ID   A0A2K6PCJ1_RHIRO        Unreviewed;       171 AA.
AC   A0A2K6PCJ1;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=Protein phosphatase 1 regulatory subunit 1B {ECO:0000256|ARBA:ARBA00020090};
DE   AltName: Full=DARPP-32 {ECO:0000256|ARBA:ARBA00029874};
DE   AltName: Full=Dopamine- and cAMP-regulated neuronal phosphoprotein {ECO:0000256|ARBA:ARBA00030254};
GN   Name=PPP1R1B {ECO:0000313|Ensembl:ENSRROP00000014248.1};
OS   Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Rhinopithecus.
OX   NCBI_TaxID=61622 {ECO:0000313|Ensembl:ENSRROP00000014248.1, ECO:0000313|Proteomes:UP000233200};
RN   [1] {ECO:0000313|Ensembl:ENSRROP00000014248.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- FUNCTION: Inhibitor of protein-phosphatase 1.
CC       {ECO:0000256|ARBA:ARBA00002900}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   -!- SIMILARITY: Belongs to the protein phosphatase inhibitor 1 family.
CC       {ECO:0000256|ARBA:ARBA00007775}.
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DR   AlphaFoldDB; A0A2K6PCJ1; -.
DR   Ensembl; ENSRROT00000038375.1; ENSRROP00000014248.1; ENSRROG00000031338.1.
DR   GeneTree; ENSGT00730000111283; -.
DR   Proteomes; UP000233200; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004864; F:protein phosphatase inhibitor activity; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   InterPro; IPR008466; PPP1R1A/B/C.
DR   PANTHER; PTHR15417:SF2; PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 1B; 1.
DR   PANTHER; PTHR15417; PROTEIN PHOSPHATASE INHIBITOR AND DOPAMINE- AND CAMP-REGULATED NEURONAL PHOSPHOPROTEIN; 1.
DR   Pfam; PF05395; DARPP-32; 2.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233200}.
FT   REGION          1..23
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          60..171
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        84..105
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        133..148
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   171 AA;  19505 MW;  755C69D54F2F5BB8 CRC64;
     MDPKDRKKIQ FSVPAPPSQL DPRQVEMIRR RRPTPAMLFR LSEHSSPAVQ RIAESHLQSI
     SNLNENQASE EEDELGELRE LGYPREEDEE EEEEDEEEEE EEDSQAEVLK VIRQSAGQKT
     TCGQGLEGPW ERPPPLDEPE RDGSSEDQVE DPALSEPWEE PQHPSPSEPG T
//