ID A0A2K6Q740_RHIRO Unreviewed; 1307 AA.
AC A0A2K6Q740;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=RIMS binding protein 2 {ECO:0000313|Ensembl:ENSRROP00000024601.1};
GN Name=RIMBP2 {ECO:0000313|Ensembl:ENSRROP00000024601.1};
OS Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Rhinopithecus.
OX NCBI_TaxID=61622 {ECO:0000313|Ensembl:ENSRROP00000024601.1, ECO:0000313|Proteomes:UP000233200};
RN [1] {ECO:0000313|Ensembl:ENSRROP00000024601.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the RIMBP family.
CC {ECO:0000256|ARBA:ARBA00010749}.
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DR STRING; 61622.ENSRROP00000024601; -.
DR Ensembl; ENSRROT00000048814.1; ENSRROP00000024601.1; ENSRROG00000036099.1.
DR GeneTree; ENSGT00950000183203; -.
DR OMA; KEEAYCR; -.
DR Proteomes; UP000233200; Unplaced.
DR CDD; cd00063; FN3; 3.
DR CDD; cd12014; SH3_RIM-BP_1; 1.
DR CDD; cd12012; SH3_RIM-BP_2; 1.
DR CDD; cd12013; SH3_RIM-BP_3; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR Gene3D; 2.30.30.40; SH3 Domains; 3.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR035753; RIM-BP_SH3_2.
DR InterPro; IPR035755; RIM-BP_SH3_3.
DR InterPro; IPR040325; RIMBP1/2/3.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR14234; RIM BINDING PROTEIN-RELATED; 1.
DR PANTHER; PTHR14234:SF18; RIMS-BINDING PROTEIN 2; 1.
DR Pfam; PF07653; SH3_2; 2.
DR Pfam; PF14604; SH3_9; 1.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00060; FN3; 3.
DR SMART; SM00326; SH3; 3.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
DR SUPFAM; SSF50044; SH3-domain; 3.
DR PROSITE; PS50853; FN3; 1.
DR PROSITE; PS50002; SH3; 3.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000233200};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 184..251
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 506..607
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1103..1171
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 1207..1274
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 134..181
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 601..632
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 644..683
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 714..733
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 744..803
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 848..878
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 963..1098
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1284..1307
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1..74
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 601..619
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 751..771
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 785..803
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 991..1014
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1307 AA; 144034 MW; EFB988C844C497C0 CRC64;
MREAAERRQQ LELEHEQALA VLSAKQQEID LLQKAQVEAK KEHEGAVRLL ESKVRELEEK
CRTQSEQFNL LSRDLEKFRQ HAGKIDLLGG STVAPLDVST APGKPFPQFV NGLATSLGKG
QESAIGGGSA IGEYIRPLPQ PGDRPEPLSA KPTFLSRSGS PRCRSESDME NERNSNTSKQ
RYSGKVHLCV ARYSYNPFDG PNENPEAELP LTAGKYLYVY GDMDEDGFYE GELLDGQRGL
VPSNFVDFVQ DNESRLASTL GNEQDQNFIN HSGIGLEGEH ILDLHSPTHT DAGITDNSAG
TLDVNIDDIG EDIVPYPRKI TLIKQLAKSV IVGWEPPAVP PGWGTVSSYN VLVDKETRMN
LTLGSRTKAL IEKLNMAACT YRISVQCVTS RGSSDELQCT LLVGKDVVVA PSHLRVDNIT
QISAQLSWLP TNSNYSHVIF LNEEEFDIVK AARYKYQFFN LRPNMAYKVK VLAKPHQMPW
QLPLEQREKK EAFVEFSTLP AGPPAPPQDV TVQAGATPAT IRVSWRPPVL TPSGLSNGAN
VTGYGVYAKG QRVAEVIFPT ADSTAVELVR LRSLEAKGVT VRTLSAQGES VDSAVAAVPP
ELLVPPTPHP RPAPQSKPLP SSGVPDTKDE RLGPHARMDE AWEQSRAPGP VHGHTLEPPA
GPGRRSPSPS RILPQPQGTP VSTTVAKAMA REAAQRVAES SRLEKRSVFL ERSSAGQYAA
SDEEDAYDSP DFKRRGASVD DFLKGSELGK QPHCCHGDEY HTESSRGSDL SDIMEEDEEE
LYSEMQLEDG GRRRPSGTSH NALKDCTEHR TSEGTFWEPE FPHQPHRKRL FSIPEVAEED
GECCGLLHKQ GAGPSPRART GLAREPRPGR PCRGDEAPRG SWFSVKHRGS GAVPHVEDFL
LEDRGCRFSR SATRSPDSGL DCGSEEEESR FGFGNTVATC SPGPGHCPCR RGLRPLLARR
RTLTRQSSVE EDFGEQVGPG GVLRNDDPQP SPERPLPRKH GWGEPTEHQD FRGVWKKSIT
MPDSRAAAPH AKPPPRVAQG PLILGNPASA GRVDHMGRRF PRGSAGPQRS RPVTVPSIDD
YGRDRLSPDF YEESETDPGA EELPARIFVA LFDYDPLTMS PNPDAAEEEL PFKEGQIIKV
YGDKDADGFY RGETCARLGL IPCNMVSEIQ ADDEEMMDQL LRQGFLPLNT PVEKIERSRR
SGRHHSVSTR RMVALYDYDP RESSPNVDVE AELTFCTGDI ITVFGEIDED GFYYGELNGQ
KGLVPSNFLE EVPDDVEVYL SDAPSHYSQD TPMRSKAKRK KSVHFTP
//
