ID A0A2K6Q117_RHIRO Unreviewed; 489 AA.
AC A0A2K6Q117;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE SubName: Full=Interferon gamma receptor 1 {ECO:0000313|Ensembl:ENSRROP00000022477.1};
GN Name=IFNGR1 {ECO:0000313|Ensembl:ENSRROP00000022477.1};
OS Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Rhinopithecus.
OX NCBI_TaxID=61622 {ECO:0000313|Ensembl:ENSRROP00000022477.1, ECO:0000313|Proteomes:UP000233200};
RN [1] {ECO:0000313|Ensembl:ENSRROP00000022477.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the type II cytokine receptor family.
CC {ECO:0000256|ARBA:ARBA00005399}.
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DR RefSeq; XP_010377792.1; XM_010379490.1.
DR AlphaFoldDB; A0A2K6Q117; -.
DR STRING; 61622.ENSRROP00000022477; -.
DR Ensembl; ENSRROT00000046674.1; ENSRROP00000022477.1; ENSRROG00000035100.1.
DR GeneID; 104675021; -.
DR KEGG; rro:104675021; -.
DR CTD; 3459; -.
DR GeneTree; ENSGT00510000048929; -.
DR OMA; NIMLPKS; -.
DR OrthoDB; 5356432at2759; -.
DR Proteomes; UP000233200; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR GO; GO:0019955; F:cytokine binding; IEA:InterPro.
DR GO; GO:0004906; F:type II interferon receptor activity; IEA:Ensembl.
DR GO; GO:0038196; P:type III interferon-mediated signaling pathway; IEA:Ensembl.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR021126; IFN_gamma_rc_D2_pox/mammal.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR008355; Interferon_gamma_rcpt_asu.
DR PANTHER; PTHR20859:SF5; INTERFERON GAMMA RECEPTOR 1; 1.
DR PANTHER; PTHR20859; INTERFERON/INTERLEUKIN RECEPTOR; 1.
DR Pfam; PF07140; IFNGR1_D2; 1.
DR Pfam; PF20634; IFNGR1_transm; 1.
DR Pfam; PF01108; Tissue_fac; 1.
DR PRINTS; PR01777; INTERFERONGR.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000233200};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..489
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014404597"
FT TRANSMEM 247..270
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 13..112
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|Pfam:PF01108"
FT DOMAIN 132..240
FT /note="Interferon gamma receptor D2"
FT /evidence="ECO:0000259|Pfam:PF07140"
FT REGION 327..436
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 373..401
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 414..433
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 489 AA; 54547 MW; F91916AEF2353FDC CRC64;
MALLFLLILV MQSVSRAEMV TADLGQSSVP IPTNVTIESY NMNTIVYWEY QSMPRVSVFT
VEVKNYGVKN AEWIDACINI SHHYCNISDH VGDPSNSLWV RVKARVGQKE SAYAESKEFA
VCRDGKIGPP KLDIRKEEKQ IMIDVFHPSV FVNGEEQEVD YDPETTCYIK VYNVYVRMNG
SEIQYKILTQ KEDDCDEIQC QLAIPVSSLN SQYCVSAEGV LHVWGVTTEK SKEVCITIFN
SNIKGSLWIP IVAALLLFLV LSLVLICFYI KKINPLKEKS IILPKSLISV VRSATLETKP
ESKYVSLITS YQPFSLEKEV VCEEPLSPAT VPGMHTEDNP GKGEHTEELS SITEVVTTEE
NIPDMAPGSH LTPIERESSS PFSSNQSEPC SVALNSYHSR NCSDSDHSRN GFDTDSSCLE
SHNSLSDSEF PPNNKGEIKT EGQELITVIK APTSFGYDKP HVLVDLLVDD GRKESLIGYR
PTEGSKEFS
//
