ID   A0A2K6Q8Y0_RHIRO        Unreviewed;       402 AA.
AC   A0A2K6Q8Y0;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 25.
DE   RecName: Full=TGF-beta family profile domain-containing protein {ECO:0000259|PROSITE:PS51362};
OS   Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Rhinopithecus.
OX   NCBI_TaxID=61622 {ECO:0000313|Ensembl:ENSRROP00000025238.1, ECO:0000313|Proteomes:UP000233200};
RN   [1] {ECO:0000313|Ensembl:ENSRROP00000025238.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the TGF-beta family.
CC       {ECO:0000256|ARBA:ARBA00006656, ECO:0000256|RuleBase:RU000354}.
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DR   AlphaFoldDB; A0A2K6Q8Y0; -.
DR   STRING; 61622.ENSRROP00000025238; -.
DR   Ensembl; ENSRROT00000049454.1; ENSRROP00000025238.1; ENSRROG00000036368.1.
DR   GeneTree; ENSGT00940000155272; -.
DR   OMA; DRDIFHQ; -.
DR   Proteomes; UP000233200; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR   GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR   CDD; cd19398; TGF_beta_BMP8; 1.
DR   Gene3D; 2.60.120.970; -; 1.
DR   Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR   InterPro; IPR029034; Cystine-knot_cytokine.
DR   InterPro; IPR001839; TGF-b_C.
DR   InterPro; IPR001111; TGF-b_propeptide.
DR   InterPro; IPR015615; TGF-beta-rel.
DR   InterPro; IPR017948; TGFb_CS.
DR   PANTHER; PTHR11848:SF119; BONE MORPHOGENETIC PROTEIN 8A-RELATED; 1.
DR   PANTHER; PTHR11848; TGF-BETA FAMILY; 1.
DR   Pfam; PF00019; TGF_beta; 1.
DR   Pfam; PF00688; TGFb_propeptide; 1.
DR   PRINTS; PR00669; INHIBINA.
DR   SMART; SM00204; TGFB; 1.
DR   SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR   PROSITE; PS00250; TGF_BETA_1; 1.
DR   PROSITE; PS51362; TGF_BETA_2; 1.
PE   3: Inferred from homology;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Growth factor {ECO:0000256|ARBA:ARBA00023030,
KW   ECO:0000256|RuleBase:RU000354};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233200};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           25..402
FT                   /note="TGF-beta family profile domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5014434944"
FT   DOMAIN          268..402
FT                   /note="TGF-beta family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS51362"
SQ   SEQUENCE   402 AA;  44681 MW;  E42E5B2F0EF897EA CRC64;
     MAALPGPLWL LGLALCAMGG GGPGLRPPPG CPQRCLGASE RRDVQREILS VLGLPGRPRL
     RAAPSGPRLP ASAPLFMLDL YHAMTGDDDK DDAPAERRLG RADLVMSFVN MVERDHALGH
     QEPHWKEFRF DLTQIPDGEA VTAAEFRIYK VPSIHLLNRT LHVSMFQVVQ EQSNRESDLL
     FLDLQTLQAG DEGWLVLDVT AASDRWLLKR HKDLGLRLYV ETEDGHSVDP GLAGLLGQRA
     PRSRQPFVVT FFRASPSPIR TPRAVRPLRR RQPKKTNELP QANRLPGIFD DVHGSHGQQV
     CRRHELYVSF QDLGWLDWVI APQGYSAYYC EGECSFPLGS CMNATNHAIL QSLVHLMTPD
     AVPKACCAPT KLSATSVLYY DSSNNVILRK HRNMVVKACG CH
//