ID A0A2K6PZA1_RHIRO Unreviewed; 339 AA.
AC A0A2K6PZA1;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Protein tyrosine phosphatase non-receptor type 20 {ECO:0000313|Ensembl:ENSRROP00000021856.1};
GN Name=PTPN20 {ECO:0000313|Ensembl:ENSRROP00000021856.1};
OS Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Rhinopithecus.
OX NCBI_TaxID=61622 {ECO:0000313|Ensembl:ENSRROP00000021856.1, ECO:0000313|Proteomes:UP000233200};
RN [1] {ECO:0000313|Ensembl:ENSRROP00000021856.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_010382034.1; XM_010383732.1.
DR RefSeq; XP_010382035.1; XM_010383733.1.
DR RefSeq; XP_010382036.1; XM_010383734.1.
DR AlphaFoldDB; A0A2K6PZA1; -.
DR Ensembl; ENSRROT00000046050.1; ENSRROP00000021856.1; ENSRROG00000034822.1.
DR GeneID; 104678450; -.
DR CTD; 26095; -.
DR GeneTree; ENSGT00940000160066; -.
DR OrthoDB; 1342035at2759; -.
DR Proteomes; UP000233200; Unplaced.
DR GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
DR GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR InterPro; IPR000242; PTP_cat.
DR InterPro; IPR016130; Tyr_Pase_AS.
DR InterPro; IPR003595; Tyr_Pase_cat.
DR InterPro; IPR000387; Tyr_Pase_dom.
DR PANTHER; PTHR46900:SF3; FERM AND PDZ DOMAIN-CONTAINING 2; 1.
DR PANTHER; PTHR46900; TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 13; 1.
DR Pfam; PF00102; Y_phosphatase; 1.
DR PRINTS; PR00700; PRTYPHPHTASE.
DR SMART; SM00194; PTPc; 1.
DR SMART; SM00404; PTPc_motif; 1.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR PROSITE; PS00383; TYR_PHOSPHATASE_1; 1.
DR PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
DR PROSITE; PS50055; TYR_PHOSPHATASE_PTP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000233200}.
FT DOMAIN 78..331
FT /note="Tyrosine-protein phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS50055"
FT DOMAIN 250..322
FT /note="Tyrosine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS50056"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 339 AA; 39131 MW; 5D2D0DFFDE203D56 CRC64;
MWTARGPFRR DRWSSENEEP AGPSQALSPL LSDTHKIVSE GELHQLAQIR PLIFNFHEQT
AIKDCLKMLE KKTGTYDIMQ EFMALELKNL PGEFNSGNQP SNREKNRYRD ILPYDSTRVP
LGKSKDYINA SYIRIVNCGQ EYFYIATQGP LLSTIDDFWQ MVLENNCNVI AMITREIEGG
VIKCYPYWPI SLKKPLELKH FRVFLENYQI LQCFIIRMFQ VVEKSTGTSH SVKQLQFTKW
PDHGTPASAD SFIKYVRYAR KSHLTGPMVV HCSAGIGRTG VFLCVDVVFC AIVKNCSFNI
MDIVAQMREQ RSGMVQTKEQ YHFCYDIVLK VLRKLLTLD
//
