ID A0A2K6Q1E0_RHIRO Unreviewed; 469 AA.
AC A0A2K6Q1E0;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Keratin 36 {ECO:0000313|Ensembl:ENSRROP00000022595.1};
OS Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Rhinopithecus.
OX NCBI_TaxID=61622 {ECO:0000313|Ensembl:ENSRROP00000022595.1, ECO:0000313|Proteomes:UP000233200};
RN [1] {ECO:0000313|Ensembl:ENSRROP00000022595.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|RuleBase:RU000685}.
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DR RefSeq; XP_010356881.1; XM_010358579.1.
DR AlphaFoldDB; A0A2K6Q1E0; -.
DR SMR; A0A2K6Q1E0; -.
DR Ensembl; ENSRROT00000046793.1; ENSRROP00000022595.1; ENSRROG00000035145.1.
DR GeneID; 104658515; -.
DR KEGG; rro:104658515; -.
DR CTD; 3861; -.
DR GeneTree; ENSGT00940000154602; -.
DR OrthoDB; 4640531at2759; -.
DR Proteomes; UP000233200; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR002957; Keratin_I.
DR PANTHER; PTHR23239; INTERMEDIATE FILAMENT; 1.
DR PANTHER; PTHR23239:SF368; KERATIN, TYPE I CYTOSKELETAL 14; 1.
DR Pfam; PF00038; Filament; 1.
DR PRINTS; PR01248; TYPE1KERATIN.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 2.
DR SUPFAM; SSF46579; Prefoldin; 1.
DR PROSITE; PS00226; IF_ROD_1; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|RuleBase:RU000685};
KW Reference proteome {ECO:0000313|Proteomes:UP000233200}.
FT DOMAIN 112..423
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT REGION 423..469
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 116..150
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 215..408
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 423..446
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 447..469
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 469 AA; 51342 MW; A16B4442E2706C3C CRC64;
MTTCSRQFTS SSSMKGSFGG GIGGGSSRIS SVLAGGSCRA PSTYGGGLSV SSSRFSSGGA
YGLGGGYGGG FSSSSSFGSG FGGGYGGGLG AGLGGGLGGG FAGGDGLLVG SEKVTMQNLN
DRLASYLDKV RALEEANADL EVKIRDWYQR QRPAEIKDYS PYFKTIEDLR NKILTATVDN
ANVLLQIDNA RLAADDFRTK YETELNLRMS VEADINGLRR VLDELTLARA DLEMQIESLK
EELAYLKKNH EEEMNALRGQ VGGDVNVEMD AAPGVDLSRI LNEMRDQYEK MAEKNRKDAE
EWFFTKTEEL NREVATNSEL VQSGKSEISE LRRTVQNLEI ELQSQLSMKA SLENSLEETK
GRYCMQLAQI QEMIGSVEEQ LAQLRCEMEQ QNQEYKILLD VKTRLEQEIA TYRRLLEGED
AHLSSSQFSS GSQSSRDVTS SSRQIRTKVM DVHDGKVVST HEQVLRTKN
//
