ID   A0A2K6QC99_RHIRO        Unreviewed;       301 AA.
AC   A0A2K6QC99;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=Death effector domain containing {ECO:0000313|Ensembl:ENSRROP00000026410.1};
GN   Name=DEDD {ECO:0000313|Ensembl:ENSRROP00000026410.1};
OS   Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Rhinopithecus.
OX   NCBI_TaxID=61622 {ECO:0000313|Ensembl:ENSRROP00000026410.1, ECO:0000313|Proteomes:UP000233200};
RN   [1] {ECO:0000313|Ensembl:ENSRROP00000026410.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC       {ECO:0000256|ARBA:ARBA00004604}.
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DR   AlphaFoldDB; A0A2K6QC99; -.
DR   Ensembl; ENSRROT00000050652.1; ENSRROP00000026410.1; ENSRROG00000036948.1.
DR   GeneTree; ENSGT00390000008714; -.
DR   OMA; QAWPEEE; -.
DR   Proteomes; UP000233200; Unplaced.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006915; P:apoptotic process; IEA:InterPro.
DR   GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR   CDD; cd08790; DED_DEDD; 1.
DR   Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR   InterPro; IPR011029; DEATH-like_dom_sf.
DR   InterPro; IPR001875; DED_dom.
DR   InterPro; IPR038856; DEDD/DEDD2.
DR   InterPro; IPR049341; TRADD-like_N.
DR   PANTHER; PTHR15205; DEATH EFFECTOR DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR15205:SF2; DEATH EFFECTOR DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF01335; DED; 1.
DR   Pfam; PF20694; TRADD-like_N; 1.
DR   SMART; SM00031; DED; 1.
DR   SUPFAM; SSF47986; DEATH domain; 1.
DR   PROSITE; PS50168; DED; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233200};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          25..103
FT                   /note="DED"
FT                   /evidence="ECO:0000259|PROSITE:PS50168"
FT   REGION          128..147
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          160..191
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        132..147
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   301 AA;  34810 MW;  909A37ACB855A291 CRC64;
     MAGLKRQASQ VWPEEHGEQE HGLYSLHRMF DIVGTHLTHR DVRVLSFLFV DVIDDHERGL
     IRNGRDFLLA LERQGRCDES NFRQVLQLLR IITRHDLLPY VTLKRRRAVC PDLVDKYLEE
     TSIRYVTPRA LSDPEPRPPQ PPKTVPPHYP VVCCPTSGPQ MCSKRPARGR ATLGSQRKRR
     KSVTPDPKEK QTCDIRLRVR AEYCQHETAL QGNVFSNKQD PLERQFERFN QANTILKSRD
     LGSIICDIKF SELTYLDAFW RDYINGSLLE ALKGVFITDS LKQAVGHEAI KLLNFLKTKK
     L
//