ID A0A2K6QCS9_RHIRO Unreviewed; 582 AA.
AC A0A2K6QCS9;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Complement component 4 binding protein alpha {ECO:0000313|Ensembl:ENSRROP00000026571.1};
GN Name=C4BPA {ECO:0000313|Ensembl:ENSRROP00000026571.1};
OS Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Rhinopithecus.
OX NCBI_TaxID=61622 {ECO:0000313|Ensembl:ENSRROP00000026571.1, ECO:0000313|Proteomes:UP000233200};
RN [1] {ECO:0000313|Ensembl:ENSRROP00000026571.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00302}.
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DR RefSeq; XP_010363945.1; XM_010365643.1.
DR STRING; 61622.ENSRROP00000026571; -.
DR Ensembl; ENSRROT00000050823.1; ENSRROP00000026571.1; ENSRROG00000037028.1.
DR Ensembl; ENSRROT00000050825.1; ENSRROP00000026573.1; ENSRROG00000037028.1.
DR GeneID; 104664184; -.
DR KEGG; rro:104664184; -.
DR CTD; 722; -.
DR GeneTree; ENSGT00940000154640; -.
DR OMA; CEYIVCH; -.
DR OrthoDB; 4551607at2759; -.
DR Proteomes; UP000233200; Unplaced.
DR GO; GO:0005615; C:extracellular space; IEA:Ensembl.
DR GO; GO:0045959; P:negative regulation of complement activation, classical pathway; IEA:Ensembl.
DR GO; GO:0045732; P:positive regulation of protein catabolic process; IEA:Ensembl.
DR GO; GO:1903027; P:regulation of opsonization; IEA:Ensembl.
DR GO; GO:0009609; P:response to symbiotic bacterium; IEA:Ensembl.
DR CDD; cd00033; CCP; 8.
DR Gene3D; 1.20.5.3730; -; 1.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 8.
DR InterPro; IPR040514; C4bp_oligo.
DR InterPro; IPR035976; Sushi/SCR/CCP_sf.
DR InterPro; IPR000436; Sushi_SCR_CCP_dom.
DR PANTHER; PTHR19325:SF564; C4B-BINDING PROTEIN ALPHA CHAIN; 1.
DR PANTHER; PTHR19325; COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING; 1.
DR Pfam; PF18453; C4bp_oligo; 1.
DR Pfam; PF00084; Sushi; 8.
DR SMART; SM00032; CCP; 8.
DR SUPFAM; SSF57535; Complement control module/SCR domain; 8.
DR PROSITE; PS50923; SUSHI; 7.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00302}; Reference proteome {ECO:0000313|Proteomes:UP000233200};
KW Signal {ECO:0000256|SAM:SignalP};
KW Sushi {ECO:0000256|ARBA:ARBA00022659, ECO:0000256|PROSITE-
KW ProRule:PRU00302}.
FT SIGNAL 1..32
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 33..582
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014561728"
FT DOMAIN 32..95
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 96..157
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 158..221
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 222..281
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 282..347
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 409..467
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 468..525
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DISULFID 66..93
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 252..279
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 496..523
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
SQ SEQUENCE 582 AA; 65181 MW; 450931EA4AC84684 CRC64;
MAAWPFSRLW KVSDPILFQM TLVAALLPAI LGNCGPPPTL SFAAPVNITT LTETHFETGT
TLKYTCRPGY ARSHSDQMLT CNSDGQWTYT TFCVHKRCRH PGDLPNGQVE IKTDLLFGSE
IEFSCSEGFV LIGSTTSHCE VQDRGVGWSH PLPQCEIVKC EPPPDIRNGR HSGEEDFYTY
GFSVTYSCDS RFSLLGHASI SCTVENKTTG VWRPSPPTCE KITCHKPDVS HGEIVSGFGP
IYNYKDAIVF NCQRGFVLRG SSVIRCGADS KWDPSPPACE PNSCTNLPDI PHASWETYPR
PKKEDVYVVG TILRYRCHPG YKPTTDAPTT LICQKNLRWT PYQGCEALCC PEPKLDSAQI
TQHRKNRPAN HCVYFYGDEI LFSCHGVRRL SAICQPDGTW SPQTPSCGDN CNIPPKIAHG
HYKQTGIYSI FKEEFTYECE KGYILVGQAT LSCSNSRWSA PAPRCKALCL KPELVNGRLS
VDKNQYVEPE NVTIQCDSGY GMVGPKSITC SENRTWYPEV PRCEWETPEG CEQVLAGKRL
MQCFPNPEDV KMALEVYKLS LEIEQLELQR DRARQSTLDK EL
//
