ID A0A2K6PZE6_RHIRO Unreviewed; 321 AA.
AC A0A2K6PZE6;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=MutS homolog 6 {ECO:0000313|Ensembl:ENSRROP00000021884.1};
GN Name=MSH6 {ECO:0000313|Ensembl:ENSRROP00000021884.1};
OS Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Rhinopithecus.
OX NCBI_TaxID=61622 {ECO:0000313|Ensembl:ENSRROP00000021884.1, ECO:0000313|Proteomes:UP000233200};
RN [1] {ECO:0000313|Ensembl:ENSRROP00000021884.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A2K6PZE6; -.
DR Ensembl; ENSRROT00000046078.1; ENSRROP00000021884.1; ENSRROG00000034827.1.
DR GeneTree; ENSGT00550000075024; -.
DR Proteomes; UP000233200; Unplaced.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR Gene3D; 1.10.1420.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11361:SF148; DNA MISMATCH REPAIR PROTEIN MSH6; 1.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR Pfam; PF00488; MutS_V; 1.
DR SMART; SM00534; MUTSac; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000233200}.
FT DOMAIN 176..192
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
SQ SEQUENCE 321 AA; 35698 MW; 002DED5C169A6C00 CRC64;
MRRLFYNFDK NYKDWQSAVE CIAVLDVLLC LANYSRGGDG PMCRPVILLP EDTPPFLELK
GSRHPCITKT FFGDDFIPND ILIGCEEEEQ ENGKASCVLV TGPNMGDLFL PHPQAGLLAV
MAQMGCYVPA EVCRLTPIDR VFTRLGASDR IMSGESTFFV ELSETASILT HATAHSLVLV
DELGRGTATF DGTAIANAVV KELAETIKCR TLFSTHYHSL RALLLLAHAC MVENECEDPS
QETITFLYKF IKGACPKSYG FNAARLANLP EEVIQKGHRK AREFEKMNQS LRLFREVCLA
SERSTVDAEA VHKLLTLIKE L
//
