ID A0A2K6PQ95_RHIRO Unreviewed; 383 AA.
AC A0A2K6PQ95;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=FA complementation group L {ECO:0000313|Ensembl:ENSRROP00000018702.1};
GN Name=FANCL {ECO:0000313|Ensembl:ENSRROP00000018702.1};
OS Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Rhinopithecus.
OX NCBI_TaxID=61622 {ECO:0000313|Ensembl:ENSRROP00000018702.1, ECO:0000313|Proteomes:UP000233200};
RN [1] {ECO:0000313|Ensembl:ENSRROP00000018702.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A2K6PQ95; -.
DR STRING; 61622.ENSRROP00000018702; -.
DR Ensembl; ENSRROT00000042863.1; ENSRROP00000018702.1; ENSRROG00000033391.1.
DR GeneTree; ENSGT00390000005537; -.
DR Proteomes; UP000233200; Unplaced.
DR GO; GO:0000785; C:chromatin; IEA:Ensembl.
DR GO; GO:0043240; C:Fanconi anaemia nuclear complex; IEA:Ensembl.
DR GO; GO:0016604; C:nuclear body; IEA:Ensembl.
DR GO; GO:0005635; C:nuclear envelope; IEA:Ensembl.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:Ensembl.
DR GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:Ensembl.
DR GO; GO:0007276; P:gamete generation; IEA:Ensembl.
DR GO; GO:0036297; P:interstrand cross-link repair; IEA:InterPro.
DR GO; GO:0006513; P:protein monoubiquitination; IEA:Ensembl.
DR GO; GO:0042127; P:regulation of cell population proliferation; IEA:Ensembl.
DR CDD; cd16490; RING-CH-C4HC3_FANCL; 1.
DR Gene3D; 3.10.110.20; RWD domain-like; 1.
DR Gene3D; 3.10.110.10; Ubiquitin Conjugating Enzyme; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR026848; Fancl.
DR InterPro; IPR026850; FANCL_C.
DR InterPro; IPR043898; FANCL_d2.
DR InterPro; IPR044037; FANCL_d3.
DR InterPro; IPR043003; FANCL_d3_sf.
DR InterPro; IPR019162; FancL_WD-rpt_cont_dom.
DR InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13206:SF0; E3 UBIQUITIN-PROTEIN LIGASE FANCL; 1.
DR PANTHER; PTHR13206; UBIQUITIN LIGASE PROTEIN PHF9 FANCONI ANEMIA GROUP L PROTEIN; 1.
DR Pfam; PF11793; FANCL_C; 1.
DR Pfam; PF09765; FANCL_d1; 1.
DR Pfam; PF18890; FANCL_d2; 1.
DR Pfam; PF18891; FANCL_d3; 1.
DR SMART; SM01197; FANCL_C; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000233200}.
FT DOMAIN 6..92
FT /note="Fanconi anemia complex subunit FancL WD-repeat
FT containing"
FT /evidence="ECO:0000259|Pfam:PF09765"
FT DOMAIN 108..197
FT /note="FANCL UBC-like"
FT /evidence="ECO:0000259|Pfam:PF18890"
FT DOMAIN 200..294
FT /note="FANCL UBC-like"
FT /evidence="ECO:0000259|Pfam:PF18891"
FT DOMAIN 304..364
FT /note="FANCL C-terminal"
FT /evidence="ECO:0000259|Pfam:PF11793"
SQ SEQUENCE 383 AA; 43685 MW; 70FFBA788D38A6AE CRC64;
MAVTEASLLR QCPLLLPQNR SKTVYEGFIS AQGRDFHLRV VLPEDLQLKN ARLLCSWQLR
TILNGYHQIV QQRMQHSPDL MSFMMELKML LEVALKNRQE LYAPPPPPQF YSSLIEEIGT
LGWDKLVYVD TCFSTIKLKA EDASGREHLI TLKLKAKYPA ESPDCFVDFP VPFSASRTPQ
SSLISIYSQF LAAIESLKAF WDVMDEIDEK TWVLEPEKPP RCATARRIAL GNNVSINIEV
DPRHPTMLPE CFFLGADHVV KPLGIKLSRN IHLWDPENSV LQNLKDVLEI DFPARAILEK
SDFTMDCGIC YAYQLDGAIP DQVCDNSQCG QPFHQICLYE WLRGLLTSRQ SFNIIFGECP
YCSKVSKLLI TSHKMCLAFS NMF
//
