ID A0A2K6QIL5_RHIRO Unreviewed; 1712 AA.
AC A0A2K6QIL5;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=Myosin heavy chain 7B {ECO:0000313|Ensembl:ENSRROP00000028624.1};
GN Name=MYH7B {ECO:0000313|Ensembl:ENSRROP00000028624.1};
OS Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Rhinopithecus.
OX NCBI_TaxID=61622 {ECO:0000313|Ensembl:ENSRROP00000028624.1, ECO:0000313|Proteomes:UP000233200};
RN [1] {ECO:0000313|Ensembl:ENSRROP00000028624.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|ARBA:ARBA00008314,
CC ECO:0000256|PROSITE-ProRule:PRU00782}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR Ensembl; ENSRROT00000052989.1; ENSRROP00000028624.1; ENSRROG00000038094.1.
DR GeneTree; ENSGT00940000160950; -.
DR OMA; CYLRQGY; -.
DR Proteomes; UP000233200; Unplaced.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0032982; C:myosin filament; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:InterPro.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.340; -; 4.
DR Gene3D; 1.20.5.370; -; 4.
DR Gene3D; 1.20.5.4820; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR002928; Myosin_tail.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014751; XRCC4-like_C.
DR PANTHER; PTHR45615; MYOSIN HEAVY CHAIN, NON-MUSCLE; 1.
DR PANTHER; PTHR45615:SF29; MYOSIN-7B; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF01576; Myosin_tail_1; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF90257; Myosin rod fragments; 6.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50096; IQ; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|PROSITE-ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175};
KW Muscle protein {ECO:0000256|ARBA:ARBA00023179};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000233200};
KW Thick filament {ECO:0000256|ARBA:ARBA00022433}.
FT DOMAIN 1..556
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT REGION 433..455
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 1675..1712
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1712 AA; 195479 MW; F08BDDFBDA647B53 CRC64;
MEAFGNAKTL RNDNSSRFGK FIRIHFGPSG KLASADIDSY LLEKSRVIFQ LPGERSYHVY
YQILSGKKPE LQDMLLLSMN PYDYHFCSQG VITVDNMNDG EELIATDHAM DILGFSVDEK
CACYKIVGAL LHFGNMKFKQ KQREEQAEAD GTESADKAAY LMGVSSGDLL KGLLHPRVRV
GNEYVTKGQS VEQVVFAVGA LAKATYDRLF RWLVSRINQT LDTKLPRQFF IGVLDIAGFE
IFEFNSFEQL CINFTNEKLQ QFFNQHMFVL EQEEYKREGI DWVFIDFGLD LQPCIDLIEK
PLGILSILEE ECMFPKASDA SFRAKLYDNH AGKSPNFQQP RPDKKRKYQA HFEVVHYAGV
VPYSIVGWLE KNKDPLNETV VPIFQKSQNR LLATLYENYA GSCSTEPPKS GVKEKRKKAA
SFQTVSQLHK ENLNKLMTNL RATQPHFVRC IVPNENKTPG VMDAFLVLHQ LRCNGVLEGI
RICRQGFPNR LLYTDFRQRY RILNPSAIPD DTFMDSRKAT EKLLGSLDLD HAQYQFGHTK
VFFKAGLLGV LEELRDQRLA KVLTLLQARS RGRLMRLEYQ RLLGGRDALF TIQWNIRAFN
AVKNWSWMKL FFKMKPLLRS AQAEEELAAL RAELRGLRGA LAAAEAKRQE LEETHVSVTQ
EKNDLALQLQ AEQDNLADAE ERCHLLIKSK VQLEGKVKEL SERLEDEEEV NADLAARRRK
LEDECTELKK DIDDLELTLA KAEKEKQATE NKVKNLTEEM AALDESVARL TKEKKALQEA
HQQALGDLQA EEDRVSALTK AKLRLEQQVE DLECSLEQEK KLRMDTERAK RKLEGDLKLT
QESVADATQD KQQLEEKLKK KDSELSQLSL RVEDEQLLGA QLQKKIKELQ ARAEELEEEL
EAERAARARV EKQRAEAARE LEELSERLEE AGGASAGQRE GCRKREAELG RLRRELEEAA
LRHEATVAAL RRKQAEGAAE LGEQVDSLQR VRQKLEKEKS ELRMEVDDLA ANVETLTRAK
ASAEKLCRTY EDQLSEAKIK VEELQRQLAD ASTQRGRLQT ESGELSRLLE EKECLISQLS
RGKALAAQSL EELRRQLEEE SKAKSALAHA VQALRHDCDL LREQHEEEAE AQAELQRLLS
KANAEVAQWR SKYEADAIQR TEELEEAKKK LALRLQEAEE GVEAANAKCS SLEKAKLRLQ
TESEDVTLEL ERATSAAAAL DKKQRHLERA LEERRRQEEE MQRELEAAQR EARGLGTELF
RLQHSHEEAL EALETLKREN KNLQEEISDL TDQVSLSGKS IQELEKAKKA LEGEKSEIQA
ALEEAEGALE LEETKTLRIQ LELSQVKAEV DRKLAEKDEE CANLRRNHQR AVESLQASLD
AETRARNEAL RLKKKMEGDL NDLELQLGHA TRQATEAQAA TRLMQAQLKE EQAGRDEEQR
LAAELREQAQ ALERRAALLA AELEELRAAL EQGERSRRLA EQELLEATER LNLLHSQNTG
LLNQKKKLEA DLTQLSGEVE EAAQERQEAE EKAKKAITDA AMMAEELKKE QDTSAHLERM
KKTLEQTVRE LQARLEEAEQ AALRGGKKQV QKLEAKVREL EAELDAEQKK HAEALKGVRK
HERRVKELAY QAEEDRKNLA RMQDLVDKLQ SKVKSYKRQF EEAEQQANTN LAKYRKAQHE
LDDAEERADM AETQANKLRA RTRDALGPKH KE
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