N_dom.
DR   InterPro; IPR034085; TOG.
DR   PANTHER; PTHR21567; CLASP; 1.
DR   PANTHER; PTHR21567:SF30; CLIP-ASSOCIATING PROTEIN 2; 1.
DR   Pfam; PF21040; CEP104-like_TOG; 1.
DR   Pfam; PF12348; CLASP_N; 1.
DR   SMART; SM01349; TOG; 3.
DR   SUPFAM; SSF48371; ARM repeat; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000233200}.
FT   DOMAIN          90..323
FT                   /note="TOG"
FT                   /evidence="ECO:0000259|SMART:SM01349"
FT   DOMAIN          627..881
FT                   /note="TOG"
FT                   /evidence="ECO:0000259|SMART:SM01349"
FT   DOMAIN          1047..1283
FT                   /note="TOG"
FT                   /evidence="ECO:0000259|SMART:SM01349"
FT   REGION          17..67
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          320..374
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          425..468
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          489..562
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          597..625
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          874..924
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          948..991
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        440..468
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        489..532
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        603..625
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        954..969
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1290 AA;  141167 MW;  3069F4651589A4C7 CRC64;
     MRRLICKRIC DYKSFDDEES VDGNRPSSAA SAFKVPAPKT SGNPVNSARK PGSAGGPKVG
     GASKEGGAGA VDEDDFIKAF TDVPSVQIYS SRELEETLNK IREILSDDKH DWDQRANALK
     KIRSLLVAGA AQYDCFFQHL RLLDGALKLS AKDLRSQVVR EACITVAHLS TVLGNKFDHG
     AEAIVPTLFN LVPNSAKVMA TSGCAAIRFI IRHTHVPRLI PLITSNCTSK SVPVRRRSFE
     FLDLLLQEWQ THSLERHAAV LVETIKKGIH DADAEARVEA RKTYMGLRNH FPGEAETLYN
     SLEPSYQKSL QTYLKSSGSV ASLPQSDRSS SSSQESLNRP FSSKWSTANP STVAGRVSAG
     SSKASSLPGS LQRSRSDIDV NAAAGAKAHH AAGQSVRNGR LGAGALNPGS YASLGRVRAK
     LSAPLAGMGN AKTDSRGRSR TKMVSQSQRS SSPDKNEAGS RSGSPGRVLT TTALSTVSSG
     VQRVLVNSAS AQKRSKIPRS QGCSREASPS RLSVARSSRI PRPSVSQGCS REASRESSRD
     TSPVRSFQPL GPGYGISQSS RLSSSVSAMR VLNTGSDVEE AVADALKKPA RRRYESYGMH
     SDDDANSDAS SACSERSYSS RNGSIPTYMR QTEDVAEVLN RCASSNWSER KEGLLGLQNL
     LKNQRTLSRV ELKRLCEIFT RMFADPHGKV FSMFLETLVD FIQVHKDDLQ DWLFVLLTQL
     LKKMGADLLG SVQAKVQKAL DVTRESFPND LQFNILMRFT VDQTQTPSLK TVKPALRDQL
     HSFWSSKVKV AILKYIETLA KQMDPGDFIN SSETRLAVSR VITWTTEPKS SDVRKAAQSV
     LISLFELNTP EFTMLLGALP KTFQDGATKL LHNHLRNTGN GTQSSMGSPL TRPAPRSPAN
     WSSPLTSPTN TSQNTLSPSA FDYDTENMNS EDIYSSLRGV TEAIQNFSFR SQEDMNEPLK
     RDSKKDDGDS MCGGPGMSDP RAGGDATDSS QTALDNKASL LHSVPTHSSP RSRDYNPYNY
     SDSISPFNKS ALKEAMFDDD ADQFPDDLSL DHSDLVAELL KELSNHNERV EERKIALYEL
     MKLTQEESFS VWDEHFKTIL LLLLETLGDK EPTIRALALK VLREILRHQP ARFKNYAELT
     VMKTLEAHKD PHKEVVRSAE EAASVLATSI SPEQCIKVLC PIIQTADYPI NLAAIKMQTK
     VIERVSKETL NLLLPEIMPG LIQGYDNSES SVRKACVFCL VAVHAVIGDE LKPHLSQLTG
     SKMKLLNLYI KRAQTGSGGA DPTTDVSGQS
//