ID A0A2K6QKZ9_RHIRO Unreviewed; 354 AA.
AC A0A2K6QKZ9;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Z-DNA binding protein 1 {ECO:0000313|Ensembl:ENSRROP00000029449.1};
GN Name=ZBP1 {ECO:0000313|Ensembl:ENSRROP00000029449.1};
OS Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Rhinopithecus.
OX NCBI_TaxID=61622 {ECO:0000313|Ensembl:ENSRROP00000029449.1, ECO:0000313|Proteomes:UP000233200};
RN [1] {ECO:0000313|Ensembl:ENSRROP00000029449.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_010363425.1; XM_010365123.1.
DR AlphaFoldDB; A0A2K6QKZ9; -.
DR Ensembl; ENSRROT00000053849.1; ENSRROP00000029449.1; ENSRROG00000038526.1.
DR GeneTree; ENSGT00390000002234; -.
DR Proteomes; UP000233200; Unplaced.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003726; F:double-stranded RNA adenosine deaminase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0060340; P:positive regulation of type I interferon-mediated signaling pathway; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR025735; RHIM_dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR InterPro; IPR042371; Z_dom.
DR InterPro; IPR042361; ZBP1.
DR PANTHER; PTHR14966; Z-DNA-BINDING PROTEIN 1; 1.
DR PANTHER; PTHR14966:SF0; Z-DNA-BINDING PROTEIN 1; 1.
DR Pfam; PF12721; RHIM; 1.
DR SMART; SM00550; Zalpha; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50139; Z_BINDING; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000233200};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT DOMAIN 28..91
FT /note="Z-binding"
FT /evidence="ECO:0000259|PROSITE:PS50139"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 142..176
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 267..319
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 291..319
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 354 AA; 38428 MW; BD689CC423E64F8E CRC64;
MAQAPADPGR EAERPQQYAA TIPETPNPQF SQQREEDIYR FLKDNGPQRA LVIAQALGMR
TAKDVNRDLY RMKSRHLLDV DEQSKVWTIY RPEDSGRRAE SASIIYQHNP INMICQNGPN
GQISIANSKA IQIGHGNIIT RQTASGEDGS TGPRHLPSMA PGHSSTQGTL NDPWEPQDIH
MERSMLRWVQ LGHSNEMRLH SVPSEGPAHI PPGSPPVSAT AAGPEALFEA RMPSPRTHPK
GDAAQRIHMK SCFLEYATIG NSNKMSISPG VAGPGGVAGS GDGKTGEDAG PRPTDTQSRS
HFPQDIGQPI TRNSSKLTPK LEAMTLGNRS HKAAEGSDYV DETSHYGSWW GGGI
//
