ID A0A2K6Q3Y8_RHIRO Unreviewed; 223 AA.
AC A0A2K6Q3Y8;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Serine/threonine/tyrosine interacting protein {ECO:0000313|Ensembl:ENSRROP00000023502.1};
GN Name=STYX {ECO:0000313|Ensembl:ENSRROP00000023502.1};
OS Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Rhinopithecus.
OX NCBI_TaxID=61622 {ECO:0000313|Ensembl:ENSRROP00000023502.1, ECO:0000313|Proteomes:UP000233200};
RN [1] {ECO:0000313|Ensembl:ENSRROP00000023502.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_010370372.1; XM_010372070.1.
DR AlphaFoldDB; A0A2K6Q3Y8; -.
DR STRING; 61622.ENSRROP00000023502; -.
DR Ensembl; ENSRROT00000047706.1; ENSRROP00000023502.1; ENSRROG00000035593.1.
DR GeneID; 104669165; -.
DR KEGG; rro:104669165; -.
DR CTD; 6815; -.
DR GeneTree; ENSGT00940000154859; -.
DR OMA; EWRYEMR; -.
DR OrthoDB; 3035478at2759; -.
DR Proteomes; UP000233200; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:1990444; F:F-box domain binding; IEA:Ensembl.
DR GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
DR GO; GO:0001691; F:pseudophosphatase activity; IEA:Ensembl.
DR GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR GO; GO:0045204; P:MAPK export from nucleus; IEA:Ensembl.
DR GO; GO:0062026; P:negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process; IEA:Ensembl.
DR GO; GO:0070372; P:regulation of ERK1 and ERK2 cascade; IEA:Ensembl.
DR CDD; cd14522; DSP_STYX; 1.
DR Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR InterPro; IPR000340; Dual-sp_phosphatase_cat-dom.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR InterPro; IPR000387; Tyr_Pase_dom.
DR InterPro; IPR020422; TYR_PHOSPHATASE_DUAL_dom.
DR PANTHER; PTHR46588; SERINE/THREONINE/TYROSINE-INTERACTING PROTEIN; 1.
DR PANTHER; PTHR46588:SF1; SERINE_THREONINE_TYROSINE-INTERACTING PROTEIN; 1.
DR Pfam; PF00782; DSPc; 1.
DR SMART; SM00195; DSPc; 1.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
DR PROSITE; PS50054; TYR_PHOSPHATASE_DUAL; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000233200}.
FT DOMAIN 28..176
FT /note="Tyrosine-protein phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS50054"
FT DOMAIN 96..154
FT /note="Tyrosine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS50056"
FT REGION 197..223
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 223 AA; 25521 MW; C36A5BA752EF4BFD CRC64;
MEDMKLEFPS LPQCKEDAEE WTYPMRREMQ EILPGLFLGP YSSAMKSKLP ILQKHGITHI
ICIRQNIEAN FIKPNFQQLF RYLVLDIADN PVENIIRFFP MTKEFIDGSL QTGGKVLVHG
NAGISRSAAF VIAYIMETFG MKYRDAFAYV QERRFCINPN AGFVHQLQEY EAIYLAKLTI
QMMSPLQIER SLSVHSGTTG SLKRTHEEED DFGNMQVATA QNG
//
