ID   A0A2K6QLD6_RHIRO        Unreviewed;       949 AA.
AC   A0A2K6QLD6;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=Utrophin {ECO:0008006|Google:ProtNLM};
OS   Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Rhinopithecus.
OX   NCBI_TaxID=61622 {ECO:0000313|Ensembl:ENSRROP00000029597.1, ECO:0000313|Proteomes:UP000233200};
RN   [1] {ECO:0000313|Ensembl:ENSRROP00000029597.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A2K6QLD6; -.
DR   Ensembl; ENSRROT00000053998.1; ENSRROP00000029597.1; ENSRROG00000038583.1.
DR   GeneTree; ENSGT00940000153467; -.
DR   Proteomes; UP000233200; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0045202; C:synapse; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd16247; EFh_UTRO; 1.
DR   CDD; cd00176; SPEC; 2.
DR   CDD; cd00201; WW; 1.
DR   CDD; cd02334; ZZ_dystrophin; 1.
DR   Gene3D; 1.20.58.60; -; 3.
DR   Gene3D; 2.20.70.10; -; 1.
DR   Gene3D; 3.30.60.90; -; 1.
DR   Gene3D; 1.10.238.10; EF-hand; 2.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR015153; EF-hand_dom_typ1.
DR   InterPro; IPR015154; EF-hand_dom_typ2.
DR   InterPro; IPR018159; Spectrin/alpha-actinin.
DR   InterPro; IPR002017; Spectrin_repeat.
DR   InterPro; IPR001202; WW_dom.
DR   InterPro; IPR036020; WW_dom_sf.
DR   InterPro; IPR000433; Znf_ZZ.
DR   InterPro; IPR043145; Znf_ZZ_sf.
DR   PANTHER; PTHR12268; E3 UBIQUITIN-PROTEIN LIGASE KCMF1; 1.
DR   PANTHER; PTHR12268:SF26; UTROPHIN; 1.
DR   Pfam; PF09068; EF-hand_2; 1.
DR   Pfam; PF09069; EF-hand_3; 1.
DR   Pfam; PF00435; Spectrin; 1.
DR   Pfam; PF00569; ZZ; 1.
DR   SMART; SM00150; SPEC; 3.
DR   SMART; SM00456; WW; 1.
DR   SMART; SM00291; ZnF_ZZ; 1.
DR   SUPFAM; SSF47473; EF-hand; 2.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   SUPFAM; SSF46966; Spectrin repeat; 2.
DR   SUPFAM; SSF51045; WW domain; 1.
DR   PROSITE; PS01159; WW_DOMAIN_1; 1.
DR   PROSITE; PS50020; WW_DOMAIN_2; 1.
DR   PROSITE; PS01357; ZF_ZZ_1; 1.
DR   PROSITE; PS50135; ZF_ZZ_2; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233200};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Synapse {ECO:0000256|ARBA:ARBA00023018};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00228}.
FT   DOMAIN          336..369
FT                   /note="WW"
FT                   /evidence="ECO:0000259|PROSITE:PS50020"
FT   DOMAIN          589..645
FT                   /note="ZZ-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50135"
FT   COILED          210..237
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          777..811
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          849..883
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   949 AA;  108880 MW;  785A6325A9D528D5 CRC64;
     IVFLVFALKS VLSDIRIDIQ AEIDAHNDIF KSIDGNRQKM VKALGNSEEA TMLQHRLDDM
     NQRWNDLKAK SASIRAHLEA SAEKWNRLLM SLEELIKWLN MKDEELKKQM PIGGDVPALQ
     LQYDHCKALR RELKEKEYSV LNAVDQARVF LADQPIEAPE EPRRNLQSKT ELSPEERAHK
     IAKAMRKQSS EVKEKWESLN AVTSNWQKQV DKALEKLRDL QGAMDDLDAD MKEAESVRNG
     WKPVGDLLID SLQDHIEKIM AFREEIAPIN LKVKTVNDLS SQLSPLDLHP SLKMSRQLDD
     LNMRWKLLQV SVDDRLKQLQ EAHRDFGPSS QHFLSTSVQL PWQRSISHNK VPYYINHQTQ
     TTCWDHPKMT ELFQSLADLN NIRFSAYRTA IKIRRLQKAL CLDLLELSTT NEIFKQHKLN
     QNDQLLSVPD VINCLTTTYD GLEQMHKDLV NVPLCVDMCL NWLLNVYDTG RTGKIRVQSL
     KIGLMSLSKG LLEEKYRYLF KEVAGPTEMC DQRQLGLLLH DAIQIPRQLG EVAAFGGSNI
     EPSVRSCFQQ NNNKPEISVK EFIDWMRLEP QSMVWLPVLH RVAAAETAKH QAKCNICKEC
     PIVGFRYRSL KHFNYDVCQS CFFSGRTAKG HKLHYPMVEY CIPTTSGEDV RDFTKVLKNK
     FRSKKYFAKH PRLGYLPVQT VLEGDNLETP ITLISMWPEH YDLSQSPQLF HDDTHSRIEQ
     YATRLAQMER TNGSFLTDSS STTGSVEDEH ALIQQYCQTL GGESPVSQPQ SPAQILKSVE
     REERGELERI IADLEEEQRN LQVEYEQLKD QHLRRGLPVG SPPESIVSPH HTSEDSELIA
     EAKLLRQHKG RLEARMQILE DHNKQLESQL HRLRQLLEQP ESDTRINGVS PWASPQHSAL
     SYSLDLDASG AQFHQAAGED LLAPPHDTST DLTEVMEQIH STFPSCCRE
//