ID   A0A2K6PBN2_RHIRO        Unreviewed;       389 AA.
AC   A0A2K6PBN2;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   RecName: Full=NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial {ECO:0000256|ARBA:ARBA00017279, ECO:0000256|PIRNR:PIRNR000543};
GN   Name=NDUFA10 {ECO:0000313|Ensembl:ENSRROP00000013941.1};
OS   Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Rhinopithecus.
OX   NCBI_TaxID=61622 {ECO:0000313|Ensembl:ENSRROP00000013941.1, ECO:0000313|Proteomes:UP000233200};
RN   [1] {ECO:0000313|Ensembl:ENSRROP00000013941.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- FUNCTION: Accessory subunit of the mitochondrial membrane respiratory
CC       chain NADH dehydrogenase (Complex I), that is believed not to be
CC       involved in catalysis. Complex I functions in the transfer of electrons
CC       from NADH to the respiratory chain. The immediate electron acceptor for
CC       the enzyme is believed to be ubiquinone.
CC       {ECO:0000256|ARBA:ARBA00003195, ECO:0000256|PIRNR:PIRNR000543}.
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974,
CC         ECO:0000256|PIRNR:PIRNR000543};
CC   -!- SUBUNIT: Complex I is composed of 45 different subunits. This a
CC       component of the hydrophobic protein fraction.
CC       {ECO:0000256|ARBA:ARBA00011514}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion matrix
CC       {ECO:0000256|ARBA:ARBA00004305, ECO:0000256|PIRNR:PIRNR000543}.
CC   -!- SIMILARITY: Belongs to the complex I NDUFA10 subunit family.
CC       {ECO:0000256|ARBA:ARBA00008606, ECO:0000256|PIRNR:PIRNR000543}.
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DR   AlphaFoldDB; A0A2K6PBN2; -.
DR   Ensembl; ENSRROT00000038067.1; ENSRROP00000013941.1; ENSRROG00000031189.1.
DR   GeneTree; ENSGT00390000016151; -.
DR   Proteomes; UP000233200; Unplaced.
DR   GO; GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
DR   GO; GO:0005747; C:mitochondrial respiratory chain complex I; IEA:InterPro.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; IEA:InterPro.
DR   CDD; cd02030; NDUO42; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR031314; DNK_dom.
DR   InterPro; IPR015828; NDUFA10.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR10513; DEOXYNUCLEOSIDE KINASE; 1.
DR   PANTHER; PTHR10513:SF15; NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 10, MITOCHONDRIAL; 1.
DR   Pfam; PF01712; dNK; 1.
DR   PIRSF; PIRSF000543; NADH_UQ_42KD; 2.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   Electron transport {ECO:0000256|ARBA:ARBA00022982,
KW   ECO:0000256|PIRNR:PIRNR000543};
KW   FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|PIRNR:PIRNR000543};
KW   Flavoprotein {ECO:0000256|ARBA:ARBA00022630,
KW   ECO:0000256|PIRNR:PIRNR000543};
KW   Mitochondrion {ECO:0000256|PIRNR:PIRNR000543};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233200};
KW   Respiratory chain {ECO:0000256|ARBA:ARBA00022660,
KW   ECO:0000256|PIRNR:PIRNR000543};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR000543}.
FT   DOMAIN          60..275
FT                   /note="Deoxynucleoside kinase"
FT                   /evidence="ECO:0000259|Pfam:PF01712"
SQ   SEQUENCE   389 AA;  44837 MW;  8A2FAE67DE9E28B8 CRC64;
     MAFRLLKLAP RSASARVLAA GVQRVRGIHS SVQCKLRYGM WHFLFGDKIS KRLTEHSRVI
     TVDGNICTGK GRLAKEVAEK LGFKHFPEAG IHYADSTTGD GKPLAIEYSG NLSLEKFYDD
     PRSNDGHSYR LQSWLYSSRL LQYSDALEHL LTTGQGVVLE RSIFSDFVFL DAMYNQGFVR
     KQCVDHYNEV KNVTACDYLP PHLVIYIDVP VPEVQRRIQK KGDPHEMKIT SAYLQDIENA
     YKKTFLPEMS EKCEILQYSA REAEDSTRVV EDIEYLKFEK GPWLQQDDRS LHHLRLLVQD
     KFDVLNYTSI PVYLPEITIG AYQTDRVFRQ FRALGIPYPR WAARSEREGP EMLLTGLWRG
     DLLIGFQLPG RKYSPGYNTE VGDKWIWLK
//