ID A0A2K6PBU1_RHIRO Unreviewed; 167 AA.
AC A0A2K6PBU1;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=Claudin domain containing 2 {ECO:0000313|Ensembl:ENSRROP00000014037.1};
GN Name=CLDND2 {ECO:0000313|Ensembl:ENSRROP00000014037.1};
OS Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Rhinopithecus.
OX NCBI_TaxID=61622 {ECO:0000313|Ensembl:ENSRROP00000014037.1, ECO:0000313|Proteomes:UP000233200};
RN [1] {ECO:0000313|Ensembl:ENSRROP00000014037.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the PMP-22/EMP/MP20 family.
CC {ECO:0000256|ARBA:ARBA00006864}.
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DR RefSeq; XP_010367905.1; XM_010369603.1.
DR AlphaFoldDB; A0A2K6PBU1; -.
DR Ensembl; ENSRROT00000038164.1; ENSRROP00000014037.1; ENSRROG00000031236.1.
DR GeneID; 104667264; -.
DR KEGG; rro:104667264; -.
DR CTD; 125875; -.
DR GeneTree; ENSGT01050000244814; -.
DR OMA; NDVFFSW; -.
DR OrthoDB; 4842737at2759; -.
DR Proteomes; UP000233200; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 1.20.140.150; -; 1.
DR InterPro; IPR004031; PMP22/EMP/MP20/Claudin.
DR InterPro; IPR004032; PMP22_EMP_MP20.
DR PANTHER; PTHR10671:SF30; CLAUDIN DOMAIN-CONTAINING PROTEIN 2; 1.
DR PANTHER; PTHR10671; EPITHELIAL MEMBRANE PROTEIN-RELATED; 1.
DR Pfam; PF00822; PMP22_Claudin; 1.
DR PROSITE; PS01221; PMP22_1; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000233200};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 61..83
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 95..116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 128..150
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 167 AA; 18051 MW; AFABA2A042D23279 CRC64;
MGVKRSLQRG GILLSLVANV LMVLSTATNY WTRQQEGHSG LWQECNHGIC SNIPCQTTLA
VTAACMVLAV GVGVVGMVMG LRIRCNEGES LRGQTTSAFL FLGGLLLLTA LIGYTVKNAW
KNNVFFSWSY FSGWLALPFS ILAGFCFLLA DMIMQSTDAI SGFPVCL
//
